{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T22:09:42Z","timestamp":1773180582302,"version":"3.50.1"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T00:00:00Z","timestamp":1664841600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Uterine leiomyomas are rare in the pediatric population with less than 20 cases in adolescences reported in the literature. Furthermore, these masses represent a common presentation of gynecologic tumors with increasing age. We report a case of a 14-year-old female who presented with abdominal pain and increasing abdominal girth. Workup with ultrasound, CT and MRI demonstrated a large pelvic mass. Complete resection by median laparotomy was performed. The mass weighed 5,596\u2005g and was 29.5\u2005cm\u2009\u00d7\u200927\u2005cm\u2009\u00d7\u200919\u2005cm; the pathological examination confirmed the hypothesis of leiomyoma. The patient remained asymptomatic at 3 months follow up.<\/jats:p>","DOI":"10.3389\/fped.2022.1020072","type":"journal-article","created":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T10:20:48Z","timestamp":1664878848000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Uterine leiomyoma in pediatric population: A case report and review of the literature"],"prefix":"10.3389","volume":"10","author":[{"given":"Cristina","family":"Martucci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Crocoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Persano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Bonito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Stracuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Alaggio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna","family":"Bertocchini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Accinni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Inserra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"591","DOI":"10.3109\/00016348109155494","article-title":"Uterine myoma in a 15-year-old girl","volume":"60","author":"Augensen","year":"1981","journal-title":"Acta Obstet Gynecol Scand"},{"key":"B2","first-page":"80","article-title":"Symptomatic fibroid uterus in a 15-year-old girl","volume":"89","author":"Bekker","year":"2004","journal-title":"Int Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1002\/1097-0142(196506)18:6%3C711::AID-CNCR2820180608%3E3.0.CO;2-4","article-title":"Smooth muscle tumors in children","volume":"18","author":"Botting","year":"1965","journal-title":"Cancer"},{"key":"B4","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.ejogrb.2015.11.023","article-title":"Cigarette smoking and risk of uterine myoma: systematic review and meta-analysis","volume":"197","author":"Chiaffarino","year":"","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0028-2243(86)90128-0","article-title":"A 15-year-old girl with an expansively growing tumour","volume":"22","author":"de Rooy","year":"1986","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S1083-3188(96)70030-X","article-title":"Uterine myomas in adolescents: case reports and a review of the literature","volume":"9","author":"Fields","year":"1996","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"B7","first-page":"294","article-title":"A giant uterine leiomyoma simulating an ovarian mass in a 16-year-old girl: a case report and review of the literature","volume":"27","author":"Grapsa","year":"2006","journal-title":"Eur J Gynaecol Oncol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1159\/000293043","article-title":"Uterine myoma causing uremia in a 15-year-old girl","volume":"32","author":"Heimer","year":"1991","journal-title":"Gynecol Obstet Invest"},{"key":"B9","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/j.1479-828X.1993.tb02398.x","article-title":"Cellular uterine myoma causing vaginal bleeding in a 15-year-old girl","volume":"33","author":"Morad","year":"1993","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1055\/s-2007-989299","article-title":"Uterine leiomyoma in a 14-year-old girl","volume":"18","author":"Diesen","year":"2008","journal-title":"Eur J Pediatr Surg"},{"key":"B11","first-page":"639","article-title":"Symptomatic myoma in a 13-year-old girl","volume":"105","author":"Wisot","year":"1969","journal-title":"Am J Obstet Gynecol"},{"key":"B12","first-page":"316","article-title":"Uterine myomas and smoking. 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