{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T05:25:16Z","timestamp":1764739516187,"version":"3.46.0"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Ophthalmol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>To report the management of a long-standing, large hyphema following vitrectomy with silicone oil tamponade using multiple anterior chamber paracentesis (ACP) or washout (ACW).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 50-year-old woman presented with blurred vision attributed to polypoidal choroidal vasculopathy and vitreous hemorrhage. Vitrectomy with silicone oil tamponade and lens extraction were performed. A persistent large hyphema and elevated intraocular pressure were detected postoperatively. ACP and ACW were performed five and two times, respectively. The hyphema faded, and the elevated IOP decreased to the normal range within 2 months. The cornea was clear, and corneal blood staining was not observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Multiple ACPs and ACWs are necessary and effective for the treatment of long-standing large hyphema.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fopht.2025.1621845","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T05:20:15Z","timestamp":1764739215000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Multiple anterior chamber paracentesis or washout for a large hyphema following vitrectomy with silicone oil tamponade"],"prefix":"10.3389","volume":"5","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2021.07.041","article-title":"Traumatic hyphema","volume":"61","author":"Genadry","year":"2021","journal-title":"J Emerg Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e40","DOI":"10.1056\/NEJMicm2201912","article-title":"Spontaneous hyphema","volume":"387","author":"Shah","year":"2022","journal-title":"N Engl J Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.survophthal.2015.11.005","article-title":"Controversies in the pathophysiology and management of hyphema","volume":"61","author":"Bansal","year":"2016","journal-title":"Surv Ophthalmol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1159\/000452254","article-title":"Risk factors of hyphema following surgeries for primary rhegmatogenous retinal detachment","volume":"236","author":"Kung","year":"2016","journal-title":"Ophthalmologica"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S332485","article-title":"Incidence of and risk factors for postoperative hyphema after 23-gauge pars plana vitrectomy for proliferative diabetic retinopathy","volume":"14","author":"Nie","year":"2021","journal-title":"Int J Gen Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.11.005","article-title":"Microincision vitrectomy surgery and intravitreal bevacizumab as a surgical adjunct to treat diabetic traction retinal detachment","volume":"116","author":"Oshima","year":"2009","journal-title":"Ophthalmology"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10078-1372","article-title":"Large hyphema following femtosecond laser-assisted cataract surgery (FLACS) and trabectome resulting in endocapsular hematoma","volume":"16","author":"Chang","year":"2022","journal-title":"J Curr Glaucoma Pract"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.3390\/diagnostics12041005","article-title":"Surgical treatment in silicone oil-associated glaucoma","volume":"12","author":"Cornacel","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02565.x","article-title":"Safety profile of anterior chamber paracentesis performed at the slit lamp","volume":"39","author":"Trivedi","year":"2011","journal-title":"Clin Exp Ophthalmol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2016-309650","article-title":"Safety of anterior chamber paracentesis using a 30-gauge needle integrated with a specially designed disposable pipette","volume":"101","author":"Kitazawa","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0000000000000939","article-title":"Complications of serial anterior chamber paracentesis for increased intraocular pressure after intravitreal injections","volume":"16","author":"Shah","year":"2022","journal-title":"Retin cases Brief Rep"}],"container-title":["Frontiers in Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fopht.2025.1621845\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T05:20:20Z","timestamp":1764739220000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fopht.2025.1621845\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,3]]},"references-count":11,"alternative-id":["10.3389\/fopht.2025.1621845"],"URL":"https:\/\/doi.org\/10.3389\/fopht.2025.1621845","relation":{},"ISSN":["2674-0826"],"issn-type":[{"value":"2674-0826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,3]]},"article-number":"1621845"}}