{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:40:48Z","timestamp":1757623248425,"version":"3.44.0"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>This study presents a rare case of acinar soft tissue sarcoma and provides a detailed analysis of its multi-parameter quantitative functional MRI (fMRI) characteristics. The patient, a 16-year-old male, was diagnosed with acinar soft tissue sarcoma after presenting with a progressively enlarging mass in the right thigh. To determine the extent and nature of the lesion, MRI examinations were performed using conventional plain scans, contrast-enhanced scans, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and intravoxel incoherent motion (IVIM) for quantitative analysis. Functional MRI imaging not only provides crucial diagnostic and differential diagnostic information for acinar soft tissue sarcoma, but also reveals through DCE-MRI and IVIM imaging indicators that ASPS exhibits high cellular density, increased vascular permeability, and abundant neovascularization. The local microcirculation characteristics offer vital insights into the tumor\u2019s biological behavior and prognosis. Furthermore, functional MRI aids in precise diagnosis while providing references for surgical planning, postoperative adjuvant therapy, long-term follow-up evaluation, and recurrence risk prediction.<\/jats:p>","DOI":"10.3389\/fonc.2025.1602577","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T04:19:58Z","timestamp":1757391598000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Functional MR imaging of alveolar soft part sarcoma"],"prefix":"10.3389","volume":"15","author":[{"given":"Jie","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoyang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiuming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihua","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1097\/PAS.0000000000001552","article-title":"The 2020 WHO Classification: what\u2019s new in soft tissue tumor pathology","volume":"45","author":"Kallen","year":"2021","journal-title":"AmJ Surg Pathol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1735501","article-title":"Imaging and pathological features of alveolar soft part sarcoma: analysis of 16 patients","volume":"31","author":"Gulati","year":"2021","journal-title":"Indian J Radiol Imaging."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.3390\/clinpract13060123","article-title":"Imaging features of alveolar soft part sarcoma: single institution experience and literature review","volume":"13","author":"Spinnato","year":"2023","journal-title":"Clin Pract"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.937112","article-title":"Alveolar soft part sarcoma in childhood and adolescence: Report of three cases and review of literature","volume":"10","author":"Zhang","year":"2022","journal-title":"Front Pediatr"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1186-x","article-title":"Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution","volume":"17","author":"Pennacchioli","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.21037\/qims-23-743","article-title":"The dynamic contrast enhanced-magnetic resonance imaging and diffusion-weighted imaging features of alveolar soft part sarcoma","volume":"13","author":"Kim","year":"2023","journal-title":"Quant Imaging Med Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s40644-020-00352-9","article-title":"iCREATE: imaging features of primary and metastatic alveolar soft part sarcoma from the EORTC CREATE study","volume":"20","author":"Mcaddy","year":"2020","journal-title":"Cancer Imaging."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/1097-0142(19890101)63:1<1:aid-cncr2820630102>3.0.co;2-e","article-title":"Alveolar soft-part sarcoma. 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