{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T08:16:05Z","timestamp":1790151365695,"version":"4.0.1"},"reference-count":46,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T00:00:00Z","timestamp":1715558400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intestinal malrotation is a rare condition, and its delayed diagnosis can lead to fatal consequences. This study aimed to investigate the identification and treatment of malrotation in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Clinical data, imaging, operative findings, and early postoperative outcomes of 75 children with malrotation were retrospectively analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age was 6.18\u2009\u00b1\u20094.93 days and 51.26\u2009\u00b1\u200970.13 months in the neonatal group (56 patients) and non-neonatal group (19 patients), respectively. Sixty-seven patients were under the age of 1 year at the time of diagnosis. The occurrence of bilious vomiting and jaundice was significantly higher in the neonatal group (89.29%) than that in the non-neonatal group (37.5%),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01, respectively. The incidence of abnormal ultrasound (US) findings was 97.30% and 100%, respectively, and the sensitivities of the upper gastrointestinal series were 84.21% and 87.5%, respectively. Sixty-six (88%) patients had midgut volvulus, including\n                      <jats:italic>in utero<\/jats:italic>\n                      volvulus (two patients) and irreversible intestinal ischemia (four patients). Most neonates (89.29%) underwent open Ladd's procedure with a shorter operative time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01). Reoperation was performed for postoperative complications (four patients) or missed comorbidities (two patients).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Non-bilious vomiting was the initial symptom in &amp;gt;10% of neonates and nearly 40% of non-neonates. This highlights the importance for emergency physicians and surgeons to be cautious about ruling out malrotation in patients with non-bilious vomiting. Utilizing US can obviate the need for contrast examinations owing to its higher diagnostic accuracy and rapid diagnosis and can be recommended as a first-line imaging technique. Additionally, open surgery is still an option for neonatal patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fped.2024.1390856","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T00:47:47Z","timestamp":1715561267000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Identification and treatment of intestinal malrotation with midgut volvulus in childhood: a multicenter retrospective study"],"prefix":"10.3389","volume":"12","author":[{"given":"Xiaofeng","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingquan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liandong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yewen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guojian","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingliang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiwu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,5,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.jpedsurg.2023.11.020","article-title":"Notable clinical differences between neonatal and post-neonatal intestinal malrotation: a multicenter review in Southern Japan","volume":"59","author":"Kedoin","year":"2024","journal-title":"J Pediatr Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s00383-023-05406-0","article-title":"Predictive factors of bowel resection for midgut volvulus based on an analysis of bi-center experiences in southern Japan","volume":"39","author":"Nagano","year":"2023","journal-title":"Pediatr Surg Int"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1016\/j.jpedsurg.2023.02.029","article-title":"Prenatal sonography in suspected proximal gastrointestinal obstructions: diagnostic accuracy and neonatal outcomes","volume":"58","author":"Engwall-Gill","year":"2023","journal-title":"J Pediatr Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/j.earlhumdev.2014.09.017","article-title":"Malrotation and intestinal atresias","volume":"90","author":"Adams","year":"2014","journal-title":"Early Hum Dev"},{"key":"B5","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.jss.2018.04.016","article-title":"Is less more? 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