{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:24:29Z","timestamp":1787027069746,"version":"build-2736575974"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T00:00:00Z","timestamp":1652918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Improved survival in extremely low birth weight infants (ELBWI) in Sub-Saharan Africa has raised the question whether these survivors have an increased chance of adverse neurodevelopmental outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe neurodevelopmental outcomes of ELBWI in a neonatal unit in South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a prospective follow-up study. All ELBWI who survived to discharge between 1 July 2013 and 31 December 2017 were invited to attend the clinic. Bayley Scales of Infant and Toddler Development (version III) were conducted at 9 to 12 months and 18 to 24 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 723 ELBWI admissions during the study period, 292 (40.4%) survived to hospital discharge and 85\/292 (29.1%) attended the neonatal follow up clinic. The mean birth weight was 857.7 g (95% CI: 838.2\u2013877.2) and the mean gestational age was 27.5 weeks (95% CI 27.1\u201327.9). None of the infants had any major complication of prematurity. A total of 76\/85 (89.4%) of the infants had a Bayley-III assessment at a mean corrected age of 17.21 months (95% CI: 16.2\u201318.3). The mean composite scores for cognition were 98.4 (95% CI 95.1\u2013101.7), language 89.9 (95% CI 87.3\u201392.5) and motor 97.6 (95% CI 94.5\u2013100.6). All mean scores fell within the normal range, The study found 28 (36.8%) infants to be \u201c\n                      <jats:italic>at risk<\/jats:italic>\n                      \u201d for neurodevelopmental delay.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study demonstrates good neurodevelopmental outcome in a small group of surviving ELBWI, but these results must be interpreted in the context of the high mortality in this group of infants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fped.2022.902263","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T01:48:35Z","timestamp":1652924915000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Neurodevelopmental Outcomes of Extremely Low Birth Weight Survivors in Johannesburg, South 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