{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:28:54Z","timestamp":1790389734242,"version":"4.1.0"},"reference-count":52,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"DOI":"10.3389\/fped.2017.00130","type":"journal-article","created":{"date-parts":[[2017,5,31]],"date-time":"2017-05-31T13:11:43Z","timestamp":1496236303000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":41,"title":["Dysmotility in Esophageal Atresia: Pathophysiology, Characterization, and Treatment"],"prefix":"10.3389","volume":"5","author":[{"given":"Christophe","family":"Faure","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Righini Grunder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,5,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1097\/MPG.0000000000001401","article-title":"ESPGHAN-NASPGHAN guidelines for the evaluation and treatment of gastrointestinal and nutritional complications in children with esophageal atresia-tracheoesophageal fistula","volume":"63","author":"Krishnan","year":"2016","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B2","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1097\/MPG.0b013e3182868773","article-title":"Characterization of esophageal motility following esophageal atresia repair using high-resolution esophageal manometry","volume":"56","author":"Lemoine","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1016\/j.jpedsurg.2007.08.023","article-title":"Lack of distal esophageal contractions is a key determinant of gastroesophageal reflux disease after repair of esophageal atresia","volume":"42","author":"Kawahara","year":"2007","journal-title":"J Pediatr Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1097\/SLA.0b013e3181c9b613","article-title":"Esophageal morbidity and function in adults with repaired esophageal atresia with tracheoesophageal fistula: a population-based long-term follow-up","volume":"251","author":"Sistonen","year":"2010","journal-title":"Ann Surg"},{"key":"B5","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1007\/BF00566486","article-title":"Esophageal atresia: long-term-follow-up of respiratory function, maximal working capacity, and esophageal function","volume":"10","author":"Montgomery","year":"1995","journal-title":"Pediatr Surg Int"},{"key":"B6","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1016\/S0022-3468(03)00110-6","article-title":"Long-term analysis of children with esophageal atresia and tracheoesophageal fistula","volume":"38","author":"Little","year":"2003","journal-title":"J Pediatr Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"2487","DOI":"10.1016\/j.jpedsurg.2013.07.019","article-title":"Esophageal atresia: gastroesophageal functional follow-up in 5-15 year old children","volume":"48","author":"Pedersen","year":"2013","journal-title":"J Pediatr Surg"},{"key":"B8","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/j.amjsurg.2014.09.019","article-title":"Esophageal atresia and transitional care \u2013 step 1: a systematic review and meta-analysis of the literature to define the prevalence of chronic long-term problems","volume":"209","author":"Connor","year":"2015","journal-title":"Am J Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1016\/j.jpedsurg.2015.07.002","article-title":"The evaluation of deglutition with videofluoroscopy after repair of esophageal atresia and\/or tracheoesophageal fistula","volume":"50","author":"Yalcin","year":"2015","journal-title":"J Pediatr Surg"},{"key":"B10","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1034\/j.1600-0455.2002.430511.x","article-title":"Videofluoroscopy of deglutition in children after repair of esophageal atresia","volume":"43","author":"H\u00f6rmann","year":"2002","journal-title":"Acta Radiol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1097\/00000658-197710000-00005","article-title":"Long-term esophageal function following repair of esophageal atresia","volume":"186","author":"Orringer","year":"1977","journal-title":"Ann Surg"},{"key":"B12","first-page":"116","article-title":"Motor function of the esophagus after repair of esophageal atresia and tracheoesophageal fistula","volume":"82","author":"Duranceau","year":"1977","journal-title":"Surgery"},{"key":"B13","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1007\/BF01297188","article-title":"Long-term evaluation of esophageal and pulmonary function in patients with repaired esophageal atresia and tracheoesophageal fistula","volume":"32","author":"Biller","year":"1987","journal-title":"Dig Dis Sci"},{"key":"B14","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1055\/s-2001-19718","article-title":"Manometric evaluation of postoperative patients of esophageal atresia and tracheo-esophageal fistula","volume":"11","author":"Dutta","year":"2001","journal-title":"Eur J Pediatr Surg"},{"key":"B15","doi-asserted-by":"publisher","first-page":"2496","DOI":"10.1016\/j.jpedsurg.2013.07.024","article-title":"Evaluation of gastroesophageal function and mechanisms underlying gastroesophageal reflux in infants and adults born with esophageal atresia","volume":"48","author":"van Wijk","year":"2013","journal-title":"J Pediatr Surg"},{"key":"B16","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1155\/2015\/787069","article-title":"Dysphagia among adult patients who underwent surgery for esophageal atresia at birth","volume":"29","author":"Huynh Trudeau","year":"2015","journal-title":"Can J Gastroenterol Hepatol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1016\/0022-3468(95)90029-2","article-title":"Ambulatory 