{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T18:26:18Z","timestamp":1755800778754,"version":"3.44.0"},"reference-count":7,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Monosomy 45,X is commonly associated with congenital heart defects, particularly coarctation of the aorta (CoA). In this case, the patient developed respiratory distress due to hemodynamic instability from a large bidirectional patent ductus arteriosus (PDA) shunt and systemic hypoperfusion secondary to CoA, which complicated diagnosis and management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>We report a 34-week premature female neonate weighing 1.94\u2005kg, delivered via lower segment cesarean section (LSCS) due to oligohydramnios and intrauterine growth restriction. She exhibited characteristic features of Turner syndrome, including a webbed neck, low-set ears, widely spaced nipples, and lymphedema of the hands and feet. Karyotyping confirmed a 45,X monosomy. Echocardiography revealed a bicuspid aortic valve, juxtaductal coarctation of the aorta, a moderate-sized PDA with a bidirectional shunt, and suspected pulmonary hypertension. A contrast-enhanced CT aortogram confirmed the coarctation. The patient was managed with mechanical ventilation, continuous positive airway pressure (CPAP), surfactant therapy, and phototherapy. Rescue transcatheter balloon angioplasty was performed for the coarctation, followed by PDA ligation and surgical coarctation repair at a tertiary center, resulting in marked clinical improvement.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fped.2025.1607621","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T05:33:49Z","timestamp":1755149629000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of coarctation of aorta with Turner syndrome: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Musawer","family":"Khan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana","family":"Imtiaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Shoaib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malaika","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadia","family":"Zahra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Awais","family":"Sardar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asif Ullah","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamil Ahmad","family":"Kamil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.pedneo.2019.10.001","article-title":"Association between cardiovascular anomalies and karyotypes in Turner syndrome patients in Taiwan: a local cohort study","volume":"61","author":"Chou","year":"2020","journal-title":"Pediatr Neonatol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1186\/s13023-024-03337-0","article-title":"Turner syndrome where are we?","volume":"19","author":"Khan","year":"2024","journal-title":"Orphanet J Rare Dis"},{"key":"B3","doi-asserted-by":"publisher","first-page":"769","DOI":"10.3390\/diagnostics14070769","article-title":"Comprehensive oral diagnosis and management for women with Turner syndrome","volume":"14","author":"Tall\u00f3n-Walton","year":"2024","journal-title":"Diagnostics (Basel)"},{"key":"B4","doi-asserted-by":"publisher","first-page":"138","DOI":"10.3390\/jcdd8110138","article-title":"A review of recent developments in Turner syndrome research","volume":"8","author":"Huang","year":"2021","journal-title":"J Cardiovasc Dev Dis"},{"key":"B5","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.ando.2020.12.004","article-title":"Heart and Turner syndrome","volume":"82","author":"Donadille","year":"2021","journal-title":"Ann Endocrinol (Paris)"},{"key":"B6","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.avsg.2022.02.020","article-title":"Safety of aortic coarctation treatment in patients with Turner syndrome: a single-country case series and literature review","volume":"85","author":"Shahri","year":"2022","journal-title":"Ann Vasc Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.23880\/oajc-16000164","article-title":"An insight into interventions after previous coarctation of aorta repair","volume":"5","author":"Satsangi","year":"2021","journal-title":"Open Access J Cardiol"}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2025.1607621\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T12:31:39Z","timestamp":1755693099000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2025.1607621\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":7,"alternative-id":["10.3389\/fped.2025.1607621"],"URL":"https:\/\/doi.org\/10.3389\/fped.2025.1607621","relation":{},"ISSN":["2296-2360"],"issn-type":[{"type":"electronic","value":"2296-2360"}],"subject":[],"published":{"date-parts":[[2025,8,14]]},"article-number":"1607621"}}