{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:15:01Z","timestamp":1753892101883,"version":"3.41.2"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T00:00:00Z","timestamp":1678924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Subacute presentation with gait preservation is rare in the initial presentation of transverse myelitis (TM) in children. Lyme TM is poorly described in the literature. Here, we present the case of a 10-year-old boy who presented with neck pain with irradiation in the upper limbs for 13 days, accompanied by a right latero-torticollis. Magnetic resonance imaging (MRI) of the spine showed a hypersignal in the centromedullary T2 weighted image (WI) between C1 and C7, which was suggestive of cervical TM. A lumbar puncture revealed pleocytosis and proteinorachia. The test results of<jats:italic>Borrelia<\/jats:italic>IgG in the blood and intrathecal IgG synthesis were positive, confirming the diagnosis of TM secondary to Lyme disease. The patient was treated with high doses of steroids and antibiotics, following which he recovered completely. After a review of the clinical features of the eight previously published pediatric cases, we can conclude that Lyme TM usually has a subacute clinical presentation and is frequently limited to the cervical spine with pure sensory symptoms and gait preservation. Moreover, acute and chronic sphincter dysfunction is rare, and recovery is usually complete.<\/jats:p>","DOI":"10.3389\/fped.2023.1064234","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T06:49:25Z","timestamp":1678949365000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: Subacute transverse myelitis with gait preservation secondary to Lyme disease and a review of the literature"],"prefix":"10.3389","volume":"11","author":[{"given":"Charlotte","family":"Colot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Adler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9line","family":"Mignon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"De Leucio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice","family":"Jissendi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Fonteyne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alec","family":"Aeby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1212\/WNL.0000000000002820","article-title":"Pediatric transverse myelitis","volume":"87","author":"Absoud","year":"2016","journal-title":"Neurology"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.1212\/01.wnl.0000260609.11357.6f","article-title":"Acute transverse myelitis in childhood center-based analysis of 47 cases","volume":"68","author":"Pidcock","year":"2007","journal-title":"Neurology"},{"key":"B3","first-page":"417","article-title":"Livre \u201cNeurologie p\u00e9diatrique\u201d 3\u00e8me \u00e9dition M\u00e9decine-Sciences","volume":"1","author":"Hugonenq","year":"2010","journal-title":"Flammarion"},{"key":"B4","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.pediatrneurol.2012.12.001","article-title":"Acute transverse myelitis in a child with lyme disease and a review of literature","volume":"48","author":"Erol","year":"2013","journal-title":"Pediatr Neurol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1159\/000438696","article-title":"Pediatric acute longitudinal extensive transverse myelitis secondary to neuroborreliosis","volume":"7","author":"Khan","year":"2015","journal-title":"Case Rep Neurol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.arcped.2013.03.025","article-title":"My\u00e9lite transverse aigu\u00eb et maladie de lyme: \u00e0 propos d\u2019un cas","volume":"20","author":"Gaudichon","year":"2013","journal-title":"Arch Pediatr"},{"key":"B7","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1742-1241.1997.tb11541.x","article-title":"Subacute cerebellitis in lyme disease","volume":"51","author":"Neophytides","year":"1997","journal-title":"Int J Clin Pract"},{"key":"B8","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1038\/nrmicro2714","article-title":"Of ticks, mice and men: understanding the dual-host lifestyle of lyme disease spirochaetes","volume":"10","author":"Radolf","year":"2012","journal-title":"Nat Rev Microbiol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1007\/s15010-010-0028-x","article-title":"Acute transverse myelitis in lyme neuroborreliosis","volume":"38","author":"Bigi","year":"2010","journal-title":"Infection"},{"key":"B10","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.ejpn.2009.08.003","article-title":"Uncommon manifestations of neuroborreliosis in children","volume":"14","author":"Baumann","year":"2010","journal-title":"Eur J Paediatr Neurol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1159\/000081864","article-title":"Acute transverse myelitis as a main manifestation of early stage II neuroborreliosis in two patients","volume":"52","author":"Meurs","year":"2004","journal-title":"Eur Neurol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1097\/00004728-199901000-00009","article-title":"Unusual presentations of neuroborreliosis (lyme disease) in childhood","volume":"23","author":"Huisman","year":"1999","journal-title":"J Comput Assist Tomogr"},{"key":"B13","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1055\/s-2008-1071427","article-title":"Infective acute transverse myelopathy. 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