{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:46:16Z","timestamp":1782794776553,"version":"3.54.5"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Percutaneous computed tomography (CT)-guided biopsy, including coaxial core needle biopsy (CCNB), has become the primary and preferred method for obtaining tissue samples in diagnosing or characterizing thoracic lesions, often in the lung or mediastinum. Despite advances in imaging and various approaches in reducing bleeding in the biopsy tract, pneumothorax and perilesional or lesional hemorrhage remain at the forefront of potentially serious complications. The increased risk that comes with requirements for additional tissue samples, both in size and in number, in the management of lung cancer is also a concern. Subsequent interventions may be required if significant pneumothorax or high-grade hemorrhage occurs and while death is a possible outcome with these procedures, it is rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>This report of a series of five image-guided CCNB cases focused on lung and mediastinal mass lesions in which hemostasis and biopsy tract closure were obtained with the SinglePass Kronos electrocautery device. All biopsy procedures were successful, and no complications were reported through 30 days post-procedure. Imaging confirmed the absence of post-procedure pneumothorax and bleeding complications in all five cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The SinglePass electrocautery device is a potentially valuable tool in minimizing pneumothorax and hemorrhagic complications in percutaneous lung and mediastinal mass CCNB procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1874234","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:25:13Z","timestamp":1782793513000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["SinglePass electrocautery device for closure of lung and mediastinal biopsy: a case series of 5 patients"],"prefix":"10.3389","volume":"16","author":[{"given":"Tust","family":"Techasith","sequence":"first","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Jairam","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Park","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Mesipam","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Baker","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Cristiano","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Velling","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trushar","family":"Patel","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behroz","family":"Oftadeh","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Dang","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey","family":"Young","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Raust","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Roughley","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurtizi","family":"Chavez","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander S.","family":"Misono","sequence":"additional","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian, Newport Radiology","place":["Newport Beach, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"191","DOI":"10.2147\/CEOR.S295494","article-title":"Costs of biopsy and complications in patients with lung cancer","volume":"13","author":"Chiu","year":"2021","journal-title":"Clinicoecon Outcomes Res"},{"key":"B2","doi-asserted-by":"publisher","first-page":"7330","DOI":"10.3390\/jcm13237330","article-title":"CT-guided transthoracic core-needle biopsy of pulmonary nodules: Current practices, efficacy, and safety considerations","volume":"13","author":"Constantinescu","year":"2022","journal-title":"J Clin Med"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-019-06377-4","article-title":"Diagnostic outcome and safety of CT-guided core needle biopsy for mediastinal masses: A systematic review and meta-analysis","volume":"30","author":"Lee","year":"2020","journal-title":"Eur Radiol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.21037\/qims-24-342","article-title":"Conventional versus cone-beam computed tomography in lung biopsy: Diagnostic performance, risks, and the advantages of tract embolization with gelfoam particle suspension","volume":"14","author":"Zou","year":"2024","journal-title":"Quant Imaging Med Surg"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2025.04.055","article-title":"CT-guided lung biopsy with needle embolization using gelatin sponge slurry to prevent pneumothorax and pulmonary hemorrhage: A propensity score matching controlled study","volume":"32","author":"Zhao","year":"2025","journal-title":"Acad Radiol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2022.05.019","article-title":"Biopsy-tract haemocoagulase injection reduces major complications after CT-guided percutaneous transthoracic lung biopsy","volume":"77","author":"Zhou","year":"2022","journal-title":"Clin Radiol"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07372-w","article-title":"Incidence, risk factors, and prognostic indicators of symptomatic air embolism after percutaneous transthoracic lung biopsy: A systematic review and pooled analysis","volume":"31","author":"Lee","year":"2021","journal-title":"Eur Radiol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11195894","article-title":"Diagnostic accuracy and complication of computed