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Pediatr."],"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine short-term morbidity and mortality rates in the first state-wide Austrian neonatal cohort and comparison to (inter)national data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Observational, population-based cohort study, analyzing data of preterm infants (&amp;lt;32\u2009+\u20090 weeks of gestation) born between 2007 and 2020 (<jats:italic>n<\/jats:italic>\u2009=\u2009501) in an Austrian state who were admitted to the neonatal intensive care unit. Outcome criteria were mortality, neonatal morbidities: bronchopulmonary dysplasia (BPD), <jats:italic>severe<\/jats:italic> necrotizing enterocolitis (NEC), severe intraventricular hemorrhage (IVH grades III\u2013IV), severe retinopathy of prematurity (ROP grades III\u2013V) and survival-free of major complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall survival rate was 95%, survival free of major complications was 79%. Prevalence for BPD was 11.2%, surgical NEC 4.0%, severe IVH 4.6%, and for severe ROP 2.6%, respectively. In the extremely low gestational age neonates (ELGAN) born &amp;lt;28 weeks of gestation (<jats:italic>n<\/jats:italic>\u2009=\u2009158), survival was 88% and survival free of major complications 58.8%. Over time, mortality decreased significantly, predominantly driven by the improvement of infants born &amp;lt;28 week of gestation and survival free of major complications improved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrates a very low mortality rate that decreases over time. Short-term morbidities and survival free of major complications do not differ from (inter)national data in a similar group of very preterm infants. Standard operating procedures, simulation trainings and accordance to international trials may improve patient care and surpass center case loads.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2024.1336469","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T04:44:17Z","timestamp":1706849057000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Outcome in very preterm infants: a population-based study from a regional center in Austria"],"prefix":"10.3389","volume":"12","author":[{"given":"Karin","family":"Konzett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Riedl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anya","family":"Blassnig-Ezeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Gang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhard","family":"Simma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,2,2]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s00112-016-0149-0","article-title":"Management of premature infants at the border of viability: joint guidelines of the working group for neonatology and pediatric intensive care medicine of the Austrian society of pediatrics and adolescent medicine (\u00d6GKJ), the working group on ethics in pediatrics and adolescent medicine of the \u00d6GKJ and the institute for ethics and law in medicine at the university of Vienna (IERM)","volume":"165","author":"Berger","year":"2017","journal-title":"Monatsschr Kinderheilkd"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00112-021-01387-3","article-title":"f\u00fcr den Fachbeirat des \u00d6sterreichischen Fr\u00fchgeborenen-outcome-registers (\u00d6FGOR). 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