{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T22:45:53Z","timestamp":1771541153882,"version":"3.50.1"},"reference-count":14,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We evaluated the prevalence of preterm birth (PTB) and very low birth weight (VLBW) during Jan-Dec 2,020 (early COVID era) at 5 hospitals (2 in West Virginia, 3 in California) compared to Jan 2017\u2013Dec 2019 (pre-COVID) inclusive of 2 regional perinatal centers (1 in Huntington, WV and 1 in San Jose, CA) and 3 community hospitals (1 each in Cabell, Los Angeles and Santa Clara counties).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design\/methods<\/jats:title><jats:p>We examined PTB and VLBW rates of live births at 5 US hospitals from Jan 2017\u2013Dec 2020. We compared PTB and VLBW rates in 2020 to 2017\u20132019 using Poisson regression and rate ratio with a 95% confidence interval. We stratified live births by gestational age (GA) (&amp;lt;37, 33\u201336, and &amp;lt;33 weeks) and birth weight (\u22641,500\u2005g, &amp;gt;1,001\u2005g to \u22641,500\u2005g, \u22641,000\u2005g). We examined PTB rates at 4 of the hospitals during Jan-Dec 2020 and compared them to the prior period of Jan 2017\u2013Dec 2019 using Statistical Process Control (SPC) for quarterly data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We examined PTB and VLBW rates in 34,599 consecutive live births born Jan 2017\u2013Dec 2019 to rates of 9,691 consecutive live births in 2020. There was no significant change in PTB (&amp;lt;37 weeks GA) rate, 10.6% in 2017\u20132019 vs. 11.0% in 2020 (<jats:italic>p<\/jats:italic>\u2009=\u20090.222). Additionally, there was no significant change when comparing VLBW rates in 2017\u20132019 to 2020, 1.4% in 2017\u20132019 vs. 1.5% in 2020 (<jats:italic>p<\/jats:italic>\u2009=\u20090.832).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found no significant change in the rates of PTB or VLBW when combining the live birth data of 5 US hospitals in 3 different counties.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2022.1093371","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T14:48:35Z","timestamp":1673362115000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Are preterm birth and very low birth weight rates altered in the early COVID (2020) SARS-CoV-2 era?"],"prefix":"10.3389","volume":"10","author":[{"given":"Kayla","family":"Rodriguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew 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Rani","family":"Narasimhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Machelnil","family":"Cormier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Beth","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupalee","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balaji","family":"Govindaswami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2020-003075","article-title":"Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a \u2018natural experiment\u2019 allowing analysis of data from the prior two decades","volume":"5","author":"Philip","year":"2020","journal-title":"BMJ Glob Health"},{"key":"B2","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1136\/archdischild-2020-319990","article-title":"Danish premature birth rates during the COVID-19 lockdown","volume":"106","author":"Hedermann","year":"2021","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e006359","DOI":"10.1136\/bmjgh-2021-006359","article-title":"Are COVID-19 mitigation measures reducing preterm birth rate in China?","volume":"6","author":"Bian","year":"2021","journal-title":"BMJ Glob Health"},{"key":"B4","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1001\/jama.2020.20991","article-title":"Changes in preterm birth phenotypes and stillbirth at 2 Philadelphia hospitals during the SARS-CoV-2 pandemic, march-June 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