{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:14:10Z","timestamp":1792512850409,"version":"4.5.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Acute suppurative thyroiditis (AST) is a rare, potentially life-threatening bacterial infection of the thyroid gland, characterized by rapid progression. We report a rare pediatric case of AST caused by <jats:italic>Eikenella corrodens<\/jats:italic>, secondary to a pyriform sinus fistula (PSF), initially misdiagnosed as subacute thyroiditis (SAT). A retrospective analysis highlights the diagnostic challenges and emphasizes the need for early suspicion of PSF in recurrent AST. Timely imaging (CT\/laryngoscopy) and pathogen-directed antibiotics are critical to prevent life-threatening complications. This case underscores the importance of considering atypical pathogens and underlying anatomical anomalies in pediatric AST to guide targeted therapy.<\/jats:p>","DOI":"10.3389\/fped.2025.1614566","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T04:10:35Z","timestamp":1754626235000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Pediatric acute suppurative thyroiditis caused by Eikenella corrodens: a rare presentation revealing pyriform sinus fistula"],"prefix":"10.3389","volume":"13","author":[{"given":"Fan","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanchao","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqiang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,8]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1089\/thy.2008.0146","article-title":"Acute bacterial suppurative thyroiditis: a clinical review and expert opinion","volume":"20","author":"Paes","year":"2010","journal-title":"Thyroid"},{"key":"B2","doi-asserted-by":"publisher","first-page":"bcr2015213231","DOI":"10.1136\/bcr-2015-213231","article-title":"Acute suppurative thyroiditis secondary to urinary tract infection by E. coli: a rare clinical scenario","volume":"2016","author":"Sen","year":"2016","journal-title":"BMJ Case Rep"},{"key":"B3","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1093\/clinids\/5.1.108","article-title":"Infectious diseases of the thyroid gland","volume":"5","author":"Berger","year":"1983","journal-title":"Rev Infect Dis"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1086\/514998","article-title":"Suppurative acinetobacter baumanii thyroiditis with bacteremic pneumonia: case report and review","volume":"27","author":"Yu","year":"1998","journal-title":"Clin Infect Dis"},{"key":"B5","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/cen.14440","article-title":"Suppurative thyroiditis: systematic review and clinical guidance","volume":"95","author":"Lafontaine","year":"2021","journal-title":"Clin Endocrinol (Oxf)"},{"key":"B6","doi-asserted-by":"publisher","first-page":"104","DOI":"10.6065\/apem.2014.19.2.104","article-title":"Refractory acute suppurative thyroiditis secondary to pyriform sinus fistula","volume":"19","author":"Seo","year":"2014","journal-title":"Ann Pediatr Endocrinol Metab"},{"key":"B7","doi-asserted-by":"publisher","first-page":"eRC5273","DOI":"10.31744\/einstein_journal\/2020RC5273","article-title":"Acute spontaneous suppurative thyroiditis caused by Eikenella corrodens presented with thyrotoxicosis","volume":"18","author":"Akhanl\u0131","year":"2020","journal-title":"Einstein (Sao Paulo)"},{"key":"B8","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1186\/s12902-019-0458-0","article-title":"Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes","volume":"19","author":"Falhammar","year":"2019","journal-title":"BMC Endocr Disord"},{"key":"B9","doi-asserted-by":"publisher","first-page":"E116","DOI":"10.1111\/j.1440-1754.2011.02075.x","article-title":"Acute suppurative thyroiditis in young children","volume":"48","author":"Wongphyat","year":"2012","journal-title":"J Paediatr Child Health"},{"key":"B10","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1017\/s0195941700063797","article-title":"Eikenella corrodens","volume":"7","author":"Decker","year":"1986","journal-title":"Infect Control"},{"key":"B11","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1128\/aac.14.4.639","article-title":"Susceptibility of Eikenella corrodens to ten cephalosporins","volume":"14","author":"Goldstein","year":"1978","journal-title":"Antimicrob Agents Chemother"},{"key":"B12","doi-asserted-by":"publisher","first-page":"42","DOI":"10.17925\/ee.2019.15.1.42","article-title":"Idiopathic thyroid abscess\u2014a rare occurrence","volume":"15","author":"Chainchel Singh","year":"2019","journal-title":"Eur Endocrinol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/s0140-6736(79)91208-x","article-title":"Internal fistula as a route of infection in acute suppurative thyroiditis","volume":"1","author":"Takai","year":"1979","journal-title":"Lancet"},{"key":"B14","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1177\/000313480707300719","article-title":"Thyroid abscess: case report and review of the literature","volume":"73","author":"Herndon","year":"2007","journal-title":"Am Surg"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1016\/j.jpedsurg.2008.12.001","article-title":"Management of congenital fourth branchial arch anomalies: a review and analysis of published cases","volume":"44","author":"Nicoucar","year":"2009","journal-title":"J Pediatr Surg"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1297831","DOI":"10.3389\/fped.2024.1297831","article-title":"A novel and efficient surgical procedure for pyriform sinus fistulas in children","volume":"12","author":"Chen","year":"2024","journal-title":"Front Pediatr"},{"key":"B17","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1080\/23772484.2016.1244470","article-title":"Successful transoral surgical closure of a hypopharyngeal pyriform sinus fistula: a case report","volume":"1","author":"Yamazaki","year":"2016","journal-title":"Acta Otolaryngol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"rjaa170","DOI":"10.1093\/jscr\/rjaa170","article-title":"Surgical approach and treatment for the orifice of a pyriform sinus fistula: a case report and literature review","volume":"2020","author":"Tatekawa","year":"2020","journal-title":"J Surg Case Rep"}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2025.1614566\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T04:10:36Z","timestamp":1754626236000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2025.1614566\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,8]]},"references-count":18,"alternative-id":["10.3389\/fped.2025.1614566"],"URL":"https:\/\/doi.org\/10.3389\/fped.2025.1614566","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,8]]},"article-number":"1614566"}}