{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T07:49:43Z","timestamp":1773733783019,"version":"3.50.1"},"reference-count":9,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Neuroblastoma in neonates is a rare solid tumor. This report presents two rare cases of cervical neuroblastoma, both characterized by stridor and coughing during feeding due to tumor compression. The first case of neuroblastoma presented with an intact capsule, allowing for complete surgical resection with preservation of the cervical vasculature and nerves. In contrast, although preoperative MRI indicated an intact capsule in the second case, the intraoperative findings revealed no discernible capsule formation and involvement of both the internal and external carotid arteries. None of the two patients developed Horner\u2019s syndrome postoperatively, and no evidence of recurrence or metastasis has been observed during the 10-month follow-up period. These cases also underscore that surgical intervention remains the primary treatment option for cervical neuroblastoma, particularly in alleviating the respiratory and feeding difficulties caused by tumor compression.<\/jats:p>","DOI":"10.3389\/fonc.2026.1776760","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T05:25:31Z","timestamp":1773725131000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Neuroblastoma in neonates: a case report and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Li","family":"Zhao","sequence":"first","affiliation":[{"name":"West China Second University Hospital, Sichuan University","place":["Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo","family":"Yu","sequence":"additional","affiliation":[{"name":"West China Second University Hospital, Sichuan University","place":["Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Jing","sequence":"additional","affiliation":[{"name":"West China Second University Hospital, Sichuan University","place":["Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kou","family":"Wei","sequence":"additional","affiliation":[{"name":"West China Second University Hospital, Sichuan University","place":["Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.soc.2020.11.010","article-title":"Management of neuroblastoma in pediatric patients","volume":"30","author":"Croteau","year":"2021","journal-title":"Surg Oncol Clinics North America"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e26905","article-title":"A case report of Balamuthia mandrillaris encephalitis","volume":"10","author":"Li","year":"2024","journal-title":"Heliyon"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-017-2761-2","article-title":"Spontaneous regression of neuroblastoma","volume":"372","author":"Brodeur","year":"2018","journal-title":"Cell Tissue Res"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(03)01166-5","article-title":"Neuroblastoma: biology and molecular and chromosomal pathology","volume":"4","author":"Schwab","year":"2003","journal-title":"Lancet Oncol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-018-2796-z","article-title":"Origin and initiation mechanisms of neuroblastoma","volume":"372","author":"Tsubota","year":"2018","journal-title":"Cell\u00a0Tissue Res"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-023-01332-y","article-title":"Neuroblastoma arises in early fetal development and its evolutionary duration predicts outcome","volume":"55","author":"K\u00f6rber","year":"2023","journal-title":"Nat Genet"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-021-00806-1","article-title":"Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma","volume":"53","author":"Jansky","year":"2021","journal-title":"Nat Genet"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-022-00643-z","article-title":"Advancing therapy for neuroblastoma","volume":"19","author":"Qiu","year":"2022","journal-title":"Nat Rev Clin Oncol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1002\/jso.27482","article-title":"Posttreatment complications in pediatric cervical neuroblastoma: A retrospective case series at a tertiary cancer center","volume":"129","author":"Lopez","year":"2023","journal-title":"J Surg Oncol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2026.1776760\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T05:25:32Z","timestamp":1773725132000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2026.1776760\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":9,"alternative-id":["10.3389\/fonc.2026.1776760"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2026.1776760","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"article-number":"1776760"}}