{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T04:59:11Z","timestamp":1785473951365,"version":"3.56.0"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pelvic solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm with marked clinical and radiological heterogeneity, posing significant diagnostic challenges. Standardized management strategies remain lacking for special clinical scenarios, including paraneoplastic syndromes, synchronous primary malignancies, and pregnancy-associated incidental diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-center retrospective case series included 3 consecutive patients with histologically confirmed pelvic SFT who underwent surgical resection at Peking University Third Hospital between October 2018 and September 2025. Clinical, radiological, surgical, pathological, and long-term follow-up data were systematically collected, and a narrative literature review was conducted to refine clinical management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The three patients presented with distinct rare phenotypes: a 17.5\u00a0cm giant tumor complicated by Doege-Potter syndrome, synchronous low-grade bladder urothelial carcinoma, and an asymptomatic tumor incidentally detected during twin pregnancy. All achieved R0 radical resection via individualized open, robot-assisted, or laparoscopic approaches, with no Clavien-Dindo grade \u2265II perioperative complications. All tumors showed characteristic nuclear STAT6 positivity and CD34 expression, with uncommon MDM2\/CDK4 and SMA\/desmin co-expression. At median 36-month follow-up (3\u201384 months), no recurrence or metastasis was observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Complete R0 resection is the cornerstone of pelvic SFT treatment. Individualized surgery is safe even for complex cases. STAT6 positivity is the diagnostic gold standard. High-risk patients may benefit from adjuvant radiotherapy, and lifelong follow-up is mandatory for late recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1782133","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T04:24:17Z","timestamp":1785471857000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pelvic solitary fibrous tumors: clinical manifestations, surgical management and long-term outcomes"],"prefix":"10.3389","volume":"16","author":[{"given":"Xinji","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Urology, Peking University Third Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University Third Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University Third Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7666","article-title":"A diagnostic challenge; 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