{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:54:47Z","timestamp":1789556087176,"version":"build-2803163510"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Endobronchial aspergilloma (EBA) represents an uncommon manifestation of pulmonary aspergillosis that may co-occur with other significant respiratory pathologies, notably lung cancer and pulmonary embolism (PE), complicating diagnosis and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>An 83-year-old male with a history of benign prostatic hyperplasia surgery presented with chest pain. Computed tomography angiography (CTA) of the pulmonary arteries revealed both PE and a left hilar mass. Fiberoptic bronchoscopy disclosed a yellow, mushroom-like lesion, with histological examination confirming squamous cell carcinoma. Subsequent bronchoalveolar lavage culture was positive for Aspergillus flavus, confirming the diagnosis of EBA. Despite initiated treatments, the patient declined further therapeutic interventions and succumbed one month following presentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case underscores the rare coexistence of EBA, lung cancer, and PE, highlighting considerable diagnostic challenges and the need for integrated multidisciplinary management strategies in such complex presentations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2025.1724471","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T05:16:33Z","timestamp":1764825393000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Coexistence of endobronchial aspergilloma, pulmonary embolism, and lung cancer: a case report"],"prefix":"10.3389","volume":"15","author":[{"given":"Chen","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanshi","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.4540","article-title":"Endobronchial aspergilloma: A case report and literature review","volume":"14","author":"Huang","year":"2017","journal-title":"Exp Ther Med"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2011.06.005","article-title":"Two cases of endobronchial carcinoid masked by superimposed aspergillosis: A review of the literature of primary lung cancers associated with Aspergillus","volume":"17","author":"Nilsson","year":"2013","journal-title":"Ann Diagn Pathol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003743","article-title":"Aspergillus fumigatus\u2014what makes the species a ubiquitous human fungal pathogen","volume":"9","author":"Kwon-Chung","year":"2013","journal-title":"PLoS Pathog"},{"key":"B4","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1128\/CMR.00014-07","article-title":"Fusarium infections in immunocompromised patients","volume":"20","author":"Nucci","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2014-206291","article-title":"The clinical spectrum of pulmonary aspergillosis","volume":"70","author":"Kosmidis","year":"2015","journal-title":"Thorax"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112147-20220314-00203","article-title":"Research progress on non-surgical local treatment of pulmonary aspergilloma","volume":"6","author":"Ji","year":"2022","journal-title":"Chin J Tuberc Respir Dis"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2000.41.3.422","article-title":"A case of endobronchial aspergilloma","volume":"41","author":"Kim","year":"2000","journal-title":"Yonsei Med J"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2011.52.5.787","article-title":"Endobronchial aspergilloma: Report of 10 cases and literature review","volume":"52","author":"Ma","year":"2011","journal-title":"Yonsei Med J"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.4103\/ijpm.ijpm_116_21","article-title":"Endobronchial aspergilloma: benign appearance with potentially fatal consequences","volume":"65","author":"Itzakian","year":"2022","journal-title":"Indian J Pathol Microbiol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1136\/thx.7.4.317","article-title":"Broncho-pulmonary aspergillosis; 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