{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:27:28Z","timestamp":1782973648866,"version":"3.54.5"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Enteral feeding after intestinal atresia has always been a concern for clinicians. But the present studies mainly focused on single factors. This research aimed to comprehensively analyze the multiple factors on complete enteral nutrition after primary anastomosis, and establish the convenient prediction model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively collected reliable information in neonates with intestinal atresia form January 2010 to June 2022. The cox regression analysis was performed to select independent risk factors and develop nomogram. Subsequently, ROC curve, calibration curve and decision curve were drawn to thoroughly evaluate the accuracy and applicability of the model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The predictors finally included in the model were gestational age, meconium peritonitis, distance from the anastomosis to the ileocecal region, diameter ratio of proximal to distal bowels, and time of initial feeding. The nomogram of predicting the probability of week 2, week 3 and week 4 was drawn and their area under the curve were 0.765, 0.785 and 0.747, respectively. Similarly, calibration and decision curve indicated that the prediction model had a great prediction performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical value of predictive models can be recognized. The hope is that the predictive model can help pediatricians reduce hospital costs and parental anxiety.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2022.1071056","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T06:14:45Z","timestamp":1670825685000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["The multivariate cox regression model for complete enteral nutrition after primary anastomosis in neonates with intestinal atresia"],"prefix":"10.3389","volume":"10","author":[{"given":"Yang","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le-dao","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai-hui","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-yong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-peng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,12,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.suc.2022.07.012","article-title":"Small bowel congenital anomalies: a review and update","volume":"102","author":"Morris","year":"2022","journal-title":"Surg Clin North Am"},{"key":"B2","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.rcl.2017.02.010","article-title":"Neonatal gastrointestinal emergencies: step-by-step approach","volume":"55","author":"Stanescu","year":"2017","journal-title":"Radiol Clin North Am"},{"key":"B3","doi-asserted-by":"publisher","first-page":"124","DOI":"10.3348\/kjr.2021.0111","article-title":"Gastrointestinal emergency in neonates and infants: a pictorial essay","volume":"23","author":"Choi","year":"2022","journal-title":"Korean J Radiol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1007\/s00383-018-4351-0","article-title":"A safe and efficacious preventive strategy in the high-risk surgical neonate: cycled total parenteral nutrition","volume":"34","author":"Sujka","year":"2018","journal-title":"Pediatr Surg Int"},{"key":"B5","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1186\/s12887-022-03629-z","article-title":"Diagnostic value of the microcolon using ultrasonography in small bowel atresia","volume":"22","author":"Ju","year":"2022","journal-title":"BMC Pediatr"},{"key":"B6","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.arcped.2018.02.005","article-title":"Committee on nutrition of the French society of pediatrics (CNSFP), and French society of neonatology (SFN). parenteral nutrition for preterm infants: issues and strategy","volume":"25","author":"Darmaun","year":"2018","journal-title":"Arch Pediatr"},{"key":"B7","doi-asserted-by":"publisher","first-page":"111572","DOI":"10.1016\/j.nut.2021.111572","article-title":"Enteral and parenteral energy intake and neurodevelopment in preterm infants: a systematic review","volume":"97","author":"De Nardo","year":"2022","journal-title":"Nutrition"},{"key":"B8","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.clp.2017.01.012","article-title":"Nutrition for the extremely preterm infant","volume":"44","author":"McNelis","year":"2017","journal-title":"Clin Perinatol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1159\/000381361","article-title":"Development of suck and swallow mechanisms in infants","volume":"66","author":"Lau","year":"2015","journal-title":"Ann Nutr Metab"},{"key":"B10","doi-asserted-by":"publisher","first-page":"151159","DOI":"10.1053\/j.semperi.2019.06.007","article-title":"Early enteral feeding in preterm infants","volume":"43","author":"Kwok","year":"2019","journal-title":"Semin Perinatol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1504","DOI":"10.1016\/j.jpedsurg.2021.10.006","article-title":"Meconium peritonitis: a 22-year review in a tertiary referral center","volume":"57","author":"Wong","year":"2022","journal-title":"J Pediatr Surg"},{"key":"B12","first-page":"411","article-title":"Ileostomy in extremely low birth weight and premature neonates","volume":"65","author":"Ferrara","year":"2013","journal-title":"Minerva Pediatr"},{"key":"B13","doi-asserted-by":"publisher","first-page":"e15208","DOI":"10.1111\/ped.15208","article-title":"Incidence of late severe intestinal complications after bowel atresia\/stenosis","volume":"64","author":"Hosokawa","year":"2022","journal-title":"Pediatr Int"},{"key":"B14","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1186\/s12887-022-03475-z","article-title":"The role of preserved bowel and mesentery fixation in apple-peel intestinal atresia","volume":"22","author":"Han","year":"2022","journal-title":"BMC Pediatr"},{"key":"B15","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1186\/s12887-022-03524-7","article-title":"Postoperative feeding in neonatal duodenal obstruction","volume":"22","author":"Aroonsaeng","year":"2022","journal-title":"BMC Pediatr"},{"key":"B16","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/j.earlhumdev.2014.09.017","article-title":"Malrotation and intestinal atresias","volume":"90","author":"Adams","year":"2014","journal-title":"Early Hum Dev"},{"key":"B17","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.anclin.2018.07.016","article-title":"Preoperative evaluation of the pediatric patient","volume":"36","author":"Basel","year":"2018","journal-title":"Anesthesiol Clin"},{"key":"B18","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1089\/lap.2021.0714","article-title":"Comparison of hand-sewn with stapled anastomosis in neonatal intestinal atresia surgery: a randomized controlled study","volume":"32","author":"Zheng","year":"2022","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"B19","doi-asserted-by":"publisher","first-page":"740","DOI":"10.29271\/jcpsp.2021.06.740","article-title":"Multiple small bowel atresia: resection or conservation?","volume":"30","author":"Govindarajan","year":"2021","journal-title":"J Coll Physicians Surg Pak"},{"key":"B20","doi-asserted-by":"publisher","first-page":"E5","DOI":"10.1016\/j.jpedsurg.2013.04.024","article-title":"Apple-peel intestinal atresia: enteroplasty for intestinal lengthening and primary anastomosis","volume":"48","author":"Onofre","year":"2013","journal-title":"J Pediatr Surg"}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2022.1071056\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T06:14:48Z","timestamp":1670825688000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2022.1071056\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,12]]},"references-count":20,"alternative-id":["10.3389\/fped.2022.1071056"],"URL":"https:\/\/doi.org\/10.3389\/fped.2022.1071056","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,12]]},"article-number":"1071056"}}