{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:46:21Z","timestamp":1782794781144,"version":"3.54.5"},"reference-count":7,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Primary breast lymphoma (PBL) is an exceptionally rare entity, accounting for only 0.3\u20130.5% of all breast lymphomas. The majority of reported cases are diffuse large B- cell lymphoma. Clinical and imaging findings often mimic breast carcinoma, and diagnosis is usually confirmed incidentally by biopsy. Recurrent breast abscesses in non-lactating women or in men should raise suspicion of underlying malignancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report the case of a 55-year-old non-lactating woman who presented to the surgical clinic with a non-healing wound following the incision and drainage of a recurrent breast abscess. A second excisional biopsy revealed primary classical Hodgkin lymphoma of the right breast, mixed cellularity subtype. The patient was treated with the BV-AD regimen, resulting in an excellent clinical response and complete wound healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights the importance of considering malignant etiologies, including rare lymphomas, in patients with recurrent breast abscesses. It underscores the diagnostic challenges posed by overlapping features with breast carcinoma and contributes to the limited literature on primary classical Hodgkin lymphoma of the breast.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1798122","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:25:37Z","timestamp":1782793537000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary classical Hodgkin lymphoma of breast presenting as recurrent breast abscess in a non-lactating woman: a case report and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Aliaa","family":"Khalili","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Al-Quds University (AQU)","place":["East Jerusalem, Palestine"]},{"name":"Department of Hematology and Oncology, Dura Governmental Hospital","place":["Hebron, Palestine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahaa Ibrahim","family":"AbuRahmeh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Palestine Polytechnic University","place":["Hebron, Palestine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibtihal Ahmad","family":"SA","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Palestine Polytechnic University","place":["Hebron, Palestine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazim","family":"Abosondos","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Dura Governmental Hospital","place":["Hebron, Palestine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"Altell","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Al-Quds University (AQU)","place":["East Jerusalem, Palestine"]},{"name":"Department of Hematology and Oncology, Dura Governmental Hospital","place":["Hebron, Palestine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Ameen","family":"Ishqair","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Al-Quds University (AQU)","place":["East Jerusalem, Palestine"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920201)69:3<725::aid-cncr2820690320>3.0.co;2-c","article-title":"Primary non-hodgkin's lymphomas of the female breast","volume":"69","author":"Giardini","year":"1992","journal-title":"Cancer"},{"key":"B2","doi-asserted-by":"crossref","DOI":"10.1002\/1097-0142(197201)29:1<252::AID-CNCR2820290138>3.0.CO;2-#","article-title":"Occurrence and prognosis of extranodal lymphomas","volume":"29","author":"Freeman","year":"1972","journal-title":"Cancer"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.4172\/2329-6917.1000238","article-title":"Primary breast lymphoma with unconventional presentation: a case report","volume":"5","author":"Nisar","year":"2017","journal-title":"J Leukemia"},{"key":"B4","article-title":"Primary non-hodgkin\u2019s lymphoma of the breast: a case report","volume":"8","author":"Pandure","year":"2013","journal-title":"Internet J Med Update - Ejournal"},{"key":"B5","first-page":"e52342","article-title":"Non-hodgkin\u2019s lymphoma within a breast abscess in a male patient: a presentation and literature review of a rare case","volume":"16","author":"Kazi","year":"2024","journal-title":"Cureus"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2017.07.027","article-title":"What\u2019s new on primary hodgkin\u2019s lymphoma of the breast? a case report and review of the literature","volume":"38","author":"Faenza","year":"2017","journal-title":"Int J Surg Case Rep"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqy015.187","article-title":"205 the challenge of necrotic tissue for lymphoma work-up","volume":"149","author":"Alakeel","year":"2018","journal-title":"Am J Clin Pathol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2026.1798122\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:25:37Z","timestamp":1782793537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2026.1798122\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":7,"alternative-id":["10.3389\/fonc.2026.1798122"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2026.1798122","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,30]]},"article-number":"1798122"}}