{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:25:53Z","timestamp":1778754353850,"version":"3.51.4"},"reference-count":10,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Ophthalmol."],"abstract":"<jats:p>A 40-year-old Asian Indian woman, diagnosed as having idiopathic panuveitis (elsewhere) 3 years earlier and being treated with oral steroids (20\u00a0mg\/day) and methotrexate (25\u00a0mg\/week), presented to us with worsening vision in both eyes. Her best corrected visual acuity (BCVA) was perception of light in her right eye and counting fingers close to face in her left eye. A slit lamp examination showed an anterior chamber (AC) reaction (1+) in both eyes with posterior synechia, a total cataract in her right eye, and pseudophakia in her left eye. The left fundus showed vitritis, vitreous membranes, chorioretinitis, multifocal areas of retinitis, and retinal vascular sheathing. A systemic examination showed extensive multifocal areas of tinea corporis on the hands and torso. Owing to the leukocytosis (22,000\u00a0cells\/mm<jats:sup>3<\/jats:sup>), diagnostic vitrectomy was initially deferred and 100\u00a0mg of oral itraconazole was given twice a day for 3 months. The vitritis improved a little and her total white blood cell (WBC) count improved with treatment of the skin infection. Following a diagnostic vitrectomy later in her left eye, resolving areas of retinitis were seen. Complete resolution of eye inflammation was seen at the end of 6 weeks. At the 6-month follow-up, her BCVA was 6\/18 in left eye and she was off oral steroids and methotrexate, with no recurrence of inflammation. We speculate a probable association between the ocular inflammation and extensive tinea corporis based on the therapeutic response to itraconazole.<\/jats:p>","DOI":"10.3389\/fopht.2023.1174414","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T05:04:41Z","timestamp":1686287081000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["A rare case report of panuveitis with retinochoroidal involvement, retinitis, and retinal vasculitis due to extensive tinea corporis"],"prefix":"10.3389","volume":"3","author":[{"given":"Vinaya Kumar","family":"Konana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalpana","family":"Babu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,6,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.8.2.240","article-title":"The dermatophytes","volume":"8","author":"Summerbell","year":"1995","journal-title":"Clin Microbiol Rev"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2015.11.010","article-title":"Ocular manifestations of infectious skin diseases","volume":"34","author":"Sadowska-Przytocka","year":"2016","journal-title":"Clinics Dermatol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03564.x","article-title":"Update on the prevention, diagnosis and management of cytomegalovirus infection during pregnancy","volume":"17","author":"Lazzarotto","year":"2011","journal-title":"Clin Microbiol Infect"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71925-7","article-title":"Herpes simplex chorioretinitis in a healthy adult","volume":"96","author":"Grutzmacher","year":"1983","journal-title":"Am J Ophthalmol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.oret.2019.05.023","article-title":"Early-stage multifocal candida chorioretinitis in an immunocompromised woman","volume":"3","author":"Chen","year":"2019","journal-title":"Ophthalmol Retina"},{"key":"B6","doi-asserted-by":"publisher","first-page":"2324709619881561","DOI":"10.1177\/2324709619881561","article-title":"Coccidioidomycosis chorioretinitis","volume":"7","author":"Nordstrom","year":"2019","journal-title":"J Invest Med High Impact Case Rep"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1976.03910040347009","article-title":"Granulomatous necrotizing retinochoroiditis caused by sporotrichum schenkii: report of a case including immunofluorescence and electron microscopical studies","volume":"94","author":"Font","year":"1976","journal-title":"Arch Ophthalmol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(82)34839-3","article-title":"Metastatic fungal chorioretinitis developing during trichosporon sepsis","volume":"89","author":"Walsh","year":"1982","journal-title":"Ophthalmology"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12348-019-0173-z","article-title":"Tinea corporis infection manifestating as retinochoroiditis\u2013an unusual presentation","volume":"9","author":"Agarwal","year":"2019","journal-title":"J Ophthalmic Inflammation Infect"},{"key":"B10","article-title":"Occlusive vasculitis with multifocal choroiditis in fungal skin infection","volume":"10","author":"Kawali.","year":"2019","journal-title":"EC Opthalmol"}],"container-title":["Frontiers in Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fopht.2023.1174414\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T05:04:44Z","timestamp":1686287084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fopht.2023.1174414\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,9]]},"references-count":10,"alternative-id":["10.3389\/fopht.2023.1174414"],"URL":"https:\/\/doi.org\/10.3389\/fopht.2023.1174414","relation":{},"ISSN":["2674-0826"],"issn-type":[{"value":"2674-0826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,9]]},"article-number":"1174414"}}