{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T05:04:50Z","timestamp":1780031090153,"version":"3.53.1"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to describe the preliminary single-center clinical experience with membrane anatomy-based 3D laparoscopic partial nephrectomy (LPN) performed in a single stage for selected patients with ruptured renal angiomyolipoma (RAML), and to assess its perioperative feasibility and short-term outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single-center retrospective descriptive design was employed to collect clinical data from 12 patients with ruptured renal angiomyolipoma who were treated between January 2020 and December 2025. All patients underwent 3D LPN via a transabdominal approach, with strict adherence to membrane anatomy principles during surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 12 patients underwent 3D laparoscopic surgery for ruptured renal angiomyolipoma. All patients successfully completed the procedure without conversion to open surgery, and none required radical nephrectomy. The average surgical duration was 311.83 \u00b1 85.46 minutes, with a mean warm ischemia time of 25.5 \u00b1 11.02 minutes. Intraoperative blood loss averaged 327.00 \u00b1 114.00 mL, and 83.33% of patients required intraoperative blood transfusions. Pain levels progressively decreased after surgery, with average VAS scores of 4.00 \u00b1 1.00 at 24 hours and 3.20 \u00b1 0.84 at 48 hours. Renal function markers showed transient fluctuations. The preoperative mean serum creatinine was 78.44 \u00b1 23.97 \u03bcmol\/L, which increased to 90.68 \u00b1 28.07 \u03bcmol\/L postoperatively, and then decreased to 85.55 \u00b1 22.84 \u03bcmol\/L at the 3-month follow-up. No tumor recurrence was observed during the postoperative follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Membrane anatomy-based 3D LPN for selected ruptured RAML cases showed acceptable perioperative safety, renal function preservation, and postoperative recovery, but requires validation in larger prospective comparative studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1819091","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T04:47:32Z","timestamp":1780030052000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical efficacy of membrane anatomy-based 3D laparoscopic partial nephrectomy in a single stage for the treatment of ruptured renal angiomyolipoma"],"prefix":"10.3389","volume":"16","author":[{"given":"Jiansheng","family":"Xiao","sequence":"first","affiliation":[{"name":"Department of Urology, The Sixth Affiliated Hospital of Jinan University, Dongguan Eastern Central Hospital","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Handa","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Urology, The Sixth Affiliated Hospital of Jinan University, Dongguan Eastern Central Hospital","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Interventional Vascular Surgery, The Sixth Affiliated Hospital of Jinan University, Dongguan Eastern Central Hospital","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology, The Sixth Affiliated Hospital of Jinan University, Dongguan Eastern Central Hospital","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Urology, The Sixth Affiliated Hospital of Jinan University, Dongguan Eastern Central Hospital","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohao","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Urology, The Sixth Affiliated Hospital of Jinan University, Dongguan Eastern Central Hospital","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoqiang","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Urology, The Sixth 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