{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T19:17:51Z","timestamp":1782415071133,"version":"3.54.5"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec>\n                    <jats:title>Background\/purpose<\/jats:title>\n                    <jats:p>Unplanned reoperation rates becoming a critical metric for evaluating healthcare quality and have received increasing attention in recent years. Intestinal atresia (IA) has a high rate of unplanned reoperations. The purpose of this study is to evaluate the thirty-day unplanned reoperation rates and their risk factors in neonates with intestinal atresias after primary anastomosis surgery, and to construct a predictive nomogram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We developed and internally validated a predictive model from a retrospective cohort of 200 neonates admitted to our hospital for primary anastomosis surgery. The primary outcome was thirty-day unplanned reoperation rates. Independent factors significantly associated with thirty-day unplanned reoperation rates were identified using multivariable logistic regression analysis. The effectiveness of the developed nomogram was evaluated through calibration, discrimination, and clinical utility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The incidence of thirty-day unplanned reoperation rates was 11%. Multivariable analysis identified the type of bowel anastomosis and combined meconium peritonitis as independent factors predicting thirty-day unplanned reoperation rates. The derivation model showed good discrimination, with a C-index of 0.791 (95% CI, 0.685\u20130.897), and good calibration (Hosmer\u2013Lemeshow test\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.231). The analysis of the decision curve showed that the nomogram was beneficial in clinical practice.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We developed a nomogram to predict thirty-day unplanned reoperations of primary anastomosis in neonates with IA. This prediction model may enable assist in clinical decision-making, patient counseling, and treatment planning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fped.2025.1660827","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:51:05Z","timestamp":1761720665000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Establishment and validation of a nomogram to predict thirty-day unplanned reoperations of primary anastomosis in neonates with intestinal atresias"],"prefix":"10.3389","volume":"13","author":[{"given":"Zhixiong","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihao","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingkun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1542\/pir.2021-005177","article-title":"Intestinal 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