tomography (CT)-guided percutaneous transthoracic lung biopsy in patients 80 years and older","volume":"11","author":"Shin","year":"2022","journal-title":"J Clin Med"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.232168","article-title":"CT-guided coaxial lung biopsy: Number of cores and association with complications","volume":"313","author":"Kim","year":"2024","journal-title":"Radiology"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.671884","article-title":"Ultrasound-guided percutaneous core needle biopsy of peripheral pulmonary nodules \u2264 2 cm: Diagnostic performance, safety and influence factors","volume":"11","author":"Huang","year":"2021","journal-title":"Front Oncol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1186\/s12890-024-03343-9","article-title":"Nonlinear association between lung needle path CT attenuation values and postprocedural immediate pneumothorax following computed tomography-guided lung biopsy: A retrospective cohort study","volume":"24","author":"Zhou","year":"2024","journal-title":"BMC Pulm Med"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1097\/JCMA.0000000000000705","article-title":"Risk factors for pneumothorax and pulmonary hemorrhage following computed tomography-guided transthoracic core-needle biopsy of subpleural lung lesions","volume":"85","author":"Chiu","year":"2022","journal-title":"J Chin Med Assoc"},{"key":"B13","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1186\/s12890-021-01625-0","article-title":"The role of clinical characteristics and pulmonary function testing in predicting risk of pneumothorax by CT-guided percutaneous core needle biopsy of the lung","volume":"21","author":"Li","year":"2021","journal-title":"BMC Pulm Med"},{"key":"B14","doi-asserted-by":"publisher","first-page":"7348","DOI":"10.1038\/s41598-024-58045-3","article-title":"Incidence and risk factors for pulmonary hemorrhage after percutaneous CT-guided pulmonary nodule biopsy: An observational study","volume":"14","author":"He","year":"2024","journal-title":"Sci Rep"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.21037\/qims-22-176","article-title":"Development and validation of a prediction model of pneumothorax after CT-guided coaxial core needle lung biopsy","volume":"12","author":"Zhao","year":"2022","journal-title":"Quant Imaging Med Surg"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v31.i40.111158","article-title":"SinglePass Kronos electrocautery device for closure after percutaneous medical liver biopsy: Five case reports","volume":"31","author":"Misono","year":"2025","journal-title":"World J Gastroenterol"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2025.101229","article-title":"SinglePass Kronos electrocautery device for closure after percutaneous medical kidney biopsy: A series of five case reports","author":"Misono","year":"2025","journal-title":"Kidney Med"},{"key":"B18","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1186\/s12880-025-01794-y","article-title":"Development and validation of a risk nomogram predicting pneumothorax requiring chest tube placement post-percutaneous CT-guided lung biopsy","volume":"25","author":"Bondarenko","year":"2025","journal-title":"BMC Med Imaging"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.21037\/qims-19-1024","article-title":"Risk factors associated with pulmonary hemorrhage and hemoptysis following percutaneous CT-guided transthoracic lung core needle biopsy: A retrospective study of 1,090 cases","volume":"10","author":"Zhu","year":"2020","journal-title":"Quant Imaging Med Surg"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2021.09.006","article-title":"Safety and efficacy of percutaneous image-guided mediastinal mass core-needle biopsy","volume":"5","author":"Navin","year":"2021","journal-title":"Mayo Clin Proc Innov Qual Outcomes"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000335644.57481.97","article-title":"Current technological advances of bipolar coagulation","volume":"64","author":"Vellimana","year":"2009","journal-title":"Neurosurgery"},{"key":"B22","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jvir.2024.08.029","article-title":"Effectiveness of track cauterization in reduction of adverse events for lung microwave ablation","volume":"36","author":"Kim","year":"2025","journal-title":"J Vasc Interv Radiol"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-7-42","article-title":"Dissection of lung parenchyma using electrocautery is a safe and acceptable method for anatomical sublobar resection","volume":"7","author":"Ohtsuka","year":"2012","journal-title":"J Cardiothorac Surg"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2022.04.010","article-title":"Complications after transthoracic needle biopsy of pulmonary nodules: A population-level retrospective cohort analysis","volume":"19","author":"Vachani","year":"2022","journal-title":"J Am Coll Radiol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2026.1874234\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:25:13Z","timestamp":1782793513000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2026.1874234\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":24,"alternative-id":["10.3389\/fonc.2026.1874234"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2026.1874234","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,30]]},"article-number":"1874234"}}