{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T16:45:56Z","timestamp":1790441156781,"version":"4.1.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    To review the literature related to bronchopulmonary dysplasia in extremely pre-mature infants, summarize research direction, and report trends.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    CiteSpace is a Java application which supports visual exploration with knowledge discovery in bibliographic databases. Relevant articles from 2008 to 2020 were retrieved from the Web of Science Core Collection database, and we extracted the following data: title, abstract, year, keywords, author, organization, journal and cited literature. We downloaded the data into CiteSpace (version 5.7.R3) to summarize countries, institutions, journals, and authors. We visualized the data with a knowledge map, collaborative network analysis, cluster analysis, and burst keyword analysis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    We identified 610 articles on bronchopulmonary dysplasia in extremely pre-mature infants. The United States had the most articles on this topic (302 articles), followed by Canada (49 articles) and Germany (44 articles). The top three institutions, high-yield journals, and authors were all from the United States. The most common keywords were neurodevelopmental disorders, active perinatal care, mechanical ventilation, inflammation, pulmonary hypertension, low-dose hydrocortisone, development, and patent ductus arteriosus.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    This study illustrates the trends and frontiers in the study of bronchopulmonary dysplasia in extremely pre-mature infants. The current research direction is to identify the risk factors in developing bronchopulmonary dysplasia in extremely pre-mature infants.\n                  <\/jats:p>","DOI":"10.3389\/fped.2021.705033","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T09:01:43Z","timestamp":1629450103000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":38,"title":["Bibliometric Analysis of Bronchopulmonary Dysplasia in Extremely Premature Infants in the Web of Science Database Using CiteSpace Software"],"prefix":"10.3389","volume":"9","author":[{"given":"Qin","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Bo","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Mei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Ya","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,8,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1001\/jama.2015.10244","article-title":"Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012","volume":"314","author":"Stoll","year":"2015","journal-title":"JAMA."},{"key":"B2","doi-asserted-by":"publisher","first-page":"125627","DOI":"10.1016\/j.chemosphere.2019.125627","article-title":"Freshwater microplastics pollution: detecting and visualizing emerging trends based on Citespace II","volume":"245","author":"Yao","year":"2020","journal-title":"Chemosphere."},{"key":"B3","doi-asserted-by":"publisher","first-page":"5303","DOI":"10.1073\/pnas.0307513100","article-title":"Searching for intellectual turning points: progressive knowledge domain visualization","volume":"101","author":"Chen","year":"2004","journal-title":"Proc Natl Acad Sci USA."},{"key":"B4","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.intimp.2019.03.045","article-title":"Bibliometric analysis of global research on PD-1 and PD-L1 in the field of cancer","volume":"72","author":"Gao","year":"2019","journal-title":"Int Immunopharmacol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"5792","DOI":"10.3390\/ijerph110605792","article-title":"Global research on smoking and pregnancy-a scientometric and gender analysis","volume":"11","author":"Mund","year":"2014","journal-title":"Int J Environ Res Public Health."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1093\/aje\/kwr241","article-title":"The quality of modern cross-sectional ecologic studies: a bibliometric review","volume":"174","author":"Dufault","year":"2011","journal-title":"Am J Epidemiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"20409","DOI":"10.1007\/s11356-017-9711-0","article-title":"Research trends and hotspots related to ammonia oxidation based on bibliometric analysis","volume":"24","author":"Zheng","year":"2017","journal-title":"Environ Sci Pollut Res Int."},{"key":"B8","doi-asserted-by":"publisher","first-page":"2050312118800199","DOI":"10.1177\/2050312118800199","article-title":"Knowledge mapping of medication literacy study: a visualized analysis using CiteSpace","volume":"6","author":"Liang","year":"2018","journal-title":"SAGE Open Med."},{"key":"B9","first-page":"121","article-title":"Searching for clinical evidence in CiteSpace","volume":"2005","author":"Chen","year":"2005","journal-title":"AMIA Annu Symp Proc"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1016\/j.jpeds.2015.09.028","article-title":"A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge","volume":"167","author":"El-Khuffash","year":"2015","journal-title":"J Pediatr"},{"key":"B11","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1055\/s-0039-1697672","article-title":"Relationship between duration of infant exposure to a moderate-to-large patent ductus arteriosus shunt and the risk of developing bronchopulmonary dysplasia or death before 36 weeks","volume":"37","author":"Clyman","year":"2020","journal-title":"Am J Perinatol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/chd.12691","article-title":"Hemodynamically significant patent ductus arteriosus and the development of bronchopulmonary dysplasia","volume":"14","author":"Willis","year":"2019","journal-title":"Congenit Heart Dis."