{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:59:44Z","timestamp":1781153984256,"version":"3.54.1"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Breast cancer is a highly prevalent malignant tumor among women, showing a trend of younger onset. The disease - related stress can easily trigger an existential crisis and reduce the sense of meaning in life. However, the sense of meaning in life and psychological resilience are key psychological resources crucial for disease adaptation. Nevertheless, previous studies have mostly adopted cross - sectional designs, which limits the ability to clarify the dynamic evolution of these constructs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To explore the changes of latent categories of resilience over time in breast cancer patients and their correlation with the sense of meaning in life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A convenience sampling method was used to recruit 223 breast cancer patients. Measurements using the Connor-Davidson Resilience Scale and the Chinese version of the Meaning in Life Questionnaire were conducted at post-surgery (T1) and 3 months post-surgery (T2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At T1 and T2, there were two latent profile categories of psychological resilience, namely the low psychological resilience group (C1) and the high psychological resilience group (C2). The results of Latent Transition Analysis showed that 31.48% of breast cancer patients continued to be in the C2 group (persistent low - risk group), 25.25% of breast cancer patients continued to be in the C1 group (persistent high - risk group), 38.63% of breast cancer patients changed from the C1 group to the C2 group (Resilience Enhancing Group), and 5.64% of breast cancer patients changed from the C2 group to the C1 group (resilience decline group). Multivariate Logistic regression analysis showed that compared with the persistent low - risk group, breast cancer patients in the persistent high - risk group (OR\u00a0=\u00a09.488), the Resilience Enhancing Group (OR\u00a0=\u00a01.667), and the resilience decline group (OR\u00a0=\u00a04.899) had an increased risk of low life meaning (all P &amp;lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The latent change in resilience is significantly related to the meaning in life of breast cancer patients. Early identification and continuous psychological intervention are required to enhance the meaning in life of breast cancer patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1769713","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:35:25Z","timestamp":1781152525000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Latent transition analysis of resilience in breast cancer patients and its association with sense of meaning in life: a longitudinal follow - up study"],"prefix":"10.3389","volume":"16","author":[{"given":"Huiping","family":"Tian","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Affiliated Hospital of Hebei University","place":["BaoDing, Hebei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Affiliated Hospital of Hebei University","place":["BaoDing, Hebei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Affiliated Hospital of Hebei University","place":["BaoDing, Hebei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.6198","article-title":"Genetic and lifestyle factors for breast cancer risk assessment in Southeast China","volume":"12","author":"Zou","year":"2023","journal-title":"Cancer Med"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1111\/ajco.13958","article-title":"Incidence, mortality, survival, and disease burden of breast cancer in China compared to other developed countries","volume":"19","author":"Tao","year":"2023","journal-title":"Asia Pac J Clin Oncol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"103762","DOI":"10.1016\/j.breast.2024.103762","article-title":"The features of male breast cancer in China: A real-world study","volume":"76","author":"Gao","year":"2024","journal-title":"Breast"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1002\/cai2.93","article-title":"The road toward breast cancer single-disease quality control in China","volume":"2","author":"Lan","year":"2023","journal-title":"Cancer Innov"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000003278","article-title":"Incidence, mortality, and disability-adjusted life years of female breast cancer in China, 2022","volume":"137","author":"Sun","year":"2024","journal-title":"Chin Med J (Engl)"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.46234\/ccdcw2023.063","article-title":"Breast Cancer Awareness and Association with Frequency of Screening Among Women - China, 2020","volume":"5","author":"Bao","year":"2023","journal-title":"China CDC Wkly"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e54151","DOI":"10.1136\/bmjopen-2021-054151","article-title":"Occupational risk factors and breast cancer in Beijing, China: a hospital-based case-control study","volume":"12","author":"Li","year":"2022","journal-title":"BMJ Open"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19095547","article-title":"Meaning in Life and the Acceptance of Cancer: A Systematic Review","volume":"19","author":"Quinto","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"B9","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s00520-024-09115-9","article-title":"Effectiveness of meaning-centered interventions on anxiety and depressive symptoms, sense of meaning, and quality of life in patients with advanced cancer: a meta-analysis of randomized controlled trials","volume":"33","author":"Shen","year":"2025","journal-title":"Support Care Cancer"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4578","article-title":"Why is Meaning-Centered Group Psychotherapy (MCGP) effective? 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