{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:14:45Z","timestamp":1777630485486,"version":"3.51.4"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T00:00:00Z","timestamp":1687478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>To observe the postoperative recovery following ureteral dilation in primary obstructive megaureter (POM) after ureteral implantation, and evaluate the risk factors affecting ureter diameter resolution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A retrospective study was performed in patients with POM who underwent ureteral reimplantation using the Cohen procedure. Patient characteristics, perioperative parameters, and postoperative outcomes were also analysed. A widest ureteral diameter of &amp;lt;7\u2005mm was defined as a normal shape and outcome. Survival time was defined as the time from surgery to ureteral dilation recovery or to the last follow-up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 49 patients (54 ureters) were included in the analysis. The survival time ranged from 1 to 53 months. The shapes of a total of 47 (87.04%) megaureters recovered, and most (29\/47) resolutions happened within 6 months after surgery. In the univariate analysis, bilateral ureterovesical reimplantation (<jats:italic>p\u2009<\/jats:italic>=\u20090.015), ureteral terminal tapering (<jats:italic>p\u2009<\/jats:italic>=\u20090.019), weight (<jats:italic>p\u2009<\/jats:italic>=\u20090.036), and age (<jats:italic>p\u2009<\/jats:italic>=\u20090.015) were associated with the recovery time of ureteral dilation. A delayed recovery of ureteral diameter was noted in bilateral reimplantation (HR\u2009=\u20090.336, <jats:italic>p\u2009<\/jats:italic>=\u20090.017) using multivariate Cox regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ureteral dilation in POM mostly returned to normal within six postoperative months. Moreover, bilateral ureterovesical reimplantation is a risk factor for delayed postoperative recovery of ureter dilation in POM.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2023.1164474","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T16:16:20Z","timestamp":1687623380000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter"],"prefix":"10.3389","volume":"11","author":[{"given":"Yan","family":"He","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingrui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoquan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoqiang","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangyu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongde","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,6,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1046\/j.1464-410x.2000.00922.x","article-title":"Primary megaureter: current trends in diagnosis and treatment","volume":"86","author":"Shokeir","year":"2000","journal-title":"BJU Int"},{"key":"B2","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/j.jpedsurg.2012.11.017","article-title":"Resolution of primary non-refluxing megaureter: an observational study","volume":"48","author":"Ranawaka","year":"2013","journal-title":"J Pediatr Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jpurol.2013.09.018","article-title":"British association of paediatric urologists consensus statement on the management of the primary obstructive megaureter","volume":"10","author":"Farrugia","year":"2014","journal-title":"J Pediatr Urol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s00240-017-1005-y","article-title":"Functional and morphological recovery of solitary kidneys after drainage. Double J stent placement vs emergency ureteroscopy: which one is reasonable?","volume":"46","author":"Sarica","year":"2018","journal-title":"Urolithiasis"},{"key":"B5","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.urology.2016.02.045","article-title":"Outcomes of pyeloplasty in very poorly functioning kidneys: examining the myths","volume":"92","author":"Nayyar","year":"2016","journal-title":"Urology"},{"key":"B6","doi-asserted-by":"publisher","first-page":"431","DOI":"10.3760\/cma.j.issn.1000-6702.2016.06.009","article-title":"Functional and morphological outcome after pyeloplasty for children with unilateral hydronephrosis","volume":"37","author":"Li","year":"2016","journal-title":"Chinese Journal of Urology"},{"key":"B7","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1089\/end.2005.19.295","article-title":"Endoscopic cross-trigonal ureteral reimplantation under carbon dioxide bladder insufflation: a novel technique","volume":"19","author":"Yeung","year":"2005","journal-title":"J Endourol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1016\/j.juro.2013.03.008","article-title":"Long-Term followup of primary nonrefluxing megaureter","volume":"190","author":"Di Renzo","year":"2013","journal-title":"J Urol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"404","DOI":"10.3969\/j.issn.1674-3865.2017.05.012","article-title":"Study on postoperative recovery of renal morphology and function in