},{"key":"B13","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.jpeds.2018.09.012","article-title":"PDA-TOLERATE trial: an exploratory randomized controlled trial of treatment of moderate-to-large patent ductus arteriosus at 1 week of age","volume":"205","author":"Clyman","year":"2019","journal-title":"J Pediatr"},{"key":"B14","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1542\/peds.2004-2843","article-title":"Low-dose dexamethasone facilitates extubation among chronically ventilator-dependent infants: a multicenter, international, randomized, controlled trial","volume":"117","author":"Doyle","year":"2006","journal-title":"Pediatrics."},{"key":"B15","doi-asserted-by":"publisher","first-page":"CD001145","DOI":"10.1002\/14651858.CD001145.pub4","article-title":"Late (> 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants","volume":"10","author":"Doyle","year":"2017","journal-title":"Cochrane Database Syst Rev."},{"key":"B16","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1093\/pch\/17.10.573","article-title":"Postnatal corticosteroids to treat or prevent chronic lung disease in preterm infants","volume":"17","author":"Jefferies","year":"2012","journal-title":"Paediatr Child Health."},{"key":"B17","doi-asserted-by":"publisher","first-page":"2112","DOI":"10.1056\/NEJMoa054065","article-title":"Caffeine therapy for apnea of prematurity","volume":"354","author":"Schmidt","year":"2006","journal-title":"N Engl J Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1056\/NEJMoa073679","article-title":"Long-term effects of caffeine therapy for apnea of prematurity","volume":"357","author":"Schmidt","year":"2007","journal-title":"N Engl J Med."},{"key":"B19","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1001\/jamapediatrics.2014.2223","article-title":"Association of early caffeine administration and neonatal outcomes in very preterm neonates","volume":"169","author":"Lodha","year":"2015","journal-title":"JAMA Pediatr."},{"key":"B20","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jpeds.2018.01.010","article-title":"Early caffeine and weaning from mechanical ventilation in preterm infants: a randomized, placebo-controlled trial","volume":"196","author":"Amaro","year":"2018","journal-title":"J Pediatr."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1002\/sctm.20-0330","article-title":"Stem cells for bronchopulmonary dysplasia in preterm infants: a randomized controlled phase II trial","volume":"10","author":"Ahn","year":"2021","journal-title":"Stem Cells Transl Med"},{"key":"B22","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.jpeds.2019.02.029","article-title":"Safety of intratracheal administration of human umbilical cord blood derived mesenchymal stromal cells in extremely low birth weight preterm infants","volume":"210","author":"Powell","year":"2019","journal-title":"J Pediatr"},{"key":"B23","unstructured":""},{"key":"B24","unstructured":""},{"key":"B25","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1111\/ped.14001","article-title":"Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia","volume":"61","author":"Namba","year":"2019","journal-title":"Pediatr Int"},{"key":"B26","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/j.jpeds.2004.03.026","article-title":"Rehospitalization in the first year of life among infants with bronchopulmonary dysplasia","volume":"144","author":"Smith","year":"2004","journal-title":"J Pediatr."},{"key":"B27","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jpeds.2017.05.029","article-title":"Evaluation and management of pulmonary hypertension in children with bronchopulmonary dysplasia","volume":"188","author":"Krishnan","year":"2017","journal-title":"J Pediatr"},{"key":"B28","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/j.clp.2015.08.010","article-title":"Pulmonary hypertension and vascular abnormalities in bronchopulmonary dysplasia","volume":"42","author":"Mourani","year":"2015","journal-title":"Clin Perinatol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1111\/ppe.12444","article-title":"Identification of gaps in the current knowledge on pulmonary hypertension in extremely preterm infants: a systematic review and meta-analysis","volume":"32","author":"Arjaans","year":"2018","journal-title":"Paediatr Perinat Epidemiol."}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2021.705033\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T09:01:47Z","timestamp":1629450107000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2021.705033\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,20]]},"references-count":29,"alternative-id":["10.3389\/fped.2021.705033"],"URL":"https:\/\/doi.org\/10.3389\/fped.2021.705033","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,20]]},"article-number":"705033"}}