{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:09:26Z","timestamp":1790687366252,"version":"4.1.0"},"reference-count":79,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"DOI":"10.3389\/fped.2018.00276","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T14:23:32Z","timestamp":1538576612000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":56,"title":["Asthma: Differential Diagnosis and Comorbidities"],"prefix":"10.3389","volume":"6","author":[{"given":"Nicola","family":"Ullmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Mirra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Di Marco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martino","family":"Pavone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Porcaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Negro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Onofri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Cutrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,10,3]]},"reference":[{"key":"B1","unstructured":"Global Strategy for Asthma Management and Prevention2016"},{"key":"B2","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1089\/ped.2010.0021","article-title":"Severe asthma in children: insights from the National Heart, Lung, and Blood Institute's Severe Asthma Research Program","volume":"23","author":"Fitzpatrick","year":"2010","journal-title":"Pediatr Allergy Immunol Pulmonol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1183\/09031936.00202013","article-title":"International ERS\/ATS guidelines on definition, evaluation and treatment of severe asthma","volume":"43","author":"Chung","year":"2014","journal-title":"Eur Respir J"},{"key":"B4","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1111\/resp.13085","article-title":"Severe asthma in children","volume":"22","author":"Bush","year":"2017","journal-title":"Respirology"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e152","DOI":"10.3399\/bjgp16X683965","article-title":"Overdiagnosis of asthma in children in primary care: a retrospective analysis","volume":"66","author":"Looijmans-van den Akker","year":"2016","journal-title":"Br J Gen Pract"},{"key":"B6","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1001\/jama.2016.19627","article-title":"Canadian Respiratory Research Network. Reevaluation of diagnosis in adults with physician-diagnosed asthma","volume":"317","author":"Aaron","year":"2017","journal-title":"JAMA"},{"key":"B7","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1136\/thx.2010.153643","article-title":"Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome (U-BIOPRED) Consortium, Consensus Generation. Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI)","volume":"66","author":"Bel","year":"2011","journal-title":"Thorax"},{"key":"B8","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1136\/adc.75.6.489","article-title":"Clinical significance of cough and wheeze in the diagnosis of asthma","volume":"75","author":"Kelly","year":"1996","journal-title":"Arch Dis Child"},{"key":"B9","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1136\/adc.82.4.327","article-title":"What do parents of wheezy children understand by \u201cwheeze\u201d?","volume":"82","author":"Cane","year":"2000","journal-title":"Arch Dis Child"},{"key":"B10","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1081\/JAS-200038451","article-title":"Wheeze detection: recordings vs. assessment of physician and parent","volume":"41","author":"Levy","year":"2004","journal-title":"J Asthma"},{"key":"B11","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1136\/thoraxjnl-2014-205738","article-title":"Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population","volume":"70","author":"Johansson","year":"2015","journal-title":"Thorax"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2174\/1874306401711010001","article-title":"Analysis of the literature on chronic cough in children","volume":"11","author":"Bergamini","year":"2017","journal-title":"Open Respir Med J"},{"key":"B13","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/S1526-0550(02)00008-2","article-title":"Differential diagnosis of asthma","volume":"3","author":"Rosenthal","year":"2002","journal-title":"Paediatr Respir Rev"},{"key":"B14","doi-asserted-by":"publisher","first-page":"iv1","DOI":"10.1136\/thx.2008.097741","article-title":"British Thoracic Society, Scottish Intercollegiate Guidelines Network","volume":"63","year":"2008","journal-title":"Thorax"},{"key":"B15","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1111\/j.1398-9995.2012.02865.x","article-title":"International consensus on (ICON) pediatric asthma","volume":"67","author":"Papadopoulos","year":"2012","journal-title":"Allergy"},{"key":"B16","year":"2007","journal-title":"Guidelines for the Diagnosis and Management of Asthma"},{"key":"B17","first-page":"127","article-title":"Screening for childhood asthma using an exercise test","volume":"44","author":"Jones","year":"1994","journal-title":"Br J Gen Pract"},{"key":"B18","unstructured":"British Guideline on the Management of Asthma2016"},{"key":"B19","doi-asserted-by":"publisher","first-page":"e97","DOI":"10.1016\/j.lpm.2017.04.010","article-title":"The diagnosis of cystic fibrosis","author":"De Boeck","year":"2017","journal-title":"Presse Med"},{"key":"B20","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.prrv.2017.03.001","article-title":"Cystic fibrosis in the era of precision medicine","volume":"25","author":"Paranjape","year":"2018","journal-title":"Paediatr Respir Rev."