{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:20:45Z","timestamp":1790677245406,"version":"4.1.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:00:00Z","timestamp":1622160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p><jats:bold>Objectives:<\/jats:bold> To describe changes in the dispensation of 11 mandatory vaccines to infants in France during the COVID-19 pandemic in 2020, considering the priming doses and boosters separately.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> With data from the French national health database, all dispensations of priming doses and boosters of 11 mandatory vaccines [penta\/hexavalent, measles mumps rubella (MMR), meningococcal conjugate type-C (Men-C-C), 13-valent pneumococcal conjugate (PCV13)] for infants \u226424 months old were aggregated by 4-week periods in 2020. Expected counts in 2020 were estimated according to counts in 2019 weighted by a ratio considering the level of vaccine dispensation before the pandemic onset in 2020. Relative differences (RDs) and their 95% confidence intervals (CIs) were computed to compare the observed and expected counts during the first and second lockdown and the period in between.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> During the first 4 weeks of the first lockdown, as compared with the expected numbers, the observed priming dose counts substantially decreased [RD: from \u22125.7% (95% CI \u22126.1; \u22125.2) for penta\/hexavalent to \u221225.2% (95% CI \u221225.6; \u221224.8) for MMR], as did the booster counts [RD: from \u221215.3% (95% CI \u221215.9; \u221214.7) for penta\/hexavalent to \u221220.7% (95% CI \u221221.3; \u221220.2) for Men-C-C]. Counts for priming doses and boosters remained slightly below the expected numbers after the lockdown. During 2020, MMR priming doses and the Men-C-C booster had the greatest shortfalls (<jats:italic>N<\/jats:italic> = 84,893 and 72,500, respectively).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> This study provides evidence of a lack of vaccination catch-up after the first lockdown and a persistent shortfall in infant vaccination after the first 10 months of the COVID-19 pandemic in France, especially for the MMR priming doses and Men-C-C booster.<\/jats:p>","DOI":"10.3389\/fped.2021.666848","type":"journal-article","created":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T04:47:31Z","timestamp":1622177251000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":32,"title":["Mandatory Infant Vaccinations in France During the COVID-19 Pandemic in 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