24-hour manometric and pH metric evidence of permanent impairment of clearance capacity in patients with esophageal atresia","volume":"30","author":"Tovar","year":"1995","journal-title":"J Pediatr Surg"},{"key":"B18","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1055\/s-0035-1564715","article-title":"Evaluation of gastroesophageal reflux by combined multichannel intraluminal impedance and pH monitoring and esophageal motility patterns in children with esophageal atresia","volume":"26","author":"Tong","year":"2016","journal-title":"Eur J Pediatr Surg"},{"key":"B19","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1097\/MPG.0000000000000709","article-title":"Clinical relevance of esophageal baseline impedance measurement: just an innocent bystander","volume":"60","author":"Tambucci","year":"2015","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B20","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.jpedsurg.2011.04.093","article-title":"Evaluation of esophageal motility and reflux in children treated for esophageal atresia with the use of combined multichannel intraluminal impedance and pH monitoring","volume":"46","author":"Di Pace","year":"2011","journal-title":"J Pediatr Surg"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1016\/S0022-3468(98)90154-3","article-title":"Swallowing disorders after esophageal atresia evaluated with videomanometry","volume":"33","author":"Montgomery","year":"1998","journal-title":"J Pediatr Surg"},{"key":"B22","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1007\/s003830000348","article-title":"Cineradiographic evaluation of postoperative patients with esophageal atresia and tracheoesophageal fistula","volume":"16","author":"Dutta","year":"2000","journal-title":"Pediatr Surg Int"},{"key":"B23","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1055\/s-0031-1291269","article-title":"Incidence, diagnosis, and outcomes of vocal fold immobility after esophageal atresia (EA) and\/or tracheoesophageal fistula (TEF) repair","volume":"21","author":"Mortellaro","year":"2011","journal-title":"Eur J Pediatr Surg"},{"key":"B24","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1016\/j.jpeds.2010.12.006","article-title":"Symptomatic vocal cord paresis\/paralysis in infants operated on for esophageal atresia and\/or tracheo-esophageal fistula","volume":"158","author":"Morini","year":"2011","journal-title":"J Pediatr"},{"key":"B25","first-page":"130","article-title":"[Risk of recurrent laryngeal nerve palsy in surgery of esophageal atresia]","volume":"24","author":"Bargy","year":"1983","journal-title":"Chir Pediatr"},{"key":"B26","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1053\/jpsu.2000.6048","article-title":"Gastric motility disorders in patients operated on for esophageal atresia and tracheoesophageal fistula: long-term evaluation","volume":"35","author":"Romeo","year":"2000","journal-title":"J Pediatr Surg"},{"key":"B27","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/S0022-3468(87)80425-6","article-title":"Disorders of the esophageal motor activity in atresia of the esophagus","volume":"22","author":"Romeo","year":"1987","journal-title":"J Pediatr Surg"},{"key":"B28","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1097\/MPG.0b013e3181c1f596","article-title":"Esophageal motility in children with suspected gastroesophageal reflux disease","volume":"50","author":"Hoffman","year":"2010","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B29","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1007\/s003830050652","article-title":"Esophageal aperistalsis following fundoplication in a patient with trisomy 21","volume":"15","author":"Bozinovski","year":"1999","journal-title":"Pediatr Surg Int"},{"key":"B30","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1097\/MPG.0b013e3181e72c24","article-title":"Evaluation of esophageal motility using multichannel intraluminal impedance in healthy children and children with gastroesophageal reflux","volume":"52","author":"Di Pace","year":"2011","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B31","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/978-3-319-43268-7_28","article-title":"Esophageal atresia","volume-title":"Pediatric Neurogastroenterology","author":"Righini Grunder","year":"2017"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1016\/S0022-3468(98)90003-3","article-title":"Outcome of patients operated on for esophageal atresia: 30 years\u2019 experience","volume":"33","author":"Somppi","year":"1998","journal-title":"J Pediatr Surg"},{"key":"B33","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/s00383-002-0887-z","article-title":"Long-term evaluation of esophageal function in patients treated at birth for esophageal atresia","volume":"19","author":"Tomaselli","year":"2003","journal-title":"Pediatr Surg Int"},{"key":"B34","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/S0022-3468(86)80002-1","article-title":"Abnormal tracheal innervation in patients with esophageal atresia and tracheoesophageal fistula: study of the intrinsic tracheal nerve plexuses by a microdissection technique","volume":"21","author":"Nakazato","year":"1986","journal-title":"J Pediatr Surg"},{"key":"B35","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/S0022-3468(00)90209-4","article-title":"A histopathological study of esophageal atresia and tracheoesophageal fistula","volume":"35","author":"Dutta","year":"2000","journal-title":"J Pediatr