{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T23:06:41Z","timestamp":1777763201735,"version":"3.51.4"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T00:00:00Z","timestamp":1576195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"DOI":"10.3389\/fped.2019.00503","type":"journal-article","created":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T04:33:36Z","timestamp":1576211616000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":20,"title":["Oral Dexamethasone vs. Oral Prednisone for Children With Acute Asthma Exacerbations: A Systematic Review and Meta-Analysis"],"prefix":"10.3389","volume":"7","author":[{"given":"Jienan","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingqing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"SC01","DOI":"10.7860\/JCDR\/2018\/30505.11171","article-title":"Single-dose oral dexamethasone compared with three day course of oral prednisolone in children with moderate exacerbation of asthma-a pilot double-blinded randomised controlled trial","volume":"12","author":"Prasannavenkatesh","year":"2018","journal-title":"J Clin Diag Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/01.pec.0000092585.40174.f6","article-title":"Corticosteroids in acute asthma: past, present, and future","volume":"19","author":"Scarfone","year":"2003","journal-title":"Pediatr Emerg Care."},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011801.pub2","article-title":"Different oral corticosteroid regimens for acute asthma","author":"Normansell","year":"2016","journal-title":"Cochrane Database Syst Rev."},{"key":"B4","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1542\/peds.2013-2273","article-title":"Dexamethasone for acute asthma exacerbations in children: a meta-analysis","volume":"133","author":"Keeney","year":"2014","journal-title":"Pediatrics."},{"key":"B5","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.annemergmed.2014.05.023","article-title":"Is dexamethasone as effective as prednisone or prednisolone in the management of pediatric asthma exacerbations?","volume":"65","author":"Schwarz","year":"2015","journal-title":"Ann Emerg Med."},{"key":"B6","unstructured":"31273040British Guideline on the Management of Asthma2019"},{"key":"B7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1067\/mpd.2001.115021","article-title":"Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma","volume":"139","author":"Qureshi","year":"2001","journal-title":"J Pediatr."},{"key":"B8","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1097\/01.pec.0000144914.78124.6f","article-title":"Adherence of pediatric asthma patients with oral corticosteroid prescriptions following pediatric emergency department visit or hospitalization","volume":"20","author":"Butler","year":"2004","journal-title":"Pediatr Emerg Care."},{"key":"B9","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1097\/PEC.0b013e318128f821","article-title":"Randomized trial of single-dose intramuscular dexamethasone compared with prednisolone for children with acute asthma","volume":"23","author":"Gordon","year":"2007","journal-title":"Pediatr Emerg Care."},{"key":"B10","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1136\/adc.84.4.347","article-title":"Short report: crushed prednisolone tablets or oral solution for acute asthma?","volume":"84","author":"Lucas-Bouwman","year":"2001","journal-title":"Arch Dis Child."},{"key":"B11","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1067\/mpd.2000.103353","article-title":"A single dose of intramuscularly administered dexamethasone acetate is as effective as oral prednisone to treat asthma exacerbations in young children","volume":"136","author":"Gries","year":"2000","journal-title":"J Pediatr."},{"key":"B12","doi-asserted-by":"publisher","first-page":"419","DOI":"10.3109\/02770909709055384","article-title":"Symptomatic improvement following emergency department management of asthma: a pilot study of intramuscular dexamethasone versus oral prednisone","volume":"34","author":"Klig","year":"1997","journal-title":"J Asthma."},{"key":"B13","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.annemergmed.2015.08.001","article-title":"A randomized trial of single-dose oral dexamethasone versus multidose prednisolone for acute exacerbations of asthma in children who attend the emergency department","volume":"67","author":"Cronin","year":"2016","journal-title":"Ann Emerg Med."