{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:14:26Z","timestamp":1784042066426,"version":"3.55.0"},"reference-count":72,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The association between preterm birth and neurodevelopmental delays have been well examined, however, reliable estimates for the full range of gestational age (GA) are limited, and few studies explored the impact of post-term birth on child development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to examine the long-term neuropsychological outcomes of children born in a full range of GA with a national representative sample in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective population-based cohort study, a total of 137,530 preschoolers aged 3\u20135 years old (65,295\/47.5% females and 72,235\/52.5% males) were included in the final analysis. The Ages and Stages Questionnaires-Third Edition (ASQ-3) was completed by parents to evaluate children's neurodevelopment. The associations between GA and neurodevelopment were analyzed by a generalized additive mixed model with thin plate regression splines. Logistic regression was also conducted to examine the differences in children's development with different GAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a non-linear relationship between GA and children's neurodevelopmental outcomes with the highest scores at 40 weeks gestational age. The adjusted risks of GAs (very and moderately preterm, late-preterm, early-term, and post-term groups) on suspected developmental delays were observed in communication (OR were 1.83, 1.28, 1.13, and 1.21 respectively, each <jats:italic>p<\/jats:italic> &amp;lt; 0.05), gross motor skill (OR were 1.67, 1.38, 1.10, and 1.05 respectively, each <jats:italic>p<\/jats:italic> &amp;lt; 0.05), and personal social behavior (OR were 1.01, 1.36, 1.12, and 1.18 respectively, each <jats:italic>p<\/jats:italic> &amp;lt; 0.05). The adjusted OR of very and moderately preterm, late-preterm, and early-term were observed in fine motor skills (OR were 1.53, 1.22, and 1.09 respectively, each <jats:italic>p<\/jats:italic> &amp;lt; 0.05) and problem-solving (OR were 1.33, 1.12, and 1.06 respectively, each <jats:italic>p<\/jats:italic> &amp;lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>GAs is a risk factor for neurodevelopmental delays in preschoolers after controlling for a wide range of covariates, and 40\u201341 weeks may be the ideal delivery GA for optimal neurodevelopmental outcomes. Close observation and monitoring should be considered for early- and post-term born children as well as pre-term children.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2022.860192","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T07:33:35Z","timestamp":1653982415000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Association of Gestational Age at Birth With Subsequent Neurodevelopment in Early Childhood: A National Retrospective Cohort Study in China"],"prefix":"10.3389","volume":"10","author":[{"given":"Jing","family":"Hua","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna L.","family":"Barnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanjie","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gareth J.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxuan","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenchong","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"B1","unstructured":"ICD-11 for Mortality and Morbidity Statistics2020"},{"key":"B2","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2013"},{"key":"B3","author":"Melillo","year":"2004","journal-title":"Neurobehavioral Disorders of Childhood: An Evolutionary Perspective."},{"key":"B4","author":"Accardo","year":"2008","journal-title":"Capute & Accardo's Neurodevelopmental Disabilities in Infancy and Childhood"},{"key":"B5","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.21037\/tp.2020.02.03","article-title":"Neurodevelopmental and neurobehavioral disorders","volume":"9","author":"Patel","year":"2020","journal-title":"Transl Pediatr."},{"key":"B6","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/jp.2015.28","article-title":"ADHD and developmental speech\/language disorders in late preterm, early term and term infants","volume":"35","author":"Rabie","year":"2015","journal-title":"J Perinatol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1542\/peds.2016-1848","article-title":"Breastfeeding, cognitive and noncognitive development in early childhood: a population study","author":"Girard","year":"2017","journal-title":"Pediatrics"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e1003207","DOI":"10.1371\/journal.pmed.1003207","article-title":"Gestational age and the risk of autism spectrum disorder in Sweden, Finland, and Norway: a cohort study","volume":"17","author":"Persson","year":"2020","journal-title":"PLoS Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"489e481","DOI":"10.1016\/j.ajog.2012.03.024","article-title":"Placental pathology and long-term neurodevelopment of very preterm infants","volume":"206","author":"van Vliet","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1542\/peds.2010-2257","article-title":"Early childhood development of late-preterm infants: a systematic review","volume":"127","author":"McGowan","year":"2011","journal-title":"Pediatrics."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1542\/peds.2010-1536","article-title":"Late-preterm birth and its association with cognitive and socioemotional outcomes at 6 years of age","volume":"126","author":"Talge","year":"2010","journal-title":"Pediatrics."