{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:02:52Z","timestamp":1789448572420,"version":"build-2803163510"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Cystic echinococcosis (CE), caused by\n                      <jats:italic>Echinococcus granulosus<\/jats:italic>\n                      , is a zoonotic parasitic disease that primarily affects the liver and lungs, with breast involvement being extremely rare. We report a case of breast CE in a 50-year-old Tibetan woman from an endemic area.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 50-year-old Tibetan woman from a pastoral area presented with a palpable mass in the left breast.Ultrasonography revealed a mixed-echoic nodule exhibiting a \u201ccerebral gyrus sign\u201d in the glandular layer of the left breast. MRI revealed an oval mass in the upper quadrant of the left breast, showing homogeneous high signal intensity on fat-suppressed T2-weighted images and thin peripheral ring enhancement. The final pathology diagnosis after surgery was breast CE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case highlights the ultrasonographic \u201ccerebral gyrus sign\u201d as a potential imaging clue for breast CE and emphasizes that hydatid disease should be considered in patients from endemic regions presenting with complex breast masses, even with negative serology. Increased awareness of this rare entity may help reduce misdiagnosis and guide appropriate clinical management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fonc.2026.1931802","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T04:26:36Z","timestamp":1789446396000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Breast cystic echinococcosis with ultrasonographic \u201ccerebral gyrus sign\u201d: a case report"],"prefix":"10.3389","volume":"16","author":[{"given":"Na","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Ultrasound, People\u2019s Hospital of Ganzi Tibetan Autonomous Prefecture","place":["Kangding, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongping","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of General Surgery, People\u2019s Hospital of Ganzi Tibetan Autonomous Prefecture","place":["Kangding, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hualin","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, West China Hospital, Sichuan University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, People\u2019s Hospital of Ganzi Tibetan Autonomous Prefecture","place":["Kangding, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i13.1425","article-title":"Worldwide epidemiology of liver hydatidosis including the Mediterranean area","volume":"18","author":"Grosso","year":"2012","journal-title":"World J 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