{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T14:35:03Z","timestamp":1776868503985,"version":"3.51.2"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Colorectal cancer (CRC) is a major public health concern that affects patients\u2019 quality of life (QoL) and imposes challenges on families and healthcare systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess QoL and its determinants among CRC patients in Qatar and identify sociodemographic and clinical factors influencing QoL in 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An analytical cross-sectional study was conducted between July and December 2023. From the National Center for Cancer Care and Research (NCCCR) registry, 456 CRC patients were screened, and 169 eligible participants were included. QoL was evaluated using the EORTC QLQ-C30 and the CRC-specific QLQ-CR29 tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most patients were aged \u226545 years (80.5%), non-Qatari (79.9%), and married (88.8%). Hypertension (39.1%) and diabetes (31.4%) were the most common comorbidities. Adenocarcinoma was predominant (90.5%), with most cases diagnosed at advanced stages (III\u2013IV, 74.8%) and metastasis in 71.6%. The sigmoid colon was the most common site (34.9%), and combined surgery and chemotherapy were the main treatments (69.2%). Global QoL was moderate to high (70.4 \u00b1 18.5), with fatigue (23.9 \u00b1 26.8) and financial difficulties (28.9 \u00b1 40.4) as the most reported concerns. Functional QoL was higher among those with sufficient income (+12.5 points, p &amp;lt; 0.01) and longer time since diagnosis (+0.06 points\/month, p &amp;lt; 0.05), but lower among those with higher education (\u20135.0 points, p = 0.05) or alcohol use (\u201311.2 points, p = 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite advanced disease stages, CRC patients in Qatar reported good QoL. Socioeconomic status significantly influenced outcomes, highlighting the need for integrated psychosocial and financial support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2025.1730212","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T10:28:52Z","timestamp":1770805732000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality of life outcomes in colorectal cancer survivors: insights from an analytical study at a tertiary cancer center-Qatar"],"prefix":"10.3389","volume":"15","author":[{"given":"Nada","family":"Adli","sequence":"first","affiliation":[{"name":"Community and Preventive Medicine Specialist, Preventive Medicine Division, Department of Internal Medicine, Hamad Medical Corporation (HMC)","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Adil Arbab","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Qatar Cancer Society","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nahlah","family":"AlMesbah","sequence":"additional","affiliation":[{"name":"Community and Preventive Medicine Specialist, Preventive Medicine Division, Department of Internal Medicine, Hamad Medical Corporation (HMC)","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagah","family":"Selim","sequence":"additional","affiliation":[{"name":"Community and Preventive Medicine Department, Primary Health Care Corporation (PHCC)","place":["Doha, Qatar"]},{"name":"Professor of Public Health and Preventive Medicine, Cairo University","place":["Ciro, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Abdelsalam Elimam","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Community and Preventive Medicine Department, Hamad Medical Corporation (HMC)","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujood Abdulwakeel Musa","family":"Awadelseed","sequence":"additional","affiliation":[{"name":"Community and Preventive Medicine Department, Hamad Medical Corporation (HMC)","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Iheb","family":"Bougmiza","sequence":"additional","affiliation":[{"name":"Community and Preventive Medicine Department, Primary Health Care Corporation (PHCC)","place":["Doha, Qatar"]},{"name":"College of Medicine, Qatar University","place":["Doha, Qatar"]},{"name":"Professor of Community Medicine, Sousse University","place":["Sousse, Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi Mohamad Abu","family":"Rasheed","sequence":"additional","affiliation":[{"name":"Qatar Cancer Society","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kakil","family":"Rasul","sequence":"additional","affiliation":[{"name":"Oncology Department, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC)","place":["Doha, Qatar"]},{"name":"Associate Professor in Clinical Medicine at Weill Cornell Medicine","place":["Doha, Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"B1","unstructured":"Latest global cancer data: Cancer burden rises to 19.3 million new cases and 10.0 million cancer deaths in 2020\n          \n          Lyon, France\n          IARC\n          \n          2020"},{"key":"B2","unstructured":"GLOBOCAN 2020: new global cancer data\n          \n          \n          UICC"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1136\/GUTJNL-2015-310912\/-\/DC1","article-title":"Global patterns and trends in colorectal cancer incidence and mortality","volume":"66","author":"Arnold","year":"2017","journal-title":"Gut"},{"key":"B4","first-page":"965","article-title":"Screening for colorectal cancer","volume":"164","author":"Wright","year":"2001","journal-title":"CMAJ: Can Med Assoc J"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.06.010","article-title":"Quality of life among long-term (\u22655 years) colorectal cancer survivors - systematic review","volume":"46","author":"Jansen","year":"2010","journal-title":"Eur J Cancer"},{"key":"B6","unstructured":"EORTC QLQ-C30 reference values manual. 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