{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T18:08:30Z","timestamp":1757614110377,"version":"3.44.0"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T00:00:00Z","timestamp":1757030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Meigs syndrome is characterized by the association of a benign ovarian tumor, typically an ovarian fibroma, with pleural effusion and ascites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case summary<\/jats:title><jats:p>This report presents a case of a 54-year-old woman who was misdiagnosed with malignant ovarian neoplasm due to the presence of significant abdominal distension and elevated CA125 levels. Initial imaging at multiple external facilities suggested a left-sided malignant ovarian tumor, leading to unnecessary delays in treatment. Upon admission to our institution in April 2024, imaging confirmed a large pelvic mass, and subsequent diagnostic procedures indicated a likely fibroma. Surgical intervention revealed a left ovarian thecoma, and post-operative pathology confirmed the diagnosis. Notably, CA125 levels decreased from 335.1 U\/ml to 164.6U\/ml following surgery, and the patient showed significant clinical improvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case underscores the importance of considering Meigs syndrome in patients presenting with ovarian masses, pleural effusions, and elevated CA125, to prevent misdiagnosis and ensure timely management.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2025.1624376","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T04:12:20Z","timestamp":1757045540000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Meigs syndrome was misdiagnosed as a malignant ovarian tumor: a case report"],"prefix":"10.3389","volume":"15","author":[{"given":"Hongmei","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanli","family":"Xing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangyang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lizhi","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2107","DOI":"10.1056\/NEJMicm2313447","article-title":"Meigs\u2019 Syndrome","volume":"390","author":"Fernandez Diaz","year":"2024","journal-title":"N Engl J 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