{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T06:20:14Z","timestamp":1773037214550,"version":"3.50.1"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>We report two cases of lung cancer that were surgically resected from patients with underlying bronchiectasis. These cases are unique because the tumors were diagnosed neither through elevated tumor markers, hypermetabolism on PET-CT, nor the presence of typical malignant imaging features. Instead, they were incidentally identified through histopathological examination following lobectomy performed for recurrent bronchiectasis-related infections. We aim to enhance clinicians\u2019 vigilance toward occult malignancies in patients with bronchiectasis by summarizing the treatment course of such concealed tumors. Bronchiectasis maybe associated with lung cancer. Implementing a regular imaging surveillance maybe necessary for these patients. Furthermore, timely surgical intervention should be considered when clinical or radiological findings raise suspicion of malignancy.<\/jats:p>","DOI":"10.3389\/fonc.2026.1751661","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T05:29:44Z","timestamp":1773034184000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Lung cancer masquerading in the background of bronchiectasis: a report of two cases and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Jian","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai Fourth People\u2019s Hospital, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqian","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai Fourth People\u2019s Hospital, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Shanghai Fourth People\u2019s Hospital, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuewei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shanghai Fourth People\u2019s Hospital, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohui","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai Fourth People\u2019s Hospital, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai Fourth People\u2019s Hospital, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/S2213-2600(21)00277-0","article-title":"Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations","volume":"10","author":"Aliberti","year":"2022","journal-title":"Lancet Respir Med"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2202819","article-title":"Bronchiectasis - A clinical review","volume":"387","author":"O\u2019Donnell","year":"2022","journal-title":"New Engl J Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/s41416-022-01775-w","article-title":"Cancer-inducing niche: the force of chronic inflammation","volume":"127","author":"Afify","year":"2022","journal-title":"Br J cancer"},{"key":"B4","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/s41392-021-00658-5","article-title":"Inflammation and tumor progression: signaling pathways and targeted intervention","volume":"6","author":"Zhao","year":"2021","journal-title":"Signal transduction targeted Ther"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3390\/life13020459","article-title":"Do patients with bronchiectasis have an increased risk of developing lung cancer? 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