{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T19:12:22Z","timestamp":1775157142902,"version":"3.50.1"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Ultrasonography (USG) has been described as an alternative diagnostic tool for malrotation that evaluates the orientation of the superior mesenteric vessels. However, literature concerning the management of patients who do not have abdominal symptoms is limited. We aimed to review the clinical course of infants showing abnormal orientation of the superior mesenteric vessels on USG who were asymptomatic at the time of diagnosis.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Seventy asymptomatic infants with abnormal orientation of the superior mesenteric vessels in a single center between 2014 and 2018 were retrospectively analyzed.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The 70 patients, 21 underwent upper gastrointestinal series (UGIS) and 11 underwent abdominal surgery for other surgical conditions. Among the 32 (45.7%) patients who underwent UGIS or abdominal surgery, 11 were proven to have malrotation. Of the 38 (54.3%) patients who did not undergo UGIS or abdominal surgery, six patients were too unstable to undergo UGIS, five died due to cardiac complications, and the remaining patient developed midgut volvulus and died 3 days after emergency surgery. The remaining 32 patients who did not undergo UGIS or abdominal surgery were discharged without additional tests, and all were asymptomatic until their last follow-up. In the multivariate analysis, history of heart surgery and the presence of more than three anomalies were significantly associated with malrotation.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> A significant number of malrotation were diagnosed in asymptomatic infants with abnormal orientation of the superior mesenteric vessels on USG. Infants with major cardiac or multiple anomalies need special attention and should undergo UGIS in a promptly manner to confirm malrotation.<\/jats:p>","DOI":"10.3389\/fped.2021.665448","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T06:26:19Z","timestamp":1623392779000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Abnormal Orientation of the Superior Mesenteric Vessels Detected in Asymptomatic Infants: What Is Its Destiny?"],"prefix":"10.3389","volume":"9","author":[{"given":"Joonhyuk","family":"Son","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanghoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wontae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo-Min","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Yeon","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So-Young","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Hye","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong-Meen","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"825","DOI":"10.2214\/ajr.159.4.1529850","article-title":"Sonographic diagnosis of intestinal malrotation in infants: importance of the relative positions of the superior mesenteric vein and artery","volume":"1594","author":"Weinberger","year":"1992","journal-title":"Am J Roentgenol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e8287","DOI":"10.1097\/MD.0000000000008287","article-title":"The efficiency of sonography in diagnosing volvulus in neonates with suspected intestinal malrotation","volume":"96","author":"Zhang","year":"2017","journal-title":"Medicine"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.jpedsurg.2005.12.070","article-title":"Is ultrasonography a good screening test for intestinal malrotation?","volume":"41","author":"Orzech","year":"2006","journal-title":"J Pediatr Surg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"730","DOI":"10.4329\/wjr.v6.i9.730","article-title":"Malrotation: current strategies navigating the radiologic diagnosis of a surgical emergency","volume":"6","author":"Tackett","year":"2014","journal-title":"World J Radiol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1007\/s002470100434","article-title":"A normal sonogram does not exclude malrotation","volume":"31","author":"Ashley","year":"2001","journal-title":"Pediatr Radiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/BF02011604","article-title":"Midgut malrotation, the reliability of sonographic diagnosis","volume":"22","author":"Dufour","year":"1992","journal-title":"Pediatr Radiol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1016\/j.ejrad.2016.07.013","article-title":"Intestinal malrotation in patients with situs anomaly: implication of the relative positions of the superior mesenteric artery and vein","volume":"85","author":"Choi","year":"2016","journal-title":"Eur J Radiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s11894-016-0490-4","article-title":"Small bowel congenital anomalies: a review and update","volume":"18","author":"Morris","year":"2016","journal-title":"Curr Gastroenterol Rep"},{"key":"B9","first-page":"716","article-title":"Malrotation of the bowel in infants and children: a 15 year review","volume":"79","author":"Stewart","year":"1976","journal-title":"Surgery"},{"key":"B10","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.jpedsurg.2014.01.039","article-title":"Age at presentation of common pediatric surgical conditions: reexamining dogma","volume":"49","author":"Aboagye","year":"2014","journal-title":"J Pediatr Surg."},{"key":"B11","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/j.amjsurg.2007.08.035","article-title":"Jack Barney Award. 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