{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:04:58Z","timestamp":1789621498728,"version":"build-2803163510"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007452","name":"Wu Jieping Medical Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007452","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Aggressive Angiomyxoma (AAM) is a rare mesenchymal tumor characterized by local invasiveness and a high recurrence rate, often arising in the pelvis and perineum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report a 49-year-old woman presenting with a long-standing pelvic mass. Imaging suggested bilateral ovarian endometriomas and a deep pelvic lesion suspicious for AAM. The patient underwent total hysterectomy, bilateral adnexectomy, and complete resection of a pararectal mass via a pure transabdominal laparotomy, without any perineal incision or manipulation. Histopathology and immunohistochemistry confirmed pararectal Aggressive Angiomyxoma coexisting with bilateral ovarian endometriotic cysts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This rare combination highlights the importance of MRI in preoperative diagnosis and the challenges of surgical management for deep pelvic AAM. Complete resection and long-term follow-up are essential to reduce recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1843939","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:48:09Z","timestamp":1789620489000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pararectal aggressive angiomyxoma with bilateral ovarian endometriomas cysts: a rare case report"],"prefix":"10.3389","volume":"16","author":[{"given":"Nuowei","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangshu","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiazhen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Second Affiliated Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198307000-00009","article-title":"Aggressive angiomyxoma of the female pelvis and perineum. 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