children with hydronephrosis caused by stenosis of ureteropelvic junction","volume":"9","author":"Peng","year":"2017","journal-title":"Chin Pediatr Integr Tradit West Med"},{"key":"B10","doi-asserted-by":"publisher","first-page":"102.e1","DOI":"10.1016\/j.jpurol.2020.10.031","article-title":"Resolution of hydronephrosis after pyeloplasty in children","volume":"17","author":"V\u00e4rel\u00e4","year":"2021","journal-title":"J Pediatr Urol"},{"key":"B11","first-page":"164","article-title":"Dimensions of the normal ureter in infancy and childhood","volume":"5","author":"Cussen","year":"1967","journal-title":"Invest Urol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1177\/028418518502600412","article-title":"Normal ureteral diameter in infancy and childhood","volume":"26","author":"Hellstr\u00f6m","year":"1985","journal-title":"Acta Radiol Diagn (Stockh)"},{"key":"B13","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1089\/end.2017.0434","article-title":"Endoscopic management of primary obstructive megaureter: a systematic review","volume":"32","author":"Doudt","year":"2018","journal-title":"J Endourol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"405","DOI":"10.4111\/icu.2019.60.5.405","article-title":"Transvesicoscopic politano-leadbetter ureteral reimplantation in children with vesicoureteral reflux: a novel surgical technique","volume":"60","author":"Baek","year":"2019","journal-title":"Invest Clin Urol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1016\/j.transproceed.2020.10.029","article-title":"A new approach to the Hostile bladder in transplantation","volume":"53","author":"Nghiem","year":"2021","journal-title":"Transplant Proc"},{"key":"B16","doi-asserted-by":"publisher","first-page":"110.e1","DOI":"10.1016\/j.jpurol.2015.07.014","article-title":"Initial experiences of laparoscopic intravesical detrusorraphy using the politano-leadbetter technique","volume":"12","author":"Choi","year":"2016","journal-title":"J Pediatr Urol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1111\/bju.14785","article-title":"Postoperative bladder dysfunction and outcomes after minimally invasive extravesical ureteric reimplantation in children using a laparoscopic and a robot-assisted approach: results of a multicentre international survey","volume":"124","author":"Esposito","year":"2019","journal-title":"BJU Int"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1007\/s00345-015-1565-9","article-title":"Postoperative vesicoureteral reflux after high-pressure balloon dilation of the ureterovesical junction in primary obstructive megaureter. Incidence, management and predisposing factors","volume":"33","author":"Garc\u00eda-Aparicio","year":"2015","journal-title":"World J Urol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"224.e1","DOI":"10.1016\/j.jpurol.2021.12.004","article-title":"Pneumovesicoscopic ureteral reimplantation with intravesical tailoring of obstructive megaureter in pediatric patient","volume":"18","author":"Rudin","year":"2022","journal-title":"J Pediatr Urol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1089\/lap.2016.0456","article-title":"Laparoscopic-Assisted extravesical ureteral reimplantation and extracorporeal ureteral tapering repair for primary obstructive megaureter in children","volume":"27","author":"Lopez","year":"2017","journal-title":"J Laparoendosc Adv Surg Tech Part A"},{"key":"B21","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.urology.2019.09.003","article-title":"Robot-Assisted laparoscopic extravesical cross-trigonal ureteral reimplantation with tailoring for primary obstructive megaureter","volume":"134","author":"Neheman","year":"2019","journal-title":"Urology"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1016\/s0022-5347(17)42011-8","article-title":"Comparison of 2 different tapering techniques in megaureters","volume":"140","author":"Bakker","year":"1988","journal-title":"J Urol"},{"key":"B23","first-page":"99","article-title":"Is there a difference in the postoperative follow up of ureteropelvic junction obstruction according to age?","volume":"31","author":"Gonz\u00e1lez Ruiz","year":"2018","journal-title":"Cir Pediatr"},{"key":"B24","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.urology.2016.10.004","article-title":"Functional and morphological outcomes of pyeloplasty at different ages in prenatally diagnosed society of fetal urology grades 3-4 ureteropelvic junction obstruction: is it safe to wait?","volume":"101","author":"Jiang","year":"2017","journal-title":"Urology"}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2023.1164474\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T16:36:12Z","timestamp":1688747772000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2023.1164474\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,23]]},"references-count":24,"alternative-id":["10.3389\/fped.2023.1164474"],"URL":"https:\/\/doi.org\/10.3389\/fped.2023.1164474","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,23]]},"article-number":"1164474"}}