{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T17:00:28Z","timestamp":1770224428452,"version":"3.49.0"},"reference-count":9,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ovarian mucinous cystadenocarcinoma is a rare malignant epithelial tumor, accounting for approximately 10\u201315% of ovarian carcinomas. It typically presents with nonspecific abdominal symptoms and may reach a large size before detection. Presentation as an acute abdomen is uncommon and usually reflects advanced disease complicated by rupture or extensive peritoneal carcinomatosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 70-year-old postmenopausal woman presented with severe abdominal pain, vomiting, and fever. Laboratory evaluation revealed marked leukocytosis and elevated inflammatory markers. Imaging demonstrated a large multiloculated left adnexal cystic mass measuring 20 \u00d7 12 cm, associated with massive ascites and omental thickening. Due to signs of acute abdomen and clinical deterioration, urgent exploratory laparotomy was performed. Intraoperatively, diffuse peritoneal carcinomatosis and a large left ovarian mass were identified, and approximately 12 liters of mucinous fluid were drained. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, infracolic omentectomy, and appendectomy. Histopathological examination confirmed mucinous adenocarcinoma. The postoperative course was uneventful, and the patient demonstrated good recovery at six-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ovarian mucinous adenocarcinoma may rarely present as an acute abdomen due to extensive peritoneal involvement. Early recognition, thorough exclusion of alternative acute abdominal etiologies, accurate histopathological diagnosis, and multidisciplinary management are essential for optimal outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2025.1722960","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T05:34:20Z","timestamp":1770183260000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Mucinous adenocarcinoma with peritoneal carcinomatosis presenting as acute abdomen: a case report"],"prefix":"10.3389","volume":"15","author":[{"given":"Resul","family":"Nusreto\u011flu","sequence":"first","affiliation":[{"name":"General Surgery Department, Mogadishu Somali\u2013T\u00fcrkiye Recep Tayyip Erdo\u011fan Training and Research Hospital","place":["Mogadishu, Somalia"]},{"name":"Benadir University","place":["Mogadishu, Somalia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullahi Khalif","family":"Ali","sequence":"additional","affiliation":[{"name":"General Surgery Department, Mogadishu Somali\u2013T\u00fcrkiye Recep Tayyip Erdo\u011fan Training and Research Hospital","place":["Mogadishu, Somalia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181cf3d79","article-title":"The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory","volume":"34","author":"Kurman","year":"2010","journal-title":"Am J Surg pathology"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200307000-00014","article-title":"Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine practice with a new approach to improve intraoperative diagnosis","volume":"27","author":"Seidman","year":"2003","journal-title":"Am J Surg pathology"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1017\/S146239940800077X","article-title":"Critical molecular abnormalities in high-grade serous carcinoma of the ovary","volume":"10","author":"K\u00f6bel","year":"2008","journal-title":"Expert Rev Mol Med"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3180690d2d","article-title":"Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification","volume":"32","author":"Yemelyanova","year":"2008","journal-title":"Am J Surg pathology"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-012-1203-5","article-title":"Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features","volume":"460","author":"Prat","year":"2012","journal-title":"Virchows Archiv"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200011000-00001","article-title":"Mucinous tumors of the ovary: A clinicopathologic study of 196 borderline tumors (of intestinal type) and carcinomas, including an evaluation of 11 cases withPseudomyxoma peritonei\u2019","volume":"24","author":"Lee","year":"2000","journal-title":"Am J Surg pathology"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.2174\/1573408054022199","article-title":"Proteolytic enzymes and their inhibition in epithelial ovarian cancer","volume":"1","author":"Smedts","year":"2005","journal-title":"Curr Enzyme Inhibition"},{"key":"B8","article-title":"Evaluation and management of adnexal masses","volume":"128","author":"Eskander","year":"2016","journal-title":"Obstetrics Gynecology"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(03)00061-3","article-title":"Pathology of ovarian carcinoma","volume":"17","author":"Seidman","year":"2003","journal-title":"Hematology\/clinics North America"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1722960\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T05:34:20Z","timestamp":1770183260000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1722960\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,4]]},"references-count":9,"alternative-id":["10.3389\/fonc.2025.1722960"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2025.1722960","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,4]]},"article-number":"1722960"}}