{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:45:57Z","timestamp":1789425957463,"version":"build-2803163510"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess whether decreased regional cerebral oxygen saturation (rScO<jats:sub>2<\/jats:sub>) is associated with the emergence delirium (ED) following general anesthesia in the pediatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective observational cohort study was conducted on 113 children (ASA I\u2013III) aged 2\u201314 years who underwent selective surgery under general anesthesia between 2022-01 and 2022-04. Intraoperatively, the rScO<jats:sub>2<\/jats:sub> was monitored using a cerebral oximeter. The Pediatric Anesthesia Emergence Delirium (PAED) score was used to evaluate the patients for ED.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of ED was 31%. Low rScO<jats:sub>2<\/jats:sub> was reported in 41.6% of patients, who had a higher incidence of ED (<jats:italic>P<\/jats:italic>\u2009&amp;lt;\u20090.001) than those who did not experience desaturation. Logistic regression analysis revealed that decreased rScO<jats:sub>2<\/jats:sub> was significantly associated with incident ED events [odds ratio (OR), 10.77; 95% confidence interval, 3.31\u201335.05]. Children under 3 years of age had a higher incidence of ED after rScO<jats:sub>2<\/jats:sub> desaturation during anesthesia compared to older children (OR, 14.17 vs. 4.64).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intraoperative rScO<jats:sub>2<\/jats:sub> desaturation significantly increased the incidence of ED following general anesthesia. Monitoring should be enhanced to improve the oxygen balance in vital organs to improve the quality and safety of anesthesia.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2023.1117455","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T09:32:20Z","timestamp":1686216740000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Reduced regional cerebral oxygen saturation increases risk for emergence delirium in pediatric 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