{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:37:49Z","timestamp":1773920269757,"version":"3.50.1"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the clinical manifestations and ultrasonographic features of struma ovarii.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The clinical data, ultrasound characteristics and serological tumor markers of 20 cases of struma ovarii, confirmed by postoperative pathological examination at our hospital, were retrospectively analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 20 patients with benign struma ovarii were enrolled for the present study. None of the patients presented with ascites, and tumor markers were within normal ranges in all cases. Among the included patients,18 were over 30 years of age, 18 had cystic or cystic-solid masses, 19 had regular morphology, and 18 had well-defined borders without adhesion to surrounding tissues. Of note, 11 patients had irregular band-like septation within the masses, nine showed mural nodules, and six had \u201cthyroid pearls\u201d inside the masses. All patients underwent laparoscopic surgery, and no postoperative recurrences were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical manifestations of struma ovarii are nonspecific, and its ultrasonographic features are heterogeneous. Most masses are cystic or cystic-solid, with regular morphology, well-defined borders, and no adhesion to surrounding tissues, with some containing internal septa or solid mural nodules. Among the observed features, the presence of \u201cthyroid pearls\u201d represents a relatively specific finding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1721601","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T06:50:25Z","timestamp":1773903025000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of ultrasound features and clinical manifestations of struma ovarii"],"prefix":"10.3389","volume":"16","author":[{"given":"Liang","family":"Hou","sequence":"first","affiliation":[{"name":"Department of Ultrasound, The Second Qilu Hospital of Shandong University","place":["Jinan, Shandong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yixin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, The Second Qilu Hospital of Shandong University","place":["Jinan, Shandong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feixue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The Second Qilu Hospital of Shandong University","place":["Jinan, Shandong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lulu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Second Qilu Hospital of Shandong University","place":["Jinan, Shandong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuliang","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The Second Qilu Hospital of Shandong University","place":["Jinan, Shandong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The Second Qilu Hospital of Shandong University","place":["Jinan, Shandong, 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