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Practice variations still exist within sub-specialties and centers. This article briefly summarizes the history, embryology and histology of the PDA. It also succinctly discusses the hemodynamic significance of a PDA which builds the framework to review all the available literature on PDA closure in premature infants, though not a paradigm shift just yet; it introduces transcatheter PDA closure (TCPC) as a possible armament to the clinician for this age-old problem.<\/jats:p>","DOI":"10.3389\/fped.2020.590578","type":"journal-article","created":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T10:51:00Z","timestamp":1613040660000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":68,"title":["Management of Patent Ductus Arteriosus in Premature Infants in 2020"],"prefix":"10.3389","volume":"8","author":[{"given":"Sarah","family":"Parkerson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjit","family":"Philip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Talati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam","family":"Sathanandam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,2,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1161\/01.CIR.43.3.323","article-title":"Congenital heart disease in 56,109 births: incidence and natural history","volume":"43","author":"Mitchell","year":"1971","journal-title":"Circulation."},{"key":"B2","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1111\/chd.12729","article-title":"Practice variation in the management of patent ductus arteriosus in extremely low birth weight infants in the United States: survey results among cardiologists and neonatologists","volume":"14","author":"Sathanandam","year":"2019","journal-title":"Congenit Heart Dis"},{"key":"B3","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.jpeds.2006.03.015","article-title":"Treatment to prevent patency of the ductus arteriosus: beneficial or harmful?","volume":"148","author":"Bose","year":"2006","journal-title":"J Pediatr."},{"key":"B4","doi-asserted-by":"publisher","first-page":"e20153730","DOI":"10.1542\/peds.2015-3730","article-title":"Committee of the fetus and newborn. 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