},{"key":"B21","doi-asserted-by":"publisher","first-page":"j4574","DOI":"10.1136\/bmj.j4574","article-title":"Diagnosis and management of cystic fibrosis: summary of NICE guidance","volume":"359","author":"Villanueva","year":"2017","journal-title":"BMJ"},{"key":"B22","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1513\/AnnalsATS.201707-539OT","article-title":"Cystic fibrosis foundation pulmonary guidelines. Use of cystic fibrosis transmembrane conductance regulator modulator therapy in patients with cystic fibrosis","volume":"15","author":"Ren","year":"2018","journal-title":"Ann Am Thorac Soc"},{"key":"B23","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.rmed.2018.02.013","article-title":"A review of the etiology and clinical presentation of non-cystic fibrosis bronchiectasis: a tertiary care experienceis","volume":"137","author":"Satirer","year":"","journal-title":"Respir Med"},{"key":"B24","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s13052-017-0434-0","article-title":"A pediatric disease to keep in mind: diagnostic tools and management of bronchiectasis in pediatric age","volume":"43","author":"Gallucci","year":"2017","journal-title":"Ital J Pediatr."},{"key":"B25","doi-asserted-by":"publisher","first-page":"77","DOI":"10.3389\/fped.2014.00077","article-title":"Pulmonary manifestations of primary immunodeficiency disorders in children","volume":"2","author":"Jesena","year":"2014","journal-title":"Front Pediatr"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.4187\/respcare.04479","article-title":"Sinopulmonary complications in subjects with primary immunodeficiency","volume":"61","author":"Owayed","year":"2016","journal-title":"Respir Care"},{"key":"B27","doi-asserted-by":"publisher","first-page":"231","DOI":"10.18176\/jiaci.0166","article-title":"Infectiousand noninfectious pulmonary complications in patients with primary immunodeficiency disorders","volume":"27","author":"Yazdani","year":"2017","journal-title":"J Invest Allergol Clin Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1513\/pats.201103-024SD","article-title":"Update of respiratory tract disease in children with primary ciliary dyskinesia","volume":"8","author":"Sagel","year":"2011","journal-title":"Proc Am Thorac Soc"},{"key":"B29","first-page":"1","article-title":"Asthma is associated with increased susceptibility to infection","volume":"106","author":"Patella","year":"2015","journal-title":"Miner Med"},{"key":"B30","doi-asserted-by":"publisher","first-page":"135","DOI":"10.3389\/fped.2017.00135","article-title":"Primary ciliary dyskinesia: an update on clinical aspects, genetics, diagnosis, and future treatment strategies","volume":"5","author":"Mirra","year":"2017","journal-title":"Front Pediatr"},{"key":"B31","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1183\/09031936.00032610","article-title":"Choice of nasal nitric oxide technique as first-line test for primary ciliary dyskinesia","volume":"37","author":"Marthin","year":"2011","journal-title":"Eur Respir J"},{"key":"B32","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1183\/13993003.00909-2016","article-title":"Diagnostic testing in primary ciliary dyskinesia","volume":"48","author":"Lucas","year":"2016","journal-title":"Eur Respir J"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1602139","DOI":"10.1183\/13993003.02139-2016","article-title":"ERS statement on protracted bacterial bronchitis in children","volume":"50","author":"Kantar","year":"2017","journal-title":"Eur Respir J"},{"key":"B34","doi-asserted-by":"publisher","first-page":"7","DOI":"10.4103\/atm.ATM_12_17","article-title":"An underestimated cause of chronic cough: the protracted bacterial bronchitis","volume":"13","author":"Di Filippo","year":"2018","journal-title":"Ann Thorac Med"},{"key":"B35","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1002\/ppul.23351","article-title":"Protracted bacterial bronchitis: the last decade and the road ahead","volume":"51","author":"Chang","year":"2016","journal-title":"Pediatr Pulmonol"},{"key":"B36","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1136\/thoraxjnl-2013-204880","article-title":"A young girl with apparent treatment-resistant asthma treated at Bambino Ges\u00f9 children's hospital","volume":"69","author":"Petreschi","year":"2014","journal-title":"Thorax"},{"key":"B37","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.cppeds.2018.03.002","article-title":"Laryngomalacia, tracheomalacia and bronchomalacia","volume":"48","author":"Hysinger","year":"2018","journal-title":"Curr Probl Pediatr Adolesc Health Care"},{"key":"B38","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1053\/j.sempedsurg.2016.02.008","article-title":"Pediatric tracheomalacia","volume":"25","author":"Fraga","year":"2016","journal-title":"Semin Pediatr Surg"},{"key":"B39","doi-asserted-by":"publisher","first-page":"3391","DOI":"10.1378\/chest.128.5.3391","article-title":"Tracheomalacia and bronchomalacia in children: incidence and patient characteristics","volume":"128","author":"Boogaard","year":"2005","journal-title":"Chest"},{"key":"B40","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/ppul.23831","article-title":"Dynamic expiratory CT: an effective non-invasive diagnostic exam for