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Pediatr."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report values of the chest radiographic thoracic area (CRTA) in ventilated, term-born infants without respiratory disease and to evaluate whether CRTA is related to demographic data at birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective, observational cohort study in a tertiary neonatal unit at King's College Hospital NHS Foundation Trust, London, UK.<\/jats:p><jats:p>Newborn infants born after 36 completed weeks of gestation, ventilated for poor perinatal adaptation or hypoxic ischaemic encephalopathy without respiratory disease and admitted in a recent eight-year period (2014\u20132022).<\/jats:p><jats:p>The CRTA was assessed by free-hand tracing of the perimeter of the thoracic area as outlined by the diaphragm and the rib cage excluding the mediastinal structures and was calculated using the Sectra PACS software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and twenty-one infants (75 male) were included with a median (IQR) gestation of 40 (38\u201341) weeks and birth weight of 3.41 (3.04\u20133.75) kg. The median (IQR) CRTA was 2,589 (2,167\u20132,943) mm<jats:sup>2<\/jats:sup> and was significantly related to birth weight (<jats:italic>r<\/jats:italic>\u2009=\u20090.316, <jats:italic>p<\/jats:italic>\u2009=\u20090.003), gestation at birth (<jats:italic>r<\/jats:italic>\u2009=\u20090.193, <jats:italic>p<\/jats:italic>\u2009=\u20090.032) and birth weight <jats:italic>z<\/jats:italic>-score (<jats:italic>r<\/jats:italic>\u2009=\u20090.187, <jats:italic>p<\/jats:italic>\u2009=\u20090.038).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We report values of the chest radiographic thoracic area in ventilated term-born infants which could be used as reference for determining respiratory disease severity.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2022.1042341","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T13:18:41Z","timestamp":1673356721000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Brief research report: Chest radiographic thoracic area in term ventilated infants without respiratory disease"],"prefix":"10.3389","volume":"10","author":[{"given":"Theodore","family":"Dassios","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Adu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Greenough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1148\/radiol.2393050583","article-title":"Fetal lung volume measurements: determination with MR imaging\u2013effect of various factors","volume":"240","author":"Ward","year":"2006","journal-title":"Radiology"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1183\/09031936.00149213","article-title":"Can infant lung function predict respiratory morbidity during the first year of life in preterm infants?","volume":"43","author":"Proietti","year":"2014","journal-title":"Eur Respir J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1259\/bjr.72.856.10474492","article-title":"A radiographic method for assessing lung area in neonates","volume":"72","author":"Dimitriou","year":"1999","journal-title":"Br J Radiol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1259\/bjr.73.866.10884728","article-title":"Computer assisted analysis of the chest radiograph lung area and prediction of failure of extubation from mechanical ventilation in preterm neonates","volume":"73","author":"Dimitriou","year":"2000","journal-title":"Br J Radiol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"692210","DOI":"10.3389\/fped.2021.692210","article-title":"NeoAPACHE II. 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