{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T04:50:34Z","timestamp":1780548634382,"version":"3.54.1"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>In children, the manifestations of coronavirus disease 2019 (COVID-19) in the acute phase are considered mild compared with those in adults; however, some children experience a severe disease that requires hospitalization. This study was designed to present the operation and follow-up results of the Post-COVID-19 Detection and Monitoring Sequels Clinic of Hospital Infantil de Mexico Federico G\u00f3mez in managing children with a history of SARS-CoV-2 infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective study conducted from July 2020 to December 2021, which included 215 children aged 0\u201318 years who tested positive for SARS-CoV-2 on polymerase chain reaction and\/or immunoglobulin G test. The follow-up was conducted in the pulmonology medical consultation; ambulatory and hospitalized patients were assessed at 2, 4, 6, and 12 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of the patients was 9.02 years, and neurological, endocrinological, pulmonary, oncological, and cardiological comorbidities were the most commonly observed among the patients. Moreover, 32.6% of the children had persistent symptoms at 2 months, 9.3% at 4 months, and 2.3% at 6 months, including dyspnea, dry cough, fatigue, and runny nose; the main acute complications were severe pneumonia, coagulopathy, nosocomial infections, acute renal injury, cardiac dysfunction, and pulmonary fibrosis. The more representative sequelae were alopecia, radiculopathy, perniosis, psoriasis, anxiety, and depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study showed that children experience persistent symptoms, such as dyspnea, dry cough, fatigue, and runny nose, although to a lesser extent than adults, with significant clinical improvement 6 months after the acute infection. These results indicate the importance of monitoring children with COVID-19 through face-to-face consultations or telemedicine, with the objective of offering multidisciplinary and individualized care to preserve the health and quality of life of these children.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2023.1016394","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T07:38:17Z","timestamp":1675064297000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Long COVID in children and adolescents: COVID-19 follow-up results in third-level pediatric hospital"],"prefix":"10.3389","volume":"11","author":[{"given":"Lourdes Mar\u00eda del Carmen","family":"Jamaica Balderas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amairani","family":"Navarro Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana Azeneth","family":"Dragustinovis Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Isabel","family":"Orellana Jerves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter Ernesto","family":"Sol\u00eds Figueroa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange Gabriela","family":"Koretzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horacio","family":"M\u00e1rquez Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Kl\u00fcnder Kl\u00fcnder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Gardu\u00f1o","family":"Espinosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Nieto Zerme\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Villa Guill\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3mulo Erick","family":"Rosales Uribe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Olivar L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/life12020285","article-title":"Long COVID in children and adolescents","volume":"12","author":"Fainardi","year":"2022","journal-title":"Life"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1007\/s00431-021-04345-z","article-title":"Long COVID symptoms and duration in SARS-CoV-2 positive children \u2014 a nationwide cohort study","volume":"181","author":"Borch","year":"2022","journal-title":"Eur J Pediatr"},{"key":"B3","author":"Luis","year":""},{"key":"B4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0243882","article-title":"Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection","volume":"12","author":"Id","year":"2020","journal-title":"PloS One"},{"key":"B5","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.1093\/eurheartj\/suab080","article-title":"Long COVID: long-term effects?","volume":"23","author":"Di Toro","year":"2021","journal-title":"Eur Hear J"},{"key":"B6","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.1002\/ppul.25521","article-title":"Pediatric long-COVID: an overlooked phenomenon?","volume":"56","author":"Brackel","year":"2021","journal-title":"Pediatr Pulmonol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/bmj.n1648","article-title":"Long COVID - 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