{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T21:42:49Z","timestamp":1773265369906,"version":"3.50.1"},"reference-count":12,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pericardial effusion can occur as a complication of breast cancer and coronavirus disease (COVID-19). However, the specific characteristics of pericardial fluid in patients concurrently experiencing both conditions remain poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>This report describes a 52-year-old woman with a history of hypothyroidism, diabetes mellitus, and breast cancer who developed recurrent pericardial effusion complicated by cardiac tamponade following COVID-19 infection. The patient initially underwent pericardiocentesis and subsequently required pericardiectomy. Notably, the pericardial fluid obtained during pericardiocentesis exhibited a distinctive gelatinous appearance, a feature not previously described in association with breast cancer or COVID-19.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights the potential for unique interactions between breast cancer and COVID-19, particularly in the development of pericardial effusions with unusual characteristics and a gelatinous appearance. Further studies are warranted to elucidate the underlying mechanisms and clinical implications of this association.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1743453","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T05:37:13Z","timestamp":1773207433000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: A rare case of gelatinous pericardial effusion in a COVID-19 positive breast cancer patient"],"prefix":"10.3389","volume":"16","author":[{"given":"Nouf","family":"Alanazi","sequence":"first","affiliation":[{"name":"Cardiac Sciences Department, College of Medicine, King Saud University","place":["Riyadh, Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Abou Al-Saud","sequence":"additional","affiliation":[{"name":"Cardiac Sciences Department, College of Medicine, King Saud University","place":["Riyadh, Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Aljohani","sequence":"additional","affiliation":[{"name":"Cardiac Sciences Department, College of Medicine, King Saud University","place":["Riyadh, Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"AlSaleh","sequence":"additional","affiliation":[{"name":"Hematology and Oncology Department, College of Medicine, King Saud University","place":["Riyadh, Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd10090368","article-title":"Prevalence, risk factors, prognosis, and management of pericardial effusion in COVID-19","volume":"10","author":"Sara\u00e7","year":"2023","journal-title":"J Cardiovasc Dev 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