Surg"},{"key":"B36","doi-asserted-by":"publisher","first-page":"695837","DOI":"10.1155\/2009\/695837","article-title":"Intramural ganglion structures in esophageal atresia: a morphologic and immunohistochemical study","volume":"2009","author":"Zuccarello","year":"2009","journal-title":"Int J Pediatr"},{"key":"B37","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1097\/MPG.0b013e3181dd9d40","article-title":"Reduction of interstitial cells of Cajal in esophageal atresia","volume":"51","author":"Midrio","year":"2010","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B38","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1007\/s00268-007-9070-y","article-title":"Reduced neuronal innervation in the distal end of the proximal esophageal atretic segment in cases of esophageal atresia with distal tracheoesophageal fistula","volume":"31","author":"Boleken","year":"2007","journal-title":"World J Surg"},{"key":"B39","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s00383-007-2032-5","article-title":"Intrinsic esophageal innervation in esophageal atresia without fistula","volume":"24","author":"Pederiva","year":"2008","journal-title":"Pediatr Surg Int"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1046\/j.1365-2168.1996.02337.x","article-title":"Anatomy of the extrinsic motor nerve supply to mobilized segments of the oesophagus disrupted by dissection during repair of oesophageal atresia with distal fistula","volume":"83","author":"Davies","year":"1996","journal-title":"Br J Surg"},{"key":"B41","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1016\/j.jpedsurg.2007.03.050","article-title":"The structural characteristics and expression of neuropeptides in the esophagus of patients with congenital esophageal atresia and tracheoesophageal fistula","volume":"42","author":"Li","year":"2007","journal-title":"J Pediatr Surg"},{"key":"B42","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1007\/s003830050500","article-title":"Abnormal enteric nerve morphology in atretic esophagus of fetal rats with adriamycin-induced esophageal atresia","volume":"15","author":"Cheng","year":"1999","journal-title":"Pediatr Surg Int"},{"key":"B43","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1097\/MPG.0000000000000667","article-title":"Esophageal dysmotility is present before surgery in isolated tracheoesophageal fistula","volume":"60","author":"Lemoine","year":"2015","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B44","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1007\/BF02412636","article-title":"Esophageal motility in an adult with a congenital H-type tracheoesophageal fistula","volume":"5","author":"Heitmiller","year":"1990","journal-title":"Dysphagia"},{"key":"B45","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1007\/BF01537117","article-title":"Effects of cisapride on distal esophageal motility in humans","volume":"34","author":"Corazziari","year":"1989","journal-title":"Dig Dis Sci"},{"key":"B46","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1097\/01.mcg.0000225542.03880.68","article-title":"Bethanechol improves smooth muscle function in patients with severe ineffective esophageal motility","volume":"41","author":"Agrawal","year":"2007","journal-title":"J Clin Gastroenterol"},{"key":"B47","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1016\/j.jpeds.2006.05.029","article-title":"Effect of baclofen on esophagogastric motility and gastroesophageal reflux in children with gastroesophageal reflux disease: a randomized controlled trial","volume":"149","author":"Omari","year":"2006","journal-title":"J Pediatr"},{"key":"B48","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/978-3-319-43268-7_44","article-title":"Drugs acting on the gut: prokinetics, antispasmodics, laxatives","volume-title":"Pediatric Neurogastroenterology","author":"Har","year":"2017"},{"key":"B49","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1097\/00005176-200501000-00013","article-title":"Esophageal motor activity in children with gastro-esophageal reflux disease and esophagitis","volume":"40","author":"Chitkara","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"B50","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1111\/nmo.12753","article-title":"High-resolution manometry in patients with eosinophilic esophagitis under topical steroid therapy\u2014a prospective observational study (HIMEOS-study)","volume":"28","author":"Nennstiel","year":"2016","journal-title":"Neurogastroenterol Motil"},{"key":"B51","doi-asserted-by":"publisher","first-page":"3050","DOI":"10.1038\/ajg.2009.543","article-title":"Esophageal dysmotility in children with eosinophilic esophagitis: a study using prolonged esophageal manometry","volume":"104","author":"Nurko","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"B52","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1055\/s-0035-1559818","article-title":"Dysphagia in children with esophageal atresia: current diagnostic options","volume":"25","author":"Rayyan","year":"2015","journal-title":"Eur J Pediatr Surg"}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fped.2017.00130\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,31]],"date-time":"2017-05-31T13:11:47Z","timestamp":1496236307000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fped.2017.00130\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,31]]},"references-count":52,"alternative-id":["10.3389\/fped.2017.00130"],"URL":"https:\/\/doi.org\/10.3389\/fped.2017.00130","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,31]]},"article-number":"130"}}