{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:23:26Z","timestamp":1787027006775,"version":"build-2736575974"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pain Res."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cervicogenic headache (CEH) is often refractory to monotherapies, and treatment strategies combining neuromodulation and myofascial interventions may offer additional benefits. This study evaluated the clinical effectiveness of ultrasound-guided C2 dorsal root ganglion (DRG) pulsed radiofrequency (PRF) combined with suboccipital myofascial plane block (SMPB) in subjects with CEH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective study analyzed 67 CEH subjects treated with PRF alone (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200928) or combined PRF\u2009+\u2009SMPB therapy (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200939). Pain intensity (VAS), headache frequency and duration, Short-Form McGill Pain Questionnaire (SF-MPQ), and Neck Disability Index (NDI) were assessed at baseline, 1 week, 1 month, 3 months, and 6 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The combined treatment produced significantly greater improvement in pain outcomes. At 3 months, VAS scores were 2.09\u2009\u00b1\u20091.38 in the PRF\u2009+\u2009SMPB group vs. 3.55\u2009\u00b1\u20091.11 in the PRF group (between-group difference \u0394\u2009=\u2009\u22121.46; 95% CI \u22122.06 to \u22120.86;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001). Superior improvements were also observed in headache frequency, headache duration, SF-MPQ, and NDI at multiple timepoints. All subjects completed follow-up (attrition rate 0%), and no complications or minor adverse events were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Ultrasound-guided C2 DRG PRF combined with SMPB demonstrated greater reductions in pain and disability than PRF alone in CEH. These findings provide preliminary, hypothesis-generating evidence supporting the feasibility and clinical utility of this multimodal approach. Prospective randomized trials with longer follow-up are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpain.2026.1725798","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T07:25:31Z","timestamp":1769412331000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Combined ultrasound-guided C2 DRG pulsed radiofrequency and suboccipital myofascial plane block for cervicogenic headache: a retrospective study"],"prefix":"10.3389","volume":"7","author":[{"given":"Dan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Yanbian University Hospital","place":["Yanji, Jilin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pain, Yanbian University Hospital","place":["Yanji, Jilin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pain, Yanbian University Hospital","place":["Yanji, Jilin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meige","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pain, Yanbian University Hospital","place":["Yanji, Jilin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaichen","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pain, Yanbian University Hospital","place":["Yanji, Jilin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhe","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pain, Yanbian University Hospital","place":["Yanji, Jilin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1046\/j.1468-2982.1983.0304249.x","article-title":"\u201cCervicogenic\u201d headache. 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