{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T05:15:03Z","timestamp":1783574103747,"version":"3.55.0"},"reference-count":9,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>We report a 39-year-old woman with clear cell adenocarcinoma of the urethra (CCAU). She was treated with surgery alone and has survived 8 years without recurrence. The patient had painless hematuria. Imaging showed a 5.1\u00a0cm urethral mass. The tumor invaded the bladder and vagina (clinical stage T3N2M0). Urine cytology confirmed the diagnosis, which is unusual for CCAU. She underwent laparoscopic radical cystectomy, lymph node dissection, and cutaneous ureterostomy. Pathology showed clear cell adenocarcinoma with CK7+\/PAX8+. The final pathological stage was T3N0M0. She did not receive adjuvant therapy. Follow-up through January 2025 (8 years) showed no tumor recurrence, which appears to be rare among reported cases.<\/jats:p>","DOI":"10.3389\/fonc.2026.1841441","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T04:19:16Z","timestamp":1783570756000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Eight-year disease-free survival in clear cell adenocarcinoma of the urethra with surgery alone: a case report and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Ji","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Urology, Qingdao Municipal Hospital, Qingdao University","place":["Qingdao, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Sun","sequence":"additional","affiliation":[{"name":"Anesthesia and Operation Department, Qingdao Municipal Hospital, Qingdao University","place":["Qingdao, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Urology, Qingdao Municipal Hospital, Qingdao University","place":["Qingdao, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sichuan","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Urology, Qingdao Municipal Hospital, Qingdao University","place":["Qingdao, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology, Qingdao Municipal Hospital, Qingdao University","place":["Qingdao, Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/790235","article-title":"Clear cell adenocarcinoma of the 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