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"key":"B15","unstructured":"HigginsJ\n            GreenS\n          Cochrane Handbook for Systemic Reviews of Interventions Version 52011"},{"key":"B16","unstructured":"Cochrane statistical methods group and the cochrane bias methods group\n            HigginsJ\n            AltmanD\n            SterneJ\n          Cochrane Handbook for Systemic Reviews of Interventions2011"},{"key":"B17","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1046\/j.1365-2648.2002.02177.x","article-title":"Power dressing and meta-analysis: incorporating power analysis into meta-analysis","volume":"38","author":"Muncer","year":"2002","journal-title":"J Adv Nurs."},{"key":"B18","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1097\/01.pec.0000248683.09895.08","article-title":"Single-dose oral dexamethasone in the emergency management of children with Exacerbations of Mild to Moderate Asthma","volume":"22","author":"Altamimi","year":"2006","journal-title":"Pediatr Emerg Care."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1136\/ejhpharm-2018-001707","article-title":"Two regimens of dexamethasone versus prednisolone for acute exacerbations in asthmatic Egyptian children","author":"Elkharwili","year":"2018","journal-title":"Eur J Hosp Pharm."},{"key":"B20","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1177\/0009922808316988","article-title":"A comparison of oral dexamethasone with oral prednisone in pediatric asthma exacerbations treated in the emergency department","volume":"47","author":"Greenberg","year":"2008","journal-title":"Clin Pediatr."},{"key":"B21","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.jpeds.2017.08.030","article-title":"Randomized trial of dexamethasone versus prednisone for children with acute asthma exacerbations","volume":"191","author":"Paniagua","year":"2017","journal-title":"J Pediatr."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1001\/archpedi.155.10.1111","article-title":"Corticosteroid prescription filling for children covered by medicaid following an emergency department visit or a hospitalization for asthma","volume":"155","author":"Cooper","year":"2001","journal-title":"Arch Pediatr Adolesc Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/S0196-0644(95)70118-4","article-title":"Nebulized dexamethasone versus oral prednisone in the emergency treatment of asthmatic children","volume":"26","author":"Scarfone","year":"1995","journal-title":"Ann Emerg Med."},{"key":"B24","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1097\/TME.0000000000000109","article-title":"Treating adult asthma exacerbations with a 2-day course of dexamethasone in the emergency department","volume":"38","author":"Evans","year":"2016","journal-title":"Adv Emerg Nurs J."},{"key":"B25","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.annemergmed.2011.01.004","article-title":"Two days of dexamethasone versus 5 days of prednisone in the treatment of acute asthma: a randomized controlled trial","volume":"58","author":"Kravitz","year":"2011","journal-title":"Ann Emerg Med."},{"key":"B26","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.annemergmed.2016.03.017","article-title":"A randomized controlled non-inferiority trial of single dose of oral dexamethasone versus 5 days of oral prednisone in acute adult asthma","volume":"68","author":"Rehrer","year":"2016","journal-title":"Ann Emerg Med."},{"key":"B27","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/ppul,0.20031","article-title":"Factors associated with short-term clinical outcomes after acute treatment of asthma in a pediatric emergency department","volume":"38","author":"Benito-Fern\u00e1ndez","year":"2004","journal-title":"Pediatr Pulmonol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1634\/theoncologist.2017-0129","article-title":"Antiemetic corticosteroid rotation from dexamethasone to methylprednisolone to prevent dexamethasone-induced hiccup in cancer patients treated with chemotherapy: a randomized, single-blind, crossover phase III trial","volume":"22","author":"Go","year":"2017","journal-title":"Oncologist."},{"key":"B29","first-page":"e95","article-title":"A palatability study of a flavored dexamethasone preparation versus prednisolone liquid in children","volume":"15","author":"Hames","year":"2008","journal-title":"Can J Clin Pharmacol."}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fped.2019.00503\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T04:33:39Z","timestamp":1576211619000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fped.2019.00503\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,13]]},"references-count":29,"alternative-id":["10.3389\/fped.2019.00503"],"URL":"https:\/\/doi.org\/10.3389\/fped.2019.00503","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,13]]},"article-number":"503"}}