{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:01:06Z","timestamp":1789286466923,"version":"build-2803163510"},"reference-count":69,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T00:00:00Z","timestamp":1628812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Since its clearance for use throughout the world, capsule endoscopy (CE) has become an important diagnostic tool, helping us to understand and document both normal and abnormal findings in the small intestine, especially in children, since CE usually can be employed without sedation or radiation. The indications in children and adults are similar, though their relative frequencies are different, with evaluation of potential and known inflammatory bowel disease the most common in the pediatric population, with CE also yielding increased diagnostic certainty compared to radiographic studies and surrogate biomarkers. Newer capsules now create opportunities to expand that understanding and our practices so that we can learn when and how to employ CE and pan-enteric CE to better monitor and guide therapy. It will take further studies to determine the best uses for CE and how to select the appropriate candidates, especially with ongoing concern about capsule ingestion vs. placement, the potential for capsule retention (particularly in known Crohn's disease), still elusive optimal methods for bowel cleansing, and the most meaningful scoring for research and clinical use.<\/jats:p>","DOI":"10.3389\/fped.2021.664722","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T10:12:55Z","timestamp":1628849575000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["Capsule Endoscopy in Children"],"prefix":"10.3389","volume":"9","author":[{"given":"Stanley A.","family":"Cohen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Oliva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,8,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1067\/mge.2000.110204","article-title":"The development of the swallowable video capsule (M2A)","volume":"52","author":"Meron","year":"2000","journal-title":"Gastrointest Endosc."},{"key":"B2","unstructured":"2009"},{"key":"B3","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.gie.2006.01.014","article-title":"ASGE Technology Status Evaluation Report: wireless capsule endoscopy","volume":"63","author":"Mishkin","year":"2006","journal-title":"Gastro Endosc."},{"key":"B4","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1055\/s-0034-1391855","article-title":"Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline","volume":"47","author":"Pennazio","year":"2015","journal-title":"Endoscopy."},{"key":"B5","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1055\/s-0041-102450","article-title":"Small intestinal capsule endoscopy: recommendations and limitations of the new ESGE-guideline 2015","volume":"13","author":"Escher","year":"2015","journal-title":"Dtsch Med Wochenschr."},{"key":"B6","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.gie.2009.09.031","article-title":"Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review","volume":"71","author":"Liao","year":"2010","journal-title":"Gastrointest Endosc."},{"key":"B7","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.gastrohep.2012.10.007","article-title":"The potential applications of capsule endoscopy in pediatric compared to adult patients","volume":"9","author":"Cohen","year":"2013","journal-title":"Gastroenterol Hepatol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.cgh.2011.03.025","article-title":"Use of capsule endoscopy in diagnosis and management of pediatric patients, based on meta-analysis","volume":"9","author":"Cohen","year":"2011","journal-title":"Clin Gastroenterol Hepatol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1097\/MPG.0b013e31822c81fd","article-title":"Pediatric capsule endoscopy: a single center, 5 year retrospective review of small bowel and patency capsules","volume":"54","author":"Cohen","year":"2012","journal-title":"JPGN."},{"key":"B10","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10620-011-1894-5","article-title":"Small bowel capsule endoscopy impacts diagnosis and management of pediatric inflammatory bowel disease: a prospective study","volume":"57","author":"Gralnek","year":"2012","journal-title":"Digest Dis Scien."},{"key":"B11","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1007\/s00535-010-0209-5","article-title":"Wireless capsule endoscopy in pediatric patients: the first series from Japan","volume":"45","author":"Tokuhara","year":"2010","journal-title":"J Gastroenterol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/S1542-3565(04)00715-3","article-title":"Araujo Sant'Anna AM, Dubois J, Miron MC, Seidman EG. 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