},{"key":"B12","doi-asserted-by":"publisher","first-page":"e622","DOI":"10.1542\/peds.2009-3598","article-title":"Late preterm infants have worse 24-month neurodevelopmental outcomes than term infants","volume":"127","author":"Woythaler","year":"2011","journal-title":"Pediatrics."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e896","DOI":"10.1136\/bmj.e896","article-title":"Effects of gestational age at birth on health outcomes at 3 and 5 years of age: population based cohort study","volume":"344","author":"Boyle","year":"2012","journal-title":"BMJ."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e025275","DOI":"10.1136\/bmjopen-2018-025275","article-title":"Differentiating the cognitive development of early-term births in infants and toddlers: a cross-sectional study in China","volume":"9","author":"Hua","year":"2019","journal-title":"BMJ Open."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1097\/01.AOG.0000437385.88715.4a","article-title":"ACOG Committee Opinion No 579: definition of term pregnancy","volume":"122","year":"2013","journal-title":"Obstetr Gynecol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1007\/s12519-015-0049-8","article-title":"Early term infants are at increased risk of requiring neonatal intensive care","volume":"12","author":"Mally","year":"2016","journal-title":"World J Pediatr."},{"key":"B17","doi-asserted-by":"publisher","first-page":"e1475","DOI":"10.1542\/peds.2012-3215","article-title":"Developmental scores at 1 year with increasing gestational age, 37-41 weeks","volume":"131","author":"Rose","year":"2013","journal-title":"Pediatrics."},{"key":"B18","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1542\/peds.2004-1169","article-title":"Late gestation cerebellar growth is rapid and impeded by premature birth","volume":"115","author":"Limperopoulos","year":"2005","journal-title":"Pediatrics."},{"key":"B19","doi-asserted-by":"publisher","first-page":"e113758","DOI":"10.1371\/journal.pone.0113758","article-title":"Longer gestation among children born full term influences cognitive and motor development","volume":"9","author":"Espel","year":"2014","journal-title":"PLoS ONE."},{"key":"B20","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1093\/aje\/kwp413","article-title":"Variation in child cognitive ability by week of gestation among healthy term births","volume":"171","author":"Yang","year":"2010","journal-title":"Am J Epidemiol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1542\/peds.2011-2157","article-title":"Academic achievement varies with gestational age among children born at term","volume":"130","author":"Noble","year":"2012","journal-title":"Pediatrics."},{"key":"B22","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1093\/ije\/dyw284","article-title":"Gestational age at birth and academic performance: population-based cohort study","volume":"46","author":"Abel","year":"2017","journal-title":"Int J Epidemiol"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1093\/ije\/dyq070","article-title":"Gestational age differences in health and development among young Swedish men born at term","volume":"39","author":"Yang","year":"2010","journal-title":"Int J Epidemiol."},{"key":"B24","first-page":"160","article-title":"Common questions about late-term and postterm pregnancy","volume":"90","author":"Wang","year":"2014","journal-title":"Am Fam Physician."},{"key":"B25","doi-asserted-by":"crossref","first-page":"e257","DOI":"10.1542\/peds.2011-2157","article-title":"Academic achievement varies with gestational age among children born at term","volume":"130","author":"Noble","year":"2012","journal-title":"Pediatrics."},{"key":"B26","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/aje\/kwp413","article-title":"Variation in child cognitive ability by week of gestation among healthy term births","volume":"171","author":"Yang","year":"2010","journal-title":"Am J Epidemiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/jp.2011.43","article-title":"Perinatal morbidity and mortality in late-term and post-term pregnancy: NEOSANE perinatal network's experience in Mexico","volume":"31","author":"De Los Santos-Garate AM","year":"2011","journal-title":"J Perinatol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.ajog.2008.05.015","article-title":"Increased neonatal mortality among normal-weight births beyond 41 weeks of gestation in California","volume":"199","author":"Bruckner","year":"2008","journal-title":"Am J Obstet Gynecol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1080\/14767058.2018.1514379","article-title":"Investigating the association between post-term birth and long term cognitive, developmental and educational impacts: a systematic review and Meta-analysis","volume":"33","author":"Glover Williams","year":"2020","journal-title":"J Matern Fetal Neonatal Med."},{"key":"B30","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1093\/ije\/dys043","article-title":"Post-term birth and the risk of behavioural and emotional problems in early childhood","volume":"41","author":"El Marroun","year":"2012","journal-title":"Int J Epidemiol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"2431","DOI":"10.1007\/s10803-012-1501-4","article-title":"The effect of gestational age on symptom severity in children with autism spectrum disorder","volume":"42","author":"Movsas","year":"2012","journal-title":"J Autism Dev Disord."},{"key":"B32","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1001\/jamapediatrics.2018.1315","article-title":"Association of gestational age at birth with symptoms of attention-deficit\/hyperactivity disorder in children","volume":"172","author":"Ask","year":"2018","journal-title":"JAMA Pediatr."