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Pain Res."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Quantitative sensory testing is often used to investigate pain in the context of experimental and clinical research studies. However, many of the devices used for QST protocols are only available in resource rich environments, thereby inadvertently limiting the possible pool of participants. Development of remote protocols for appropriate QST measures has the potential to reduce barriers to participation in research.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants with insomnia and Crohn's disease were recruited as part of a clinical trial. We adapted a remote version of the cold pressor test for use during telehealth-based study assessments. Herein, we present data from the baseline assessments including an assessment of feasibility and acceptability of the task.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>100% of participants (<jats:italic>N<\/jats:italic>\u2009=\u200928) were able to complete the remote cold pressor test using a combination of materials from their homes and mailed by the study team. Temperature changes during the test were minimal and fairly evenly balanced between increases and decreases. Correlations between submersion time and both general and disease specific pain trended toward significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We demonstrated that a remote version of the cold pressor test is feasible and acceptable in a clinical population and provided a step-by-step protocol for administration to facilitate use in other studies.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpain.2024.1421709","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T05:10:19Z","timestamp":1724130619000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility and acceptability of remote administration of the cold pressor test"],"prefix":"10.3389","volume":"5","author":[{"given":"Jessica K.","family":"Salwen-Deremer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamie M.","family":"Horrigan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J.","family":"Westvold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer A.","family":"Haythornthwaite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,8,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00784-021-04171-5","article-title":"Quantitative sensory testing in patients with the muscle pain subtype of temporomandibular disorder: a systemic review and meta-analysis","volume":"25","author":"Meng","year":"2021","journal-title":"Clin Oral Investig"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1097\/j.pain.0000000000001590","article-title":"Quantitative sensory testing and predicting outcomes for musculoskeletal pain, disability, and negative affect: a systematic review and meta-analysis","volume":"160","author":"Georgopoulos","year":"2019","journal-title":"Pain"},{"key":"B3","first-page":"121","article-title":"Chapter 8\u2014clinical neurophysiology of pain","volume-title":"Handb Clin Neurol","author":"Lefaucheur","year":"2019"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e1049","DOI":"10.1097\/PR9.0000000000001049","article-title":"Test-retest reliability of a simple bedside-quantitative sensory testing battery for chronic neuropathic pain","volume":"8","author":"Sachau","year":"2023","journal-title":"Pain Rep"},{"key":"B5","doi-asserted-by":"publisher","first-page":"463724","DOI":"10.1016\/j.chroma.2022.463724","article-title":"Dried blood microsampling-assisted therapeutic drug monitoring of immunosuppressants: an overview","volume":"1689","author":"Deprez","year":"2023","journal-title":"J Chromatogr A"},{"key":"B6","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.jim.2010.09.014","article-title":"Serum, plasma, and dried blood spot high-sensitivity C-reactive protein enzyme immunoassay for population research","volume":"362","author":"Brindle","year":"2010","journal-title":"J Immunol Methods"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1001\/jamaoto.2013.5338","article-title":"Diagnosis of obstructive sleep apnea by peripheral arterial tonometry: meta-analysis","volume":"139","author":"Yalamanchali","year":"2013","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"B8","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1080\/00365521.2020.1854342","article-title":"Self-monitoring with home based fecal calprotectin is associated with increased medical treatment. 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