{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:49:31Z","timestamp":1761709771491,"version":"3.41.2"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T00:00:00Z","timestamp":1599523200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"DOI":"10.3389\/fped.2020.00555","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T07:07:15Z","timestamp":1599548835000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Isoprostanes as Biomarker for Patent Ductus Arteriosus in Preterm Infants"],"prefix":"10.3389","volume":"8","author":[{"given":"Caterina","family":"Coviello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Luisa","family":"Tataranno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iuri","family":"Corsini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Leonardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariangela","family":"Longini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Bazzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Buonocore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Dani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,8]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1542\/peds.2009-3506","article-title":"Patent ductus arteriosus of the preterm infant","volume":"125","author":"Hamrick","year":"2010","journal-title":"Pediatrics."},{"key":"B2","doi-asserted-by":"publisher","first-page":"F474","DOI":"10.1136\/archdischild-2014-306214","article-title":"Reflections of the changes in patent ductus arteriosus management during the last 10 years","volume":"101","author":"El-Khuffash","year":"2016","journal-title":"Arch Dis Child Fetal Neonatal Ed."},{"key":"B3","doi-asserted-by":"publisher","first-page":"F235","DOI":"10.1136\/adc.2004.057638","article-title":"Is surgical ligation of patent ductus arteriosus necessary? The Western Australian experience of conservative management","volume":"90","author":"Brooks","year":"2005","journal-title":"Arch Dis Child Fetal Neonatal Ed."},{"key":"B4","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1038\/jp.2011.102","article-title":"What happens when the patent ductus arteriosus is treated less aggressively in very low birth weight infants?","volume":"32","author":"Kaempf","year":"2012","journal-title":"J Perinatol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.jpeds.2017.03.021","article-title":"Prophylactic indomethacin compared with delayed conservative management of the patent ductus arteriosus in extremely preterm infants, effects on neonatal outcomes","volume":"187","author":"Liebowitz","year":"2017","journal-title":"J Pediatr."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1016\/j.jpeds.2015.03.012","article-title":"Association between hemodynamically significant patent ductus arteriosus and bronchopulmonary dysplasia","volume":"166","author":"Schena","year":"2015","journal-title":"J Pediatr."},{"key":"B7","doi-asserted-by":"publisher","first-page":"S46","DOI":"10.1038\/s41390-018-0077-x","article-title":"Application of NPE in the assessment of a patent ductus arteriosus","volume":"84","author":"van Laere","year":"2018","journal-title":"Pediatr Res."},{"key":"B8","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1001\/jamapediatrics.2015.0987","article-title":"Diagnosis, evaluation, and management of patent Ductus Arteriosus in preterm neonates","volume":"169","author":"Jain","year":"2015","journal-title":"JAMA Pediatr."},{"key":"B9","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.cbpa.2011.04.010","article-title":"Contractile effects of 15-E2t-isoprostane and 15-F2t-isoprostane on chicken embryo ductus arteriosus","volume":"159","author":"van der Sterren","year":"2011","journal-title":"Comp Biochem Physiol A Mol Integr Physiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1038\/pr.2012.58","article-title":"Isoprostanes as physiological mediators of transition to newborn life, novel mechanisms regulating patency of the term and preterm ductus arteriosus","volume":"72","author":"Chen","year":"2012","journal-title":"Pediatr Res."},{"key":"B11","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s00467-010-1651-6","article-title":"Isoprostane levels in urine of preterm newborns treated with ibuprofen for patent ductus arteriosus closure","volume":"26","author":"Longini","year":"2011","journal-title":"Pediatr Nephrol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"S114","DOI":"10.3109\/14767058.2012.664856","article-title":"Development of a fast and simple lc-ms\/ms method for measuring the f2-isoprostanes in newborns","volume":"25","author":"Casetta","year":"2012","journal-title":"J Matern Fetal Neonatal Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1055\/s-0032-1324702","article-title":"Relationship between platelet count and volume and spontaneous and pharmacological closure of ductus arteriosus in preterm infants","volume":"30","author":"Dani","year":"2013","journal-title":"Am J Perinatol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"F197","DOI":"10.1136\/fn.81.3.F197","article-title":"Echocardiographic flow pattern of patent ductus arteriosus: a guide to indomethacin treatment in premature infants","volume":"81","author":"Su","year":"1999","journal-title":"Arch Dis Child Fetal Neonatal Ed."},{"key":"B15","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1186\/1471-2431-13-207","article-title":"Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study","volume":"13","author":"Onland","year":"2013","journal-title":"BMC Pediatr."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00000658-197801000-00001","article-title":"Neonatal necrotizing enterocolitis: therapeutic decisions based upon clinical staging","volume":"187","author":"Bell","year":"1978","journal-title":"Ann Surg."},{"key":"B17","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of the sub-ependymal intraventricular hemorrhage: a study of infants weighing less than 1500 grams","volume":"92","author":"Papile","year":"1978","journal-title":"J Pediatr."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0166-4328(05)80189-5","article-title":"The spectrum of leukomalacia using cranial ultrasounds","volume":"49","author":"De Vries","year":"1992","journal-title":"Behav Brain Res."},{"key":"B19","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1054\/plef.2001.0295","article-title":"F2-Isoprostanes and prostaglandin F2\u03b1 metabolite excretion rate and day to day variation in healthy humans","volume":"65","author":"Helmersson","year":"2001","journal-title":"Prostaglandins Leukot Essent Fatty Acids."},{"key":"B20","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.freeradbiomed.2004.06.007","article-title":"Plasma F2-isoprostanes are elevated in newborns and inversely correlated to gestational age","volume":"37","author":"Comporti","year":"2004","journal-title":"Free Radic Biol Med."},{"key":"B21","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3109\/10715769009145692","article-title":"Spin trapping of ibuprofen radicals: evidence that ibuprofen is a hydroxyl radical scavenger","volume":"9","author":"Hamburger","year":"1990","journal-title":"Free Radic Res Commun."},{"key":"B22","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/1742-2094-1-20","article-title":"Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo","volume":"1","author":"Milatovic","year":"2004","journal-title":"J Neuroinflammation."}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fped.2020.00555\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T07:07:16Z","timestamp":1599548836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fped.2020.00555\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,8]]},"references-count":22,"alternative-id":["10.3389\/fped.2020.00555"],"URL":"https:\/\/doi.org\/10.3389\/fped.2020.00555","relation":{},"ISSN":["2296-2360"],"issn-type":[{"type":"electronic","value":"2296-2360"}],"subject":[],"published":{"date-parts":[[2020,9,8]]},"article-number":"555"}}