{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T05:07:55Z","timestamp":1776834475485,"version":"3.51.2"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>This report describes a rare testicular mucinous cystic neoplasm in a 78-year-old man who underwent scrotal exploration and right radical orchiectomy. Histopathology of the resected specimen was interpreted as an ovarian-type mucinous cystadenoma with focal epithelial proliferation. Six months after surgery, follow-up imaging demonstrated multiple abdominal and peritoneal lesions suspicious for disseminated disease. Because the abdominal lesions were diagnosed radiologically and were not histologically sampled, metastatic disease could not be pathologically confirmed. In addition, immunohistochemical analysis of the orchiectomy specimen was not performed, and a gastrointestinal primary tumor was not definitively excluded by endoscopic evaluation. The case highlights the diagnostic challenges of distinguishing benign, borderline, malignant, and metastatic mucinous tumors involving the testis, and it emphasizes the importance of postoperative surveillance, comprehensive clinicopathologic correlation, immunohistochemistry, and exclusion of an extratesticular primary site.<\/jats:p>","DOI":"10.3389\/fonc.2026.1731890","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T04:33:30Z","timestamp":1776832410000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Abdominal disseminated lesions following surgery for a testicular mucinous cystic neoplasm initially diagnosed as mucinous cystadenoma: a case report and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Junjie","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Urology, Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weida","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology, Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianchang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2022.06.016","article-title":"The 2022 World Health Organization classification of tumours of the urinary system and male genital organs-part a: renal, penile, and testicular tumours","volume":"82","author":"Moch","year":"2022","journal-title":"Eur Urol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2002.01409.x","article-title":"Mucinous cystadenoma of the testis","volume":"52","author":"Nokubi","year":"2002","journal-title":"Pathol Int"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1206697","article-title":"Case report: Misdiagnosis of primary mucinous cystadenoma of the testicle by ultrasound","volume":"13","author":"Zhang","year":"2023","journal-title":"Front Oncol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200309000-00005","article-title":"Primary mucinous tumors of the testis and paratestis: a report of nine cases","volume":"27","author":"Ulbright","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2010.11.021","article-title":"Mucinous cystadenocarcinoma of the testis: a case report","volume":"42","author":"Iuga","year":"2011","journal-title":"Hum Pathol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/685946","article-title":"Primary mucinous adenocarcinoma of the testis","volume":"2012","author":"Azuma","year":"2012","journal-title":"Case Rep Med"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-023-01832-7","article-title":"Primary testicular mucinous adenocarcinoma-a case report and review of literature","volume":"15","author":"Ramakrishnan","year":"2024","journal-title":"Indian J Surg Oncol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14163882","article-title":"Testicular germ cell tumours-the role of conventional ultrasound","volume":"14","author":"Belfield","year":"2022","journal-title":"Cancers (Basel)"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14133180","article-title":"Imaging of pediatric testicular and para-testicular tumors: a pictural review","volume":"14","author":"Hermann","year":"2022","journal-title":"Cancers (Basel)"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.619774","article-title":"Primary borderline mucinous testicular tumor: a case report and literature review","volume":"10","author":"Hao","year":"2021","journal-title":"Front Oncol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2004.01631.x","article-title":"Immunohistochemical examination of mucinous cystadenoma of the testis","volume":"54","author":"Naito","year":"2004","journal-title":"Pathol Int"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1159\/000074432","article-title":"Tumor markers (CEA, CA 125, CYFRA 21-1, SCC and NSE) in patients with non-small cell lung cancer as an aid in histological diagnosis and prognosis. 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