},{"key":"B33","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1371\/journal.pone.0198482","article-title":"Low gestational age at birth and difficulties in school-A matter of 'dose'","author":"Wiingreen","year":"2018","journal-title":"PLoS ONE"},{"key":"B34","doi-asserted-by":"publisher","first-page":"e0221675","DOI":"10.1371\/journal.pone.0221675","article-title":"Concurrent validity of the ages and stages questionnaire and the bayley scales of infant development III in China","volume":"14","author":"Yue","year":"2019","journal-title":"PLoS ONE."},{"key":"B35","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.earlhumdev.2015.01.008","article-title":"Parental and professional assessment of early child development: the ASQ-3 and the Bayley-III-NL","volume":"91","author":"Steenis","year":"2015","journal-title":"Early Hum Dev."},{"key":"B36","first-page":"913","article-title":"Zhonghua er ke za zhi =","volume":"53","author":"Wei","year":"2015","journal-title":"Chin J Pediatr."},{"key":"B37","doi-asserted-by":"publisher","first-page":"e0160962","DOI":"10.1371\/journal.pone.0160962","article-title":"Concurrent validity and feasibility of short tests currently used to measure early childhood development in large scale studies","volume":"11","author":"Rubio-Codina","year":"2016","journal-title":"PLoS ONE."},{"key":"B38","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1016\/j.apmr.2016.11.001","article-title":"Brief review of psychometric properties and clinical utility of the ages and stages questionnaires, third edition for evaluating pediatric development","volume":"98","author":"Rothstein","year":"2017","journal-title":"Arch Phys Med Rehabil."},{"key":"B39","author":"Squires","year":"2009","journal-title":"Psychometric Studies of ASQ"},{"key":"B40","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0140-6736(03)15268-3","article-title":"Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies","volume":"363","year":"2004","journal-title":"Lancet."},{"key":"B41","doi-asserted-by":"publisher","first-page":"824","DOI":"10.21037\/apm.2020.04.27","article-title":"The changing situation about maternal age, risk factors and pregnancy outcomes after the two-child policy: a retrospective cohort study","volume":"9","author":"Teng","year":"2020","journal-title":"Ann Palliat Med."},{"key":"B42","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1371\/journal.pmed.1000289","article-title":"Gestational age at delivery and special educational need: retrospective cohort study of 407,503 Schoolchildren","author":"MacKay","year":"2010","journal-title":"PLoS Med"},{"key":"B43","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.ajog.2011.10.068","article-title":"Autism risk in small- and large-for-gestational-age infants","author":"Moore","year":"2012","journal-title":"Am J Obstetr Gynecol"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1056\/NEJM199206113262402","article-title":"Induction of labor as compared with serial antenatal monitoring in postterm pregnancy - a randomized controlled trial","volume":"326","author":"Hannah","year":"1992","journal-title":"New Engl J Med."},{"key":"B45","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1136\/bmjopen-2012-001152","article-title":"Cause-specific infant mortality in a population-based Swedish study of term and post-term births: the contribution of gestational age and birth weight","author":"Altman","year":"2012","journal-title":"BMJ Open"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1001\/jama.2011.1331","article-title":"Gestational age at birth and mortality in young adulthood","volume":"306","author":"Crump","year":"2011","journal-title":"JAMA."},{"key":"B47","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1007\/s10198-016-0850-x","article-title":"Cost effects of preterm birth: a comparison of health care costs associated with early preterm, late preterm, and full-term birth in the first 3 years after birth","volume":"18","author":"Jacob","year":"2017","journal-title":"Eur J Health Econ."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fpsyg.2011.00001","article-title":"Children's brain development benefits from longer gestation","volume":"2","author":"Davis","year":"2011","journal-title":"Front Psychol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.neuroimage.2014.06.048","article-title":"Longer gestation is associated with more efficient brain networks in preadolescent children","volume":"100","author":"Kim","year":"2014","journal-title":"Neuroimage."},{"key":"B50","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1203\/00006450-199810000-00019","article-title":"Microstructural development of human newborn cerebral white matter assessed in vivo by diffusion tensor magnetic resonance imaging","volume":"44","author":"H\u00fcppi","year":"1998","journal-title":"Pediatr Res."},{"key":"B51","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/j.clp.2006.09.004","article-title":"Neurodevelopmental outcome of the late preterm infant","volume":"33","author":"Adams-Chapman","year":"2006","journal-title":"Clin Perinatol"},{"key":"B52","doi-asserted-by":"publisher","first-page":"13135","DOI":"10.1073\/pnas.1001229107","article-title":"Similar patterns of cortical expansion during human development and evolution","volume":"107","author":"Hill","year":"2010","journal-title":"Proc Natl Acad Sci U S A."},{"key":"B53","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1001\/jama.288.6.728","article-title":"Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysis","volume":"288","author":"Bhutta","year":"","journal-title":"JAMA."},{"key":"B54","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1001\/jama.284.15.1939","article-title":"Regional brain volume abnormalities and long-term cognitive outcome in preterm infants","volume":"284","author":"Peterson","year":"2000","journal-title":"JAMA."