{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:12:29Z","timestamp":1778562749220,"version":"3.51.4"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Littoral cell angioma (LCA) is a primary vascular tumor originating from the cells lining the sinuses of the red pulp. This case presents a 1-year-old male with thrombocytopenia incidentally detected by ultrasound as an isolated LCA. The tumor was evaluated via ultrasound, computed tomography, and biochemical testing. The patient underwent interventional embolization, with pathological examination confirming LCA diagnosis. Postoperatively, the lesion showed a stable reduction in size, platelet counts normalized, and no complications or recurrence occurred. This case analyzes the clinical, imaging, and pathological features of this rare splenic tumor, aiming to explore the clinical significance of interventional embolization for LCA with thrombocytopenia.<\/jats:p>","DOI":"10.3389\/fonc.2026.1820397","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:29:49Z","timestamp":1778560189000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Interventional treatment for littoral cell angioma of spleen-induced thrombocytopenia: a case report and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Zihao","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology and Vascular Anomalies, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University","place":["Guangzhou, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunshan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology and Vascular Anomalies, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University","place":["Guangzhou, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenyin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology and Vascular Anomalies, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University","place":["Guangzhou, Guangdong, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2015.76.1.55","article-title":"Littoral cell angioma in the spleen","volume":"76","author":"Gao","year":"2015","journal-title":"Br J Hosp Med"},{"key":"B2","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1097\/00000478-199111000-00001","article-title":"Littoral cell angioma. 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