fragile children with suspected tracheo-bronchomalacia","volume":"53","author":"Ullmann","year":"2018","journal-title":"Pediatr Pulmonol"},{"key":"B41","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1183\/09031936.00104809","article-title":"Problematic severe asthma in children, not one problem but many: a GA2LEN initiative","volume":"36","author":"Hedlin","year":"2010","journal-title":"Eur Respir J"},{"key":"B42","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1080\/13548506.2013.806814","article-title":"Psychological distress in asthma and allergy: the v\u00e4sterbotten environmental health study","volume":"19","author":"Lind","year":"2014","journal-title":"Psychol Health Med"},{"key":"B43","doi-asserted-by":"publisher","first-page":"S136","DOI":"10.1016\/j.jaci.2011.12.987","article-title":"Mediators of asthma outcomes","volume":"129","author":"Rand","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"B44","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.jad.2015.09.040","article-title":"Association of asthma and anxiety: a nationwide population-based study in Taiwan","volume":"189","author":"Lee","year":"2016","journal-title":"J Affect Disord"},{"key":"B45","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s40733-015-0009-z","article-title":"Vocal cord dysfunction: a review","volume":"1","author":"Dunn","year":"2015","journal-title":"Asthma Res Pract"},{"key":"B46","doi-asserted-by":"publisher","first-page":"123","DOI":"10.2147\/JAA.S129159","article-title":"Managing the pediatric patient with refractory asthma: a multidisciplinary approach","volume":"10","author":"Cook","year":"2017","journal-title":"J Asthma Allergy"},{"key":"B47","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1183\/09031936.00091410","article-title":"PSACI (Problematic Severe Asthma in Childhood Initiative) group. Assessment of problematic severe asthma in children","volume":"37","author":"L\u00f8drup Carlsen","year":"2011","journal-title":"Eur Respir J"},{"key":"B48","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1542\/peds.2007-0078","article-title":"Pseudo-asthma: when cough, wheezing, and dyspnea are not asthma","volume":"120","author":"Weinberger","year":"2007","journal-title":"Pediatrics"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1183\/09031936.00130212","article-title":"Dysfunctional breathing in children with asthma: a rare but relevant comorbidity","volume":"41","author":"de Groot","year":"2013","journal-title":"Eur Respir J."},{"key":"B50","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.prrv.2010.07.005","article-title":"Post infectious bronchiolitis obliterans in children","volume":"11","author":"Fischer","year":"2010","journal-title":"Paediatr Respir Rev"},{"key":"B51","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1016\/S0140-6736(10)61054-9","article-title":"Management of severe asthma in children","volume":"376","author":"Bush","year":"2010","journal-title":"Lancet"},{"key":"B52","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s12887-018-1019-9","article-title":"Pediatric severe asthma: a case series report and perspectives on anti-IgE treatment","volume":"18","author":"Mirra","year":"2018","journal-title":"BMC Pediatr"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e113996","DOI":"10.1371\/journal.pone.0113996","article-title":"Overweight\/obesity and respiratory and allergic disease in children: international study of asthma and allergies in childhood (ISAAC) phase two","volume":"9","author":"Weinmayr","year":"2014","journal-title":"PLoS ONE"},{"key":"B54","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/j.jaci.2010.12.010","article-title":"Decreased response to inhaled steroids in overweight and obese asthmatic children","volume":"127","author":"Forno","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"B55","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1542\/peds.2007-0409","article-title":"Childhood overweight increases hospital admission rates for asthma","volume":"120","author":"Carroll","year":"2007","journal-title":"Pediatrics"},{"key":"B56","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1016\/S2213-2600(16)30048-0","article-title":"Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts","volume":"4","author":"Peters","year":"2016","journal-title":"Lancet Respir Med."},{"key":"B57","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.mayocp.2016.09.017","article-title":"Review of childhood obesity: from epidemiology, etiology, and comorbidities to clinical assessment and treatment","volume":"92","author":"Kumar","year":"2017","journal-title":"Mayo Clin Proc"},{"key":"B58","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.anai.2018.02.005","article-title":"Age-related prevalence of chronic rhinosinusitis and nasal polyps and their relationships with asthma onset","volume":"120","author":"Won","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1002\/alr.21674","article-title":"Prevalence of confirmed asthma varies in chronic rhinosinusitis subtypes","volume":"6","author":"Promsopa","year":"2016","journal-title":"Int Forum Allergy Rhinol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1186\/1471-2466-6-S1-S3","article-title":"Survey on the impact of comorbid allergic rhinitis in patients with asthma","volume":"6","author":"Valovirta","year":"2006","journal-title":"BMC Pulm