},{"key":"B55","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.neuroimage.2013.10.034","article-title":"Identification and interpretation of microstructural abnormalities in motor pathways in adolescents born preterm","volume":"87","author":"Groeschel","year":"2014","journal-title":"Neuroimage."},{"key":"B56","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1093\/brain\/awm282","article-title":"Grey and white matter distribution in very preterm adolescents mediates neurodevelopmental outcome","volume":"131","author":"Nosarti","year":"2008","journal-title":"Brain."},{"key":"B57","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.neuroimage.2013.11.048","article-title":"Preterm birth affects the developmental synergy between cortical folding and cortical connectivity observed on multimodal MRI","volume":"89","author":"Melbourne","year":"2014","journal-title":"Neuroimage."},{"key":"B58","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/S1474-4422(08)70294-1","article-title":"Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances","volume":"8","author":"Volpe","year":"2009","journal-title":"Lancet Neurol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1093\/cercor\/bhr176","article-title":"The effect of preterm birth on thalamic and cortical development","volume":"22","author":"Ball","year":"2012","journal-title":"Cereb Cortex."},{"key":"B60","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s11689-018-9253-x","article-title":"Aberrant structural and functional connectivity and neurodevelopmental impairment in preterm children","volume":"10","author":"Rogers","year":"2018","journal-title":"J Neurodev Disord."},{"key":"B61","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1586\/eem.12.33","article-title":"Neurobehavioral risk is associated with gestational exposure to stress hormones","volume":"7","author":"Sandman","year":"2012","journal-title":"Expert Rev Endocrinol Metab."},{"key":"B62","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.ejpn.2018.02.013","article-title":"Neurological outcome at 6 and 12 months corrected age in hospitalised late preterm infants -a prospective study","volume":"22","author":"Chatziioannidis","year":"2018","journal-title":"Eur J Paediatric Neurol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1093\/ije\/dyv329","article-title":"Preterm delivery and risk for early language delays: a sibling-control cohort study","volume":"45","author":"Zambrana","year":"2016","journal-title":"Int J Epidemiol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1016\/j.jpeds.2014.08.027","article-title":"Communication impairments in early term and late preterm children: a prospective cohort study following children to age 36 months","volume":"165","author":"Stene-Larsen","year":"2014","journal-title":"J Pediatr."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1111\/aogs.13644","article-title":"Long-term cognition and behavior in children born at early term gestation: a systematic review","volume":"98","author":"Nielsen","year":"2019","journal-title":"Acta Obstet Gynecol Scand."},{"key":"B66","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1001\/jamapediatrics.2018.1394","article-title":"Developmental Coordination Disorder and Its Association With Developmental Comorbidities at 6.5 Years in Apparently Healthy Children Born Extremely Preterm","volume":"172","author":"Bolk","year":"2018","journal-title":"JAMA Pediatr."},{"key":"B67","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1053\/j.semperi.2006.02.006","article-title":"The near-term (late preterm) human brain and risk for periventricular leukomalacia: a review","volume":"30","author":"Kinney","year":"2006","journal-title":"Semin Perinatol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"e265","DOI":"10.1371\/journal.pmed.0030265","article-title":"Abnormal cortical development after premature birth shown by altered allometric scaling of brain growth","volume":"3","author":"Kapellou","year":"2006","journal-title":"PLoS Med."},{"key":"B69","doi-asserted-by":"publisher","first-page":"199","DOI":"10.33549\/physiolres.934198","article-title":"Impact of perinatal hypoxia on the developing brain","volume":"69","author":"Piesova","year":"2020","journal-title":"Physiol Res."},{"key":"B70","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1093\/oxfordjournals.aje.a112641","article-title":"Causes of perinatal mortality excess in prolonged gestations","volume":"108","author":"Naeye","year":"1978","journal-title":"Am J Epidemiol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"912","DOI":"10.2741\/2113","article-title":"Corticotrophin releasing hormone and the timing of birth","volume":"12","author":"Smith","year":"2007","journal-title":"Front Biosci."},{"key":"B72","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/S0303-7207(01)00624-4","article-title":"The fetal placental hypothalamic\u2013pituitary\u2013adrenal (HPA) axis, parturition and post natal health","volume":"185","author":"Challis","year":"2001","journal-title":"Molec Cell Endocrinol."}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2022.860192\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T07:33:47Z","timestamp":1653982427000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2022.860192\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,31]]},"references-count":72,"alternative-id":["10.3389\/fped.2022.860192"],"URL":"https:\/\/doi.org\/10.3389\/fped.2022.860192","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,31]]},"article-number":"860192"}}