{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T05:09:53Z","timestamp":1789016993545,"version":"build-2803163510"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the potential categories and influencing factors of quality of life management capability in elderly frail patients with colorectal cancer using latent profile analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study used convenience sampling to recruit patients from three tertiary hospitals between October 2023 and May 2025. Data were collected using multiple-scale surveys. Latent profile analysis (LPA) was used to identify potential categories and analyze influencing factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>\n                      A total of 280 patients were included. Quality of life management capability was divided into three categories: the low quality of life, low emotional level group (20.35%); the medium quality of life, low social function group (39.28%); and the high quality of life, high role management group (40.35%). Multivariable logistic regression showed that educational level, tumor stage, enterostomy status, family income, sex, disease acceptance, emotional level, self-efficacy, and social support level were the main influencing factors (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There is significant heterogeneity in the quality of life management capability of patients. Personalized interventions should be implemented based on category characteristics to improve quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1826323","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:30:35Z","timestamp":1789014635000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality of life management capability in elderly frail patients with colorectal cancer: a latent profile analysis"],"prefix":"10.3389","volume":"16","author":[{"given":"Wenyu","family":"Chai","sequence":"first","affiliation":[{"name":"Gansu Maternal and Child Health Care Hospital (Gansu Provincial Central Hospital)","place":["Lanzhou, Gansu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[{"name":"Gansu Maternal and Child Health Care Hospital (Gansu Provincial Central Hospital)","place":["Lanzhou, Gansu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ti","family":"Wang","sequence":"additional","affiliation":[{"name":"Gansu University of Chinese Medicine","place":["Lanzhou, Gansu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Xiang","sequence":"additional","affiliation":[{"name":"Gansu University of Chinese Medicine","place":["Lanzhou, Gansu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamei","family":"Li","sequence":"additional","affiliation":[{"name":"Gansu Maternal and Child Health Care Hospital (Gansu Provincial Central Hospital)","place":["Lanzhou, Gansu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"B1","article-title":"Development and application of a perioperative exercise program for elderly frail patients with colorectal cancer","volume":"59","author":"Wang","year":"2024","journal-title":"Chin J Nurs"},{"key":"B2","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1186\/s12877-023-03974-3","article-title":"Comparison of two frailty screening tools in older patients with colorectal cancer","volume":"23","author":"Zhao","year":"2023","journal-title":"BMC Geriatr"},{"key":"B3","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s12877-022-03703-2","article-title":"The relationship between the modified frailty index score (mFI-5), malnutrition, body composition, systemic inflammation and short-term clinical outcomes in patients undergoing surgery for colorectal cancer","volume":"23","author":"McGovern","year":"2023","journal-title":"BMC Geriatr"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1399490142","DOI":"10.1177\/10732748211059106","article-title":"Clinical preventive services and self-management practices among adult cancer survivors in the United States over time","volume":"28","author":"Findley","year":"2021","journal-title":"Cancer Control"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3724\/sp.j.1042.2020.01056","article-title":"Application of latent profile analysis in the field of organizational behavior","volume":"28","author":"Yin","year":"2020","journal-title":"Adv psychol Sci"},{"key":"B6","doi-asserted-by":"crossref","DOI":"10.1016\/S0959-8049(01)00448-8","article-title":"Quality of life research within the EORTC-the EORTC QLQ-C30. 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