{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T11:59:15Z","timestamp":1780919955504,"version":"3.54.1"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that presents with nonspecific clinical manifestations and imaging features. It is more prevalent in elderly patients, with cases in children being extremely rare. This article presents a case study of a 10-year-old male patient who exhibited symptoms of swelling and pain in the left cheek for a duration of two weeks. Cone beam computed tomography (CBCT) demonstrated a hypodense lesion involving the left maxilla, with extension into the maxillary sinus and buccal cortical expansion. The patient underwent decompression, and histopathological examination of the intraoperative specimen suggested a diagnosis of calcifying odontogenic cyst (COC). One year after decompression, the patient underwent a tumor resection and the diagnosis of DGCT was confirmed by the post-operative pathology. Six months after tumor resection, CBCT showed complete bone remodeling in the lesion area. The patient is currently undergoing regular follow-up. This case provides an important reference for the diagnosis and treatment of pediatric DGCT, helping clinicians to develop individualised treatment plans.<\/jats:p>","DOI":"10.3389\/fonc.2025.1665311","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:11:51Z","timestamp":1764047511000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pediatric dentinogenic ghost cell tumor: a case report and review of the literature"],"prefix":"10.3389","volume":"15","author":[{"given":"Linlin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingchao","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianli","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HongSheng","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4625-46.2.10","article-title":"Dentinogenic Ghost Cell Tumor associated with Odontoma: A unique Histopathological Entity and its Surgical Management","volume":"46","author":"Urs","year":"2022","journal-title":"J Sci J Clin Pediatr Dent"},{"key":"B2","doi-asserted-by":"publisher","first-page":"14","DOI":"10.4322\/acr.2024.510","article-title":"Unravelling the mystery of the central dentinogenic ghost cell tumor- a rare case report and recurrent insights","volume":"15","author":"Yadav","year":"2024","journal-title":"J Sci Autops Case Rep"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1972.tb01666.x","article-title":"The calcifying ghost cell odontogenic tumor - or the calcifying odontogenic cyst","volume":"1","author":"Fejerskov","year":"1972","journal-title":"J Sci J Oral Pathol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3109\/00016358109162284","article-title":"Calcifying odontogenic cyst. 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