{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:13:44Z","timestamp":1786115624864,"version":"build-2736575974"},"reference-count":48,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell non-Hodgkin lymphoma primarily associated with textured breast implants. Its pathological hallmarks include CD30 positivity, ALK negativity, and clonal T-cell receptor gene rearrangement. Complete surgical excision is the primary treatment modality, and early diagnosis combined with standardized management is associated with a favorable prognosis. We report a case of BIA-ALCL in a 47-year-old female who presented with breast swelling 20 years after receiving textured breast implants. To the best of our knowledge, this is the first documented case of BIA-ALCL in mainland China. Preoperative aspiration was not suggestive of BIA-ALCL, and the diagnosis was ultimately confirmed through histopathological examination of the capsule tissue. Based on a comprehensive postoperative systemic evaluation, no adjuvant therapy was required.<\/jats:p>","DOI":"10.3389\/fonc.2026.1889467","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T04:24:53Z","timestamp":1785990293000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Breast implant-associated anaplastic large cell lymphoma: a case report and literature review"],"prefix":"10.3389","volume":"16","author":[{"given":"Shuangyi","family":"Qi","sequence":"first","affiliation":[{"name":"Department of Breast Surgery, First Affiliated Hospital of Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Taishun County People\u2019s Hospital","place":["Wenzhou, 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