Med"},{"key":"B61","doi-asserted-by":"publisher","first-page":"205","DOI":"10.2500\/ajra.2011.25.3613","article-title":"Association between severity of asthma and degree of chronic rhinosinusitis","volume":"25","author":"Lin","year":"2011","journal-title":"Am J Rhinol Allergy"},{"key":"B62","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1136\/thoraxjnl-2011-201168","article-title":"Allergic rhinitis is associated with poor asthma control in children with asthma","volume":"67","author":"de Groot","year":"2012","journal-title":"Thorax"},{"key":"B63","doi-asserted-by":"publisher","first-page":"428","DOI":"10.2500\/ajr.2007.21.3060","article-title":"The role of anti-IgE immunoglobulin therapy in nasal polyposis: a pilot study","volume":"21","author":"Penn","year":"2007","journal-title":"Am J Rhinol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.jaci.2012.07.047","article-title":"Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma","volume":"131","author":"Gevaert","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"B65","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1164\/rccm.201602-0419OC","article-title":"Inflammatory and co-morbid features of patients with severe asthma and frequent exacerbations","volume":"195","author":"Denlinger","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"B66","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001496","article-title":"Gastro-oesophageal reflux treatment for asthma in adults and children","author":"Gibson","year":"2003","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"B67","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1001\/jama.2011.2035","article-title":"Lansoprazole for children with poorly controlled asthma: a randomized controlled trial","volume":"307","author":"Holbrook","year":"2012","journal-title":"JAMA"},{"key":"B68","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1586\/17474124.2015.1042861","article-title":"Extra-esophageal gastroesophageal reflux disease and asthma: understanding this interplay","volume":"9","author":"Naik","year":"2015","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1067\/mai.2003.1569","article-title":"Food allergy as a risk factor for life-threatening asthma in childhood: a case-controlled study","volume":"112","author":"Roberts","year":"2003","journal-title":"J Allergy Clin Immunol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1111\/apa.13059","article-title":"Getting the basics right resolves most cases of uncontrolled and problematic asthma","volume":"104","author":"de Groot","year":"2015","journal-title":"Acta Paediatr"},{"key":"B71","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1016\/j.jaci.2004.01.778","article-title":"The nat-ural course of atopic dermatitis from birth to age 7 years and the association with asthma","volume":"113","author":"Illi","year":"2004","journal-title":"J Allergy Clin Immunol."},{"key":"B72","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1542\/peds.111.S3.1625","article-title":"Respiratory manifestations of food allergy","volume":"111","author":"James","year":"2003","journal-title":"Pediatrics"},{"key":"B73","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/0091-6749(89)90103-6","article-title":"The natural history of peanut allergy","volume":"83","author":"Bock","year":"1989","journal-title":"J Allergy Clin Immunol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.jaci.2011.01.031","article-title":"Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy","volume":"127","author":"Brown","year":"2011","journal-title":"J Allergy Clin Immunol."},{"key":"B75","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1111\/j.1398-9995.2011.02765.x","article-title":"Cutaneous lymphocyte antigen and alpha4-beta7 T-lymphocyte responses are associated with peanut allergy and tolerance in children","volume":"67","author":"Chan","year":"2012","journal-title":"Allergy"},{"key":"B76","doi-asserted-by":"publisher","first-page":"34","DOI":"10.3389\/fped.2016.00034","article-title":"Asthma and food allergy in children: is there a connection or interaction?","volume":"4","author":"Caffarelli","year":"2016","journal-title":"Front Pediatr."},{"key":"B77","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s11882-018-0785-7","article-title":"SLIT's prevention of the allergic march","volume":"18","author":"Porcaro","year":"2018","journal-title":"Curr Allergy Asthma Rep"},{"key":"B78","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1080\/17476348.2016.1191355","article-title":"How to manage a child with difficult asthma?","volume":"10","author":"Saglani","year":"2016","journal-title":"Expert Rev Respir Med"},{"key":"B79","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1183\/20734735.008914","article-title":"The national review of asthma deaths: what did we learn and what needs to change?","volume":"11","author":"Levy","year":"2015","journal-title":"Breathe (Sheff)."}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fped.2018.00276\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T05:51:50Z","timestamp":1662184310000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fped.2018.00276\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,3]]},"references-count":79,"alternative-id":["10.3389\/fped.2018.00276"],"URL":"https:\/\/doi.org\/10.3389\/fped.2018.00276","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,3]